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Internet Intervention to Prevent Major Depressive Episodes

Award Number: R34MH091231
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/20/2010
PERIOD OF PERFORMANCE END DATE: 01/31/2015

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Internet Intervention to Prevent Major Depressive Episodes - DESCRIPTION (provided by applicant): The University of California, San Francisco (UCSF) Latino Mental Health Research Program, based at San Francisco General Hospital (SFGH), proposes to develop evidence-based Internet interventions in Spanish and English to prevent major depressive episodes (MDEs). The current pilot project has three aims designed to set the stage for a subsequent randomized control trial of such an Internet intervention: Aim 1. Adaptation of a widely tested cognitive-behavioral intervention for Internet administration, and creation of a self-help research Website that will automatically recruit participants online, deliver the intervention online, and conduct follow-up assessments online. Aim 2. Usability testing of the Website with Spanish- and English-speaking men and women from public sector health clinics to assess and optimize, prior to launching the online pilot study: accessibility to as wide a range of individuals as possible, to reduce disparities; understanding of informed consent for the study; and understanding of the various study measures (i.e., measures of depression, self-efficacy, and so on). Aim 3. Conducting a nationwide online pilot study of the site in Spanish and English to examine: recruitment rates, response rates to specific ads to identify best recruitment strategies, and characteristics of responders; information on the effectiveness of informed consent procedures to enhance understanding of key aspects of the study; utilization patterns of each element of the site; and efficacy of methods to reduce follow-up attrition. This application is responsive to NIMH Strategic Objective 3 (to develop new and better interventions that incorporate the diverse needs and circumstances of people with mental illnesses) and Objective 4 (to strengthen the public health impact of NIMH-supported research). The Internet intervention would provide a highly innovative means of delivering preventive mental health services for undertreated and underserved populations. An online intervention of this type has the potential to reach millions of individuals nationally and internationally, thereby maximizing the public health benefit of NIMH funding. PUBLIC HEALTH RELEVANCE: Major depression affects millions of people and is the number one cause of disability worldwide. An Internet intervention that prevents depression and that can reach at-risk individuals in their own language, 24 hours a day, anywhere with Web access, would greatly increase mental health outreach in the U.S. and beyond. The scalability of such an intervention could also make it very cost effective as a public health measure.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2014 ( Subtotal = $0 )
2014	2012	PALO ALTO UNIVERSITY INC	1791 ARASTRADERO ROAD	PALO ALTO	CA	94304	SANTA CLARA	USA	Mental Health Research Grants	000	4	4/14/2014	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
														Subtotal = $0

Issue Date FY: 2013 ( Subtotal = -$59,465 )
2013	2012	PALO ALTO UNIVERSITY INC	940 EAST MEADOW DRIVE	PALO ALTO	CA	94303	SANTA CLARA	USA	Mental Health Research Grants	001	4	3/11/2013	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$130,300
2013	2012	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Mental Health Research Grants	000	3	3/7/2013	NON-COMPETING CONTINUATION	-$189,765
														Subtotal = -$59,465

Issue Date FY: 2012 ( Subtotal = $189,765 )
2012	2012	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Mental Health Research Grants	000	3	4/5/2012	NON-COMPETING CONTINUATION	$189,765
														Subtotal = $189,765

Issue Date FY: 2011 ( Subtotal = $327,424 )
2011	2011	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Mental Health Research Grants	000	2	4/15/2011	NON-COMPETING CONTINUATION	$219,004
2011	2011	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Mental Health Research Grants	001	2	6/17/2011	SUPPLEMENT FOR EXPANSION	$86,520
2011	2011	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Mental Health Research Grants	002	2	7/19/2011	NON-COMPETING CONTINUATION	$21,900
														Subtotal = $327,424

Issue Date FY: 2010 ( Subtotal = $278,100 )
2010	2010	UNIVERSITY OF CALIFORNIA-SAN FRANCISCO	BOX 0812	SAN FRANCISCO	CA	94143	SAN FRANCISCO	USA	Mental Health Research Grants	000	1	7/20/2010	NEW	$278,100
														Subtotal = $278,100

Grand Total All Awards = $735,824

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Internet Intervention to Prevent Major Depressive Episodes

Award Number: R34MH091231

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/20/2010

PERIOD OF PERFORMANCE END DATE: 01/31/2015

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