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Training in Methods of Computational Neuroscience (MCN)

Award Number: R25MH062204
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/22/2000
PERIOD OF PERFORMANCE END DATE: 06/30/2025

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Training in Methods of Computational Neuroscience (MCN) - ABSTRACT The Methods in Computational Neuroscience (MCN) course at the Marine Biological Laboratory in Woods Hole, MA provides a unique training opportunity to equip students with cutting edge skills and conceptual foundations of computational methods to understanding the biological function and neural mechanisms of brain cells, circuits, and behavior. MCN is an intense lecture and computer laboratory course targeted to a talented mix of students with complementary expertise in biological and mathematical sciences. MCN students interact one-on-one with internationally renowned scientists and carry out hands-on, project-based training with a wide variety of computational techniques and approaches. The goals of the MCN course are to train students 1) in the concepts and methods of computational approaches to understanding brain function 2) in the mathematical foundations and techniques for the analysis of neural data 3) to use computational tools to solve fundamental questions in neurobiology, 4) to use computational methods to diagnose and treat human brain disorders and 5) to foster interdisciplinary collaborations that lead to long term interactions and mentorship. The course provides in-depth instruction on how to use computational approaches to solve fundamental problems in neurobiology using experimental techniques applied across a wide range of biological scales from molecules to behavior. This is accomplished through hands-on training in the mathematical foundations and techniques for the model-based, statistical and theoretical analysis of neural data in the context of mechanistic descriptions of neurons, networks, and brain systems. The MCN course continually updates its computational topics that are relevant to new experimental advances, such anatomical connectivity at microstructural and brain-wide scales, high density measurements using electrical and optical recording, and causal perturbations of neural circuits using optogenetics. These new topics include state-space trajectory analysis, deep networks, compressed sensing, advanced statistical inference, manifold learning, dimensionality reduction, analysis of large data sets including brain wide imaging and large scale cell-type specific connectivity. An additional innovation is an increased emphasis on computational approaches to understanding and addressing brain disorders, including the emerging field of computational psychiatry. Central to the course is an environment of intense interactions with a group of dedicated faculty, many of whom devote weeks or even the entire month to work with students. In the last half of the course students devote concentrated effort to novel cutting edge research projects mentored by a team of faculty and teaching assistants. The course fosters a collegial, international environment that advances student careers by providing students with networking opportunities that lead to long-term interactions, mentorship, and collaborations.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $213,596 )
2024	2024	THE MARINE BIOLOGICAL LABORATORY	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	25	6/18/2024	NON-COMPETING CONTINUATION	$213,596
														Subtotal = $213,596

Issue Date FY: 2023 ( Subtotal = $213,596 )
2023	2023	THE MARINE BIOLOGICAL LABORATORY	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	24	6/28/2023	NON-COMPETING CONTINUATION	$213,596
														Subtotal = $213,596

Issue Date FY: 2022 ( Subtotal = $213,596 )
2022	2022	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	23	7/1/2022	NON-COMPETING CONTINUATION	$213,596
														Subtotal = $213,596

Issue Date FY: 2021 ( Subtotal = $213,596 )
2021	2021	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	002	22	7/15/2021	NON-COMPETING CONTINUATION	$213,596
2021	2020	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	001	21	7/1/2021	COMPETING CONTINUATION	$1,367
2021	2019	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	20	7/1/2021	NON-COMPETING CONTINUATION	-$1,367
														Subtotal = $213,596

Issue Date FY: 2020 ( Subtotal = $213,596 )
2020	2020	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	001	21	4/16/2020	COMPETING CONTINUATION	$213,596
2020	2019	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	20	11/9/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $213,596

Issue Date FY: 2019 ( Subtotal = $186,287 )
2019	2019	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	20	6/5/2019	NON-COMPETING CONTINUATION	$186,287
														Subtotal = $186,287

Issue Date FY: 2018 ( Subtotal = $186,287 )
2018	2018	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	001	19	9/15/2018	NON-COMPETING CONTINUATION	$0
2018	2018	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	19	6/27/2018	NON-COMPETING CONTINUATION	$186,287
														Subtotal = $186,287

Issue Date FY: 2017 ( Subtotal = $186,287 )
2017	2017	MARINE BIOLOGICAL LABORATORY, THE	7 M B L ST	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	18	6/22/2017	NON-COMPETING CONTINUATION	$186,287
														Subtotal = $186,287

Issue Date FY: 2016 ( Subtotal = $186,287 )
2016	2016	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	17	9/7/2016	NON-COMPETING CONTINUATION	$186,287
														Subtotal = $186,287

Issue Date FY: 2015 ( Subtotal = $186,287 )
2015	2015	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	16	9/22/2015	COMPETING CONTINUATION	$186,287
														Subtotal = $186,287

Issue Date FY: 2014 ( Subtotal = $161,290 )
2014	2014	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	15	7/8/2014	NON-COMPETING CONTINUATION	$161,290
														Subtotal = $161,290

Issue Date FY: 2013 ( Subtotal = $154,838 )
2013	2013	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	14	7/25/2013	NON-COMPETING CONTINUATION	$154,838
														Subtotal = $154,838

Issue Date FY: 2012 ( Subtotal = $161,290 )
2012	2012	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	13	7/17/2012	NON-COMPETING CONTINUATION	$161,290
														Subtotal = $161,290

Issue Date FY: 2011 ( Subtotal = $161,290 )
2011	2011	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	12	7/26/2011	NON-COMPETING CONTINUATION	$161,290
														Subtotal = $161,290

Issue Date FY: 2010 ( Subtotal = $162,918 )
2010	2010	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	001	11	9/20/2010	COMPETING CONTINUATION	$162,918
2010	2010	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	002	11	9/29/2010	COMPETING CONTINUATION	$0
2010	2009	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	10	9/15/2010	NON-COMPETING CONTINUATION	$0
														Subtotal = $162,918

Issue Date FY: 2009 ( Subtotal = $176,486 )
2009	2009	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	10	7/31/2009	NON-COMPETING CONTINUATION	$176,486
														Subtotal = $176,486

Issue Date FY: 2008 ( Subtotal = $169,736 )
2008	2008	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	9	7/11/2008	NON-COMPETING CONTINUATION	$169,736
														Subtotal = $169,736

Issue Date FY: 2007 ( Subtotal = $169,677 )
2007	2007	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	8	7/13/2007	NON-COMPETING CONTINUATION	$169,677
														Subtotal = $169,677

Issue Date FY: 2006 ( Subtotal = $163,185 )
2006	2006	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	7	7/25/2006	NON-COMPETING CONTINUATION	$163,185
														Subtotal = $163,185

Issue Date FY: 2005 ( Subtotal = $158,442 )
2005	2005	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	Mental Health Research Grants	000	6	8/15/2005	COMPETING CONTINUATION	$158,442
														Subtotal = $158,442

Issue Date FY: 2004 ( Subtotal = $133,797 )
2004	2004	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	UNKNOWN	000	5	7/13/2004	NON-COMPETING CONTINUATION	$133,797
														Subtotal = $133,797

Issue Date FY: 2003 ( Subtotal = $129,900 )
2003	2003	MARINE BIOLOGICAL LABORATORY	7 MBL STREET	WOODS HOLE	MA	02543	BARNSTABLE	USA	UNKNOWN	000	4	8/15/2003	NON-COMPETING CONTINUATION	$129,900
														Subtotal = $129,900

Grand Total All Awards = $4,269,697

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Training in Methods of Computational Neuroscience (MCN)

Award Number: R25MH062204

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/22/2000

PERIOD OF PERFORMANCE END DATE: 06/30/2025

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