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CSHL Imaging Structure & Function in the Nervous System

Award Number: R25MH122360
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/15/2020
PERIOD OF PERFORMANCE END DATE: 02/28/2026

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CSHL Imaging Structure & Function in the Nervous System - Abstract Advances in light microscopy, digital image processing, and the development of a variety of powerful fluorescent probes present expanding opportunities for investigating the nervous system, from synaptic spines to networks in the brain. Addressing the need for intensive research training in this field, Cold Spring Harbor Laboratory will offer the annual three-week course on Imaging Structure and Function in the Nervous System, as part of its postgraduate summer training program in neurobiology (2020-2024). This intensive laboratory and lecture course will provide participants with the theoretical and practical knowledge to utilize emerging imaging technologies. The primary focus of the course will be on in vivo applications of light microscopy, particularly functional imaging with genetically encoded calcium indicators. Methods taught will include multi-photon and light-sheet microscopy, and combination of imaging with optogenetics. Lectures by leading experts will progress through basic concepts to presentation of cutting-edge methods. Students will learn the fundamentals of optics and microscopy, as well as the use of different types of cameras, laser scanning systems, in vivo preparations and image processing and analysis software. A strong emphasis is placed on building exercises that allow students to develop an understanding of basic principles, while also introducing them to a variety of state-of-the-art commercial systems. Robust experimental design and data collection/management strategies are integral features emphasized throughout the course. The lead instructors are chosen on the basis of their contributions to and knowledge of the field. In turn, they invite lecturers who have made significant contributions in their fields to give up-to-the-minute reports on the underlying technology and their current research. The trainees are chosen by the course faculty from larger pools of applicants and range from graduate students to senior investigators and research physicians. This intensive research training program enrolls a diverse cadre of researchers who can immediately transfer techniques and concepts learned during the course to their own research projects and interests, while embedding the trainees in a collaborative network of researchers interested in using advanced light microscopy techniques to the study of brain function and dysfunction. The faculty are encouraged to present relevant methodological approaches in the broader context of brain function and mental health research. Methods and concepts taught in the course are disseminated to the wider research community through the publication of laboratory manuals and online resources.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2024	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPG HBR	NY	11724	SUFFOLK	USA	Mental Health Research Grants	000	5	5/12/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $158,630 )
2024	2024	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Mental Health Research Grants	000	5	2/29/2024	NON-COMPETING CONTINUATION	$158,630
														Subtotal = $158,630

Issue Date FY: 2023 ( Subtotal = $158,630 )
2023	2023	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Mental Health Research Grants	000	4	1/31/2023	NON-COMPETING CONTINUATION	$158,630
														Subtotal = $158,630

Issue Date FY: 2022 ( Subtotal = $158,630 )
2022	2022	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Mental Health Research Grants	000	3	2/19/2022	NON-COMPETING CONTINUATION	$142,767
2022	2022	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Mental Health Research Grants	001	3	6/3/2022	NON-COMPETING CONTINUATION	$15,863
														Subtotal = $158,630

Issue Date FY: 2021 ( Subtotal = $158,630 )
2021	2021	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Mental Health Research Grants	000	2	2/17/2021	NON-COMPETING CONTINUATION	$158,630
														Subtotal = $158,630

Issue Date FY: 2020 ( Subtotal = $158,630 )
2020	2020	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Mental Health Research Grants	000	1	4/9/2020	NEW	$158,630
														Subtotal = $158,630

Grand Total All Awards = $793,150

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CSHL Imaging Structure & Function in the Nervous System

Award Number: R25MH122360

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/15/2020

PERIOD OF PERFORMANCE END DATE: 02/28/2026

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