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Organizational strategies for improving evidence-uptake in intensive care

Award Number: R35HL144804
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 01/21/2019
PERIOD OF PERFORMANCE END DATE: 02/28/2026

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Organizational strategies for improving evidence-uptake in intensive care - ABSTRACT In recent decades multiple high-profile clinical trials have provided a rigorous evidence base for the care of patients with acute respiratory failure requiring mechanical ventilation. Yet many patients still do not receive these evidence-based treatments proven to save lives. The overarching goal of our research program is to address this issue by defining the relationship between ICU organizational behavior and evidence-uptake in critical care. Drawing off the rapidly evolving fields of organizational psychology, decision science, and biomedical informatics, we will broadly investigate the ways in which the interactive behaviors of the ICU team members can both facilitate and hinder efficient translation of evidence into practice. We will pursue three integrated and complimentary lines of research: (1) developing and refining novel strategies for measuring critical care performance; (2) investigating the role of collective intelligence and transactive memory as key sociological mediators of evidence-uptake in critical care; and (3) improving the value of novel decisional support tools such as checklists and electronic prompting for the use of evidence-based practice. To perform this research we will leverage existing collaborations with state and regional health systems as well as the expertise of the principal investigator, a physician-scientist with over 15 years’ experience studying the link between ICU organization and outcome for patients with critical illness. Together, our results will provide hospitals and clinicians with innovative tools for improving critical care performance on a national scale, directly leading improved outcomes for patients with acute respiratory failure and other forms of critical illness.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2025	UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	4200 FIFTH AVENUE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Lung Diseases Research	000	7	11/20/2025	NON-COMPETING CONTINUATION	$0
2026	2025	UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	4200 FIFTH AVENUE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Lung Diseases Research	001	7	12/12/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $917,190 )
2025	2025	UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	4200 FIFTH AVENUE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Lung Diseases Research	000	7	12/13/2024	NON-COMPETING CONTINUATION	$825,470
2025	2025	UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	4200 FIFTH AVENUE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Lung Diseases Research	001	7	8/12/2025	NON-COMPETING CONTINUATION	$91,720
														Subtotal = $917,190

Issue Date FY: 2024 ( Subtotal = $1,061,665 )
2024	2024	UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	4200 FIFTH AVENUE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Lung Diseases Research	001	6	6/24/2024	NON-COMPETING CONTINUATION	$73,702
2024	2024	UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	4200 FIFTH AVENUE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Lung Diseases Research	002	6	9/18/2024	SUPPLEMENT FOR EXPANSION	$158,820
2024	2024	UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	4200 FIFTH AVENUE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Lung Diseases Research	000	6	11/14/2023	NON-COMPETING CONTINUATION	$829,143
														Subtotal = $1,061,665

Issue Date FY: 2023 ( Subtotal = $923,836 )
2023	2023	UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION	4200 FIFTH AVENUE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Lung Diseases Research	001	5	3/3/2023	NON-COMPETING CONTINUATION	$92,384
2023	2023	UNIVERSITY OF PITTSBURGH, THE	4200 5TH AVE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Lung Diseases Research	000	5	11/19/2022	NON-COMPETING CONTINUATION	$831,452
														Subtotal = $923,836

Issue Date FY: 2022 ( Subtotal = $924,218 )
2022	2022	UNIVERSITY OF PITTSBURGH, THE	4200 5TH AVE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Lung Diseases Research	002	4	6/13/2022	NON-COMPETING CONTINUATION	$92,422
2022	2022	UNIVERSITY OF PITTSBURGH, THE	4200 5TH AVE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Lung Diseases Research	001	4	12/14/2021	NON-COMPETING CONTINUATION	$831,796
2022	2021	UNIVERSITY OF PITTSBURGH, THE	4200 5TH AVE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Lung Diseases Research	000	3	12/1/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $924,218

Issue Date FY: 2021 ( Subtotal = $923,821 )
2021	2021	UNIVERSITY OF PITTSBURGH, THE	4200 5TH AVE	PITTSBURGH	PA	15260	ALLEGHENY	USA	Lung Diseases Research	001	3	5/24/2021	NON-COMPETING CONTINUATION	$92,384
2021	2021	UNIVERSITY OF PITTSBURGH THE	3520 FIFTH AVE	PITTSBURGH	PA	15213	ALLEGHENY	USA	Lung Diseases Research	000	3	11/23/2020	NON-COMPETING CONTINUATION	$831,437
														Subtotal = $923,821

Issue Date FY: 2020 ( Subtotal = $923,933 )
2020	2020	UNIVERSITY OF PITTSBURGH THE	3520 FIFTH AVE	PITTSBURGH	PA	15213	ALLEGHENY	USA	Lung Diseases Research	001	2	3/13/2020	NON-COMPETING CONTINUATION	$46,196
2020	2020	UNIVERSITY OF PITTSBURGH THE	3520 FIFTH AVE	PITTSBURGH	PA	15213	ALLEGHENY	USA	Lung Diseases Research	000	2	12/5/2019	NON-COMPETING CONTINUATION	$877,737
														Subtotal = $923,933

Issue Date FY: 2019 ( Subtotal = $922,387 )
2019	2019	UNIVERSITY OF PITTSBURGH THE	3520 FIFTH AVE	PITTSBURGH	PA	15213	ALLEGHENY	USA	Lung Diseases Research	000	1	1/20/2019	NEW	$922,387
														Subtotal = $922,387

Grand Total All Awards = $6,597,050

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Organizational strategies for improving evidence-uptake in intensive care

Award Number: R35HL144804

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 01/21/2019

PERIOD OF PERFORMANCE END DATE: 02/28/2026

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