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Transforming Analytical Learning in the Era of Big Data: A Summer Institute in Biostatistics and Data Science

Award Number: R25HL161795
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/01/2022
PERIOD OF PERFORMANCE END DATE: 05/31/2027

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Transforming Analytical Learning in the Era of Big Data: A Summer Institute in Biostatistics and Data Science - The emergence of artificial intelligence and multi-modal data streams are taking us far beyond a structured, rectangular data matrix (as described in classical statistics courses), underscoring the importance of harnessing information from heterogeneous data sources and turning them into actionable knowledge. Building an intellectually dynamic and computationally mature workforce in data science is more important than ever. We propose a six-week long undergraduate summer institute in Biostatistics and Data Science: “Transforming Analytical Learning in the Era of Big Data” to be held in person at the Department of Biostatistics, Yale School of Public Health with a group of approximately 25 undergraduate students from 2025-2026. The program builds on the success of past iterations of the summer program known as Big Data Summer Institute (BDSI) at the University of Michigan supported by a NIH BD2K Courses and Skills grant award (2016-2018) and a SIBS award from NHLBI (2019-2024). Over the past nine years we have trained 357 undergraduate students. Of the students who have finished their undergraduate degree, approximately 60% have pursued graduate education in a relevant discipline and 47 have already enrolled in a relevant graduate program at the University of Michigan. We propose to transfer the last two years of the ongoing award to Yale University as the PI and founding director of the program, Bhramar Mukherjee has recently moved to Yale University. The structure of the program remains almost identical though the location and personnel will change. We plan to expose program students to techniques, skills and problems at the intersection of Big Data and Human Health. We primarily focus on four genres of health Big Data arising in Electronic Health Records, Genomics, Infectious Disease Epidemiology and Imaging. The mentored research projects will be defined primarily in cardiovascular and infectious diseases in collaboration with clinicians and public health scientists. The trainees will be taught and mentored by a team of interdisciplinary faculty from Biostatistics, Statistics, Biomedical Data Science, Computer Science and Engineering, Epidemiology, Social Sciences, and Medicine, reflecting the shared intellectual landscape needed for Big Data research. At the conclusion of the program there will be a capstone symposium showcasing the research of the students via poster and oral presentation. There will be lectures by Yale researchers, outside guests and a professional development workshop to prepare the students for graduate school. Along the way, students are expected to form lasting bonds over shared research experiences and social activities. The program has strong institutional support from multiple units and centers on Yale New Haven campus and leverages the cross-disciplinary intellectual richness of Yale University and Yale College. The students will reside in Benjamin Franklin College, one of the newest Yale residential colleges. The resources developed for the summer institute, including lectures, assignments, projects, template codes and datasets will be freely available through a public facing course webpage and a YouTube channel so that this format can be replicated anywhere in the world. This democratic dissemination plan will lead to access of teaching and training material in this new field of health data science across the world. The overarching goal of our summer institute in big data is to recruit and train the next generation of data scientists using a non-traditional, active learning paradigm and engage them in influential research related to human health. We aspire to teach, mentor, grow undergraduate trainees in ways that will shape their vision for a career in data science. Our goal is to create an inspiring educational experience that will have a transformative impact on the future career trajectories of our trainees. Our long-term objective is to create a skilled and motivated research workforce to


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2024	REGENTS OF THE UNIVERSITY OF MICHIGAN	1109 GEDDES AVE STE 3300	ANN ARBOR	MI	48109	WASHTENAW	USA	Cardiovascular Diseases Research	000	3	1/18/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $244,735 )
2025	2025	YALE UNIV	150 MUNSON ST	NEW HAVEN	CT	06511	SOUTH CENTRAL CT	USA	Cardiovascular Diseases Research	001	4	9/15/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$244,735
2025	2024	REGENTS OF THE UNIVERSITY OF MICHIGAN	1109 GEDDES AVE STE 3300	ANN ARBOR	MI	48109	WASHTENAW	USA	Cardiovascular Diseases Research	000	3	9/15/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $244,735

Issue Date FY: 2024 ( Subtotal = $242,033 )
2024	2024	REGENTS OF THE UNIVERSITY OF MICHIGAN	1109 GEDDES AVE, SUITE 3300	ANN ARBOR	MI	48109	WASHTENAW	USA	Cardiovascular Diseases Research	000	3	6/13/2024	NON-COMPETING CONTINUATION	$242,033
														Subtotal = $242,033

Issue Date FY: 2023 ( Subtotal = $242,033 )
2023	2023	REGENTS OF THE UNIVERSITY OF MICHIGAN	1109 GEDDES AVE, SUITE 3300	ANN ARBOR	MI	48109	WASHTENAW	USA	Cardiovascular Diseases Research	000	2	6/16/2023	NON-COMPETING CONTINUATION	$242,033
														Subtotal = $242,033

Issue Date FY: 2022 ( Subtotal = $242,033 )
2022	2022	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Cardiovascular Diseases Research	001	1	3/3/2022	NEW	$0
2022	2022	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Cardiovascular Diseases Research	000	1	1/11/2022	NEW	$242,033
														Subtotal = $242,033

Grand Total All Awards = $970,834

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Transforming Analytical Learning in the Era of Big Data: A Summer Institute in Biostatistics and Data Science

Award Number: R25HL161795

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/01/2022

PERIOD OF PERFORMANCE END DATE: 05/31/2027

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