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Virtual Mindful After Cancer Intervention to Promote Sexual Health for Breast and Gynecologic Cancer Survivors

Award Number: R34CA286710
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/17/2024
PERIOD OF PERFORMANCE END DATE: 08/31/2027

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Virtual Mindful After Cancer Intervention to Promote Sexual Health for Breast and Gynecologic Cancer Survivors - PROJECT SUMMARY Sexual concerns are among the most common, distressing, and persistent aspects of life after cancer. For at least half of breast and gynecological cancer survivors, cancer treatment adversely affects physical, social, or psychological aspects of sexual health. Examples include vaginal pain, loss of sensation, poor body image, disrupted intimate relationships, and loss of sexual interest. Despite this, sexual concerns are often unaddressed, with one major reason being lack of access to evidence-based interventions. In short, to improve sexual health in cancer survivorship, there is an urgent need to test and implement accessible, evidence-based interventions that can effectively reach cancer survivors in need. Mindfulness-based interventions have demonstrated efficacy in addressing a range of sexual concerns and improving psychosexual health outcomes. Our preliminary research demonstrated support for the acceptability of a virtually delivered mindfulness-based intervention adapted specifically for breast and gynecological cancer survivors experiencing sexual concerns. However, a more rigorous evaluation of this promising intervention, called Mindful After Cancer (MAC), is needed to support wide implementation and dissemination. A pragmatic trial would be ideal because it would facilitate the evaluation of MAC in the context of routine practice, which leads to more generalizable results and shortens the gap from research to implementation outside of the trial setting, thus more quickly increasing access for cancer survivors in need. The Specific Aims of the proposed R34 are 1) To conduct a pilot trial in preparation for a future multisite pragmatic trial of the virtual MAC intervention and 2) To identify contextual factors that may shape equitable reach and future implementation of the intervention. Our feasibility objectives are to develop protocols for 1) recruitment, 2) retention, and 3) training and supervision for adequate intervention fidelity for the planned future trial. Results of the proposed pilot trial will provide a robust scientific foundation and preparation for a rigorously designed multisite pragmatic trial. Evaluation of intervention access barriers and strategies to improve equitable recruitment and reach in both academic- and community-based care settings will inform future implementation and dissemination of mindfulness-based interventions such as MAC. Overall, results of the proposed project will readily translate to the protocol for rigorous, well-designed multisite pragmatic trial to evaluate the effectiveness of the virtual MAC intervention in real world conditions where we expect to implement and disseminate the intervention.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $297,170 )
2025	2025	OREGON STATE UNIVERSITY	1500 SW JEFFERSON AVE	CORVALLIS	OR	97331	BENTON	USA	Cancer Cause and Prevention Research	000	2	8/19/2025	NON-COMPETING CONTINUATION	$297,170
														Subtotal = $297,170

Issue Date FY: 2024 ( Subtotal = $318,589 )
2024	2024	OREGON STATE UNIVERSITY	1500 SW JEFFERSON AVE	CORVALLIS	OR	97331	BENTON	USA	Cancer Cause and Prevention Research	000	1	9/17/2024	NEW	$318,589
														Subtotal = $318,589

Grand Total All Awards = $615,759

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Virtual Mindful After Cancer Intervention to Promote Sexual Health for Breast and Gynecologic Cancer Survivors

Award Number: R34CA286710

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/17/2024

PERIOD OF PERFORMANCE END DATE: 08/31/2027

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