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CSHL Course on Advanced Sequencing Technologies & Bioinformatics Analysis

Award Number: R25HG006424
ORGANIZATION: NATIONAL HUMAN GENOME RESEARCH INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/10/2012
PERIOD OF PERFORMANCE END DATE: 06/30/2026

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View Award Description

CSHL Course on Advanced Sequencing Technologies & Bioinformatics Analysis - This Cold Spring Harbor annual short course will train a broad cohort of biological and biomedical scientists in the latest sequencing technologies and the downstream bioinformatics analysis of the large quantities of sequence data generated by these technologies. The proposed Cold Spring Harbor Laboratory course on Advanced Sequencing Technologies & Bioinformatics Analysis is to be held November 2021-2025. A broad range of scientific questions are amenable to exploration through modern approaches in DNA/RNA sequence analysis, and we therefore anticipate applications from individuals working in areas across the biological and biomedical sciences, from evolution and development to plant and animal physiology to cancer and host response to infectious diseases. Students will be instructed in the detailed operation of several revolutionary sequencing platforms, including library construction procedures, general data processing, and in-depth data analysis. Common experimental approaches enabled by massively parallel sequencing technologies will be explored in detail, including de novo DNA sequencing and assembly of genomes, DNA re-sequencing of known cancer genes, bulk transcriptome profiling, single-cell transcriptome profiling, small variant discovery/interpretation and other approaches that are tailored to the student's research areas of interest. Expanding the bioinformatics component of the course, students will be introduced to Unix command-line, important file formats, alignment, data visualization, basic scripting in R, bash and other program languages, cluster job submission and bioinformatics pipeline development. Guest lecturers contribute to the course and are encouraged to highlight their own applications of these revolutionary technologies. This specialized training in a residential setting immediately impacts the progress of the trainees’ research, and promotes collaboration and exchange of ideas between faculty and trainees, and thus represents a significant and valuable investment towards accelerating genome research. The advanced scope of the course will be twinned with an innovative educational design, including the broader dissemination of the course lectures and associated material and problem sets via tailored online learning tools. Significant outreach to and engagement of all research communities and individuals will be combined with dedicated mentoring and follow-up to help retain and provide ongoing academic support of individuals with specific research interests that intersect with the scope of the course.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $80,019 )
2025	2025	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPG HBR	NY	11724	SUFFOLK	USA	Human Genome Research	000	14	9/9/2025	NON-COMPETING CONTINUATION	$80,019
														Subtotal = $80,019

Issue Date FY: 2024 ( Subtotal = $80,019 )
2024	2024	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPG HBR	NY	11724	SUFFOLK	USA	Human Genome Research	000	13	6/26/2024	NON-COMPETING CONTINUATION	$80,019
														Subtotal = $80,019

Issue Date FY: 2023 ( Subtotal = $80,019 )
2023	2023	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Human Genome Research	000	12	6/7/2023	NON-COMPETING CONTINUATION	$80,019
														Subtotal = $80,019

Issue Date FY: 2022 ( Subtotal = $80,019 )
2022	2022	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Human Genome Research	006	11	7/22/2022	NON-COMPETING CONTINUATION	$80,019
2022	2021	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Human Genome Research	001	10	11/29/2021	COMPETING CONTINUATION	$11,017
2022	2021	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Human Genome Research	005	10	5/3/2022	COMPETING CONTINUATION	$11,017
2022	2021	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Human Genome Research	003	10	11/29/2021	COMPETING CONTINUATION	-$11,017
2022	2020	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Human Genome Research	002	9	11/29/2021	NON-COMPETING CONTINUATION	$11,017
2022	2020	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Human Genome Research	000	9	11/29/2021	NON-COMPETING CONTINUATION	-$11,017
2022	2020	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Human Genome Research	004	9	5/3/2022	NON-COMPETING CONTINUATION	-$11,017
														Subtotal = $80,019

Issue Date FY: 2021 ( Subtotal = $80,019 )
2021	2021	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Human Genome Research	000	10	9/21/2021	COMPETING CONTINUATION	$80,019
														Subtotal = $80,019

Issue Date FY: 2020 ( Subtotal = $58,895 )
2020	2020	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Human Genome Research	000	9	6/11/2020	NON-COMPETING CONTINUATION	$58,895
														Subtotal = $58,895

Issue Date FY: 2019 ( Subtotal = $58,895 )
2019	2019	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Human Genome Research	001	8	6/26/2019	NON-COMPETING CONTINUATION	$58,895
2019	2017	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Human Genome Research	000	6	10/29/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $58,895

Issue Date FY: 2018 ( Subtotal = $58,895 )
2018	2018	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Human Genome Research	000	7	8/31/2018	COMPETING CONTINUATION	$58,895
														Subtotal = $58,895

Issue Date FY: 2017 ( Subtotal = $70,160 )
2017	2017	COLD SPRING HARBOR LABORATORY	1 BUNGTOWN RD	COLD SPRING HARBOR	NY	11724	SUFFOLK	USA	Human Genome Research	000	6	7/7/2017	NON-COMPETING CONTINUATION	$70,160
														Subtotal = $70,160

Issue Date FY: 2016 ( Subtotal = $70,160 )
2016	2016	COLD SPRING HARBOR LABORATORY	BUNGTOWN ROAD	COLD SPRING HRBR	NY	11724		USA	Human Genome Research	000	5	6/21/2016	NON-COMPETING CONTINUATION	$70,160
														Subtotal = $70,160

Issue Date FY: 2015 ( Subtotal = $70,160 )
2015	2015	COLD SPRING HARBOR LABORATORY	BUNGTOWN ROAD	COLD SPRING HRBR	NY	11724		USA	Human Genome Research	000	4	9/17/2015	COMPETING CONTINUATION	$70,160
														Subtotal = $70,160

Issue Date FY: 2014 ( Subtotal = $52,816 )
2014	2014	COLD SPRING HARBOR LABORATORY	BUNGTOWN ROAD	COLD SPRING HRBR	NY	11724		USA	Human Genome Research	000	3	3/25/2014	NON-COMPETING CONTINUATION	$52,816
														Subtotal = $52,816

Issue Date FY: 2013 ( Subtotal = $66,069 )
2013	2013	COLD SPRING HARBOR LABORATORY	BUNGTOWN ROAD	COLD SPRING HRBR	NY	11724		USA	Human Genome Research	000	2	6/5/2013	NON-COMPETING CONTINUATION	$52,855
2013	2013	COLD SPRING HARBOR LABORATORY	BUNGTOWN ROAD	COLD SPRING HRBR	NY	11724		USA	Human Genome Research	001	2	9/12/2013	SUPPLEMENT FOR EXPANSION	$13,214
														Subtotal = $66,069

Issue Date FY: 2012 ( Subtotal = $52,885 )
2012	2012	COLD SPRING HARBOR LABORATORY	BUNGTOWN ROAD	COLD SPRING HRBR	NY	11724		USA	Human Genome Research	000	1	4/9/2012	NEW	$52,885
														Subtotal = $52,885

Grand Total All Awards = $959,030

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CSHL Course on Advanced Sequencing Technologies & Bioinformatics Analysis

Award Number: R25HG006424

ORGANIZATION: NATIONAL HUMAN GENOME RESEARCH INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/10/2012

PERIOD OF PERFORMANCE END DATE: 06/30/2026

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