Wednesday, July 2, 2025 7/2/2025

Determinants of Palliative Care Effectiveness for Patients with Metastatic Cancer

Award Number: R37CA246565
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 02/03/2021
PERIOD OF PERFORMANCE END DATE: 01/31/2026

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Determinants of Palliative Care Effectiveness for Patients with Metastatic Cancer - Project Summary Palliative care is an interdisciplinary model of care with the overarching goal of improving quality of life for patients with serious illness through symptom management, provision of psychosocial support, elicitation of preferences and aiding decision-making. Prior studies have demonstrated that specialist palliative care is associated with decreases in treatment intensity and improvements in quality of life, but have also suggested that existing heterogeneity among palliative care teams may be associated with variability in their effectiveness. Early integration of specialist palliative care for patients with advanced cancer has been recommended by the American Society of Clinical Oncology. However, as hospitals race to implement palliative care programs to meet these guidelines, there is little evidence to guide them as to which ingredients are necessary for effective care delivery. The proposed research will target this important knowledge gap by 1) quantifying the association between use of specialist palliative care and end-of-life quality metrics in cancer care, 2) examining whether differences in specialist palliative care implementation (as measured by key variables reflecting team attributes and operational characteristics) are associated with improvements in quality metrics and 3) using qualitative research methods to understand how programs operationalize care delivery within different hospital settings. This project will create and utilize a novel data source that combines nationwide patient and hospital-level data, detailed data on palliative care programs and valid information on receipt of specialist palliative care. Quantitative analyses of this unique dataset will be followed by in-depth site visits to six select palliative care programs; together, these data will be used to develop an actionable roadmap that may be used to refine existing palliative care programs and inform implementation of future programs to ensure effective delivery of palliative care for patients with cancer. This project represents an important advance in understanding the role of palliative care specialists in cancer care, as prior work has focused on whether specialist palliative care is associated with improved outcomes, while this work will focus identifying the conditions under which specialist palliative care may achieve improved outcomes.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $513,476 )
2025	2025	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cancer Cause and Prevention Research	000	5	2/13/2025	NON-COMPETING CONTINUATION	$513,476
														Subtotal = $513,476

Issue Date FY: 2024 ( Subtotal = $448,284 )
2024	2024	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cancer Cause and Prevention Research	001	4	4/16/2024	NON-COMPETING CONTINUATION	$29,228
2024	2024	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cancer Cause and Prevention Research	000	4	2/27/2024	NON-COMPETING CONTINUATION	$419,056
														Subtotal = $448,284

Issue Date FY: 2023 ( Subtotal = $602,298 )
2023	2023	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cancer Cause and Prevention Research	000	3	1/31/2023	NON-COMPETING CONTINUATION	$602,298
														Subtotal = $602,298

Issue Date FY: 2022 ( Subtotal = $465,149 )
2022	2022	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cancer Cause and Prevention Research	000	2	2/18/2022	NON-COMPETING CONTINUATION	$418,629
2022	2022	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cancer Cause and Prevention Research	001	2	5/5/2022	NON-COMPETING CONTINUATION	$46,520
														Subtotal = $465,149

Issue Date FY: 2021 ( Subtotal = $666,091 )
2021	2021	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cancer Cause and Prevention Research	000	1	2/3/2021	NEW	$689,994
2021	2021	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cancer Cause and Prevention Research	001	1	3/5/2021	NEW	-$23,903
														Subtotal = $666,091

Grand Total All Awards = $2,695,298

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Determinants of Palliative Care Effectiveness for Patients with Metastatic Cancer

Award Number: R37CA246565

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 02/03/2021

PERIOD OF PERFORMANCE END DATE: 01/31/2026

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