Friday, April 26, 2024 4/26/2024

Pacific High Schools STEP-UP to One Health

Award Number: R25DK078386
ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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PROJECT SUMMARY The John A. Burns School of Medicine of the University of Hawaii proposes to continue to develop the Pacific STEP-UP Program to provide research training and mentoring to underrepresented and disadvantaged high school students in the State of Hawaii, and the six US and US affiliated territories in the Pacific (Region E). For the past 5 years, Pacific STEP-UP has enrolled 104 students in the NIDDK STEP-UP summer program, and exposed other students to laboratory sciences during the school year. We continued to build capacity for laboratory research in the Pacific colleges where there was none before us. We tracked 375 STEP-UP alumni from as early as 2005 to find that a majority pursued college education with a science emphasis, and many also sought post-graduate training and terminal degrees. Pacific STEP-UP remains the only formalized hands- on research training program for high schools in the US Pacific, amid the urgent need to build and foster a pipeline of underrepresented individuals seeking health research careers in order to combat health disparity in this region of the world. With confidence that Pacific STEP-UP has established roots in the region, we will continue our research training and mentoring program but charting a new course under framework of One Health. The new strategy and approach in research training, mentoring, and in capacity building will further NIDDK STEP-UP’s reach into the Pacific communities by bringing awareness of the interdependency of the well beings of humans, animals, and the eco-environment; and its impact on health-related issues. The goal is to seed and shape a culture that values One Health research as the means to address pertinent health issues in these communities, and grow a cadre of “home-grown” scientists readied to research for solutions. In doing so, we will fulfill NIDDK’s STEP-UP mission to build and diversify a pipeline of future scientists interested in tackling health and disease questions related to NIDDK from multiple angles of trans-sectorial and trans- disciplinary approach under One Health. Accordingly, we propose three Specific Aims. (1). Recruit best qualified high school students (11th and 12th grade) from the seven US State and Territories in the Pacific into the STEP-UP Summer Research Program, and track the cohort’s academic progress for a minimum of 5 years. (2). Provide individualized research experience (and related education and training) that stresses One Health approach, and local community or population relevance. Provide STEP-UP alumni with follow up, and research-focused, mentoring extending for 9 months. (3). Seed and nurture interests in One Health in high school students while strengthening local colleges’ capacity to enable laboratory-, field-, and community-based research with a focus on One Health concepts, all in support of the Pacific STEP-UP program by expanding application pool and research opportunities, and strengthening the research training program.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $262,411 )
2024	2024	UNIVERSITY OF HAWAII	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	18	3/21/2024	NON-COMPETING CONTINUATION	$262,411
														Subtotal = $262,411

Issue Date FY: 2023 ( Subtotal = $291,567 )
2023	2023	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	003	17	3/30/2023	NON-COMPETING CONTINUATION	$291,567
2023	2022	UNIVERSITY OF HAWAII	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	16	1/4/2023	COMPETING CONTINUATION	$273,921
2023	2021	UNIVERSITY OF HAWAII	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	15	1/4/2023	NON-COMPETING CONTINUATION	-$263,357
2023	2020	UNIVERSITY OF HAWAII	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	14	1/4/2023	SUPPLEMENT FOR EXPANSION	-$10,564
														Subtotal = $291,567

Issue Date FY: 2022 ( Subtotal = $291,567 )
2022	2022	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	16	4/26/2022	COMPETING CONTINUATION	$291,567
2022	2021	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	15	4/18/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $291,567

Issue Date FY: 2021 ( Subtotal = $220,266 )
2021	2021	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	15	2/18/2021	NON-COMPETING CONTINUATION	$220,266
														Subtotal = $220,266

Issue Date FY: 2020 ( Subtotal = $274,266 )
2020	2020	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	14	2/7/2020	NON-COMPETING CONTINUATION	$220,266
2020	2020	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	14	8/3/2020	SUPPLEMENT FOR EXPANSION	$54,000
														Subtotal = $274,266

Issue Date FY: 2019 ( Subtotal = $220,266 )
2019	2019	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	13	1/30/2019	NON-COMPETING CONTINUATION	$220,266
														Subtotal = $220,266

Issue Date FY: 2018 ( Subtotal = $220,266 )
2018	2018	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	12	4/19/2018	NON-COMPETING CONTINUATION	$22,027
2018	2018	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	12	2/14/2018	NON-COMPETING CONTINUATION	$198,239
														Subtotal = $220,266

Issue Date FY: 2017 ( Subtotal = $220,266 )
2017	2017	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	11	2/23/2017	COMPETING CONTINUATION	$164,376
2017	2017	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	004	11	7/7/2017	COMPETING CONTINUATION	$39,761
2017	2017	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	11	3/30/2017	SUPPLEMENT FOR EXPANSION	$55,890
2017	2016	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	003	10	7/7/2017	EXTENSION WITH OR WITHOUT FUNDS	-$39,761
2017	2016	UNIVERSITY OF HAWAII SYSTEMS	2425 CAMPUS RD SINCLAIR RM 1	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	10	2/20/2017	EXTENSION WITH OR WITHOUT FUNDS	$0
														Subtotal = $220,266

Issue Date FY: 2016 ( Subtotal = $236,265 )
2016	2016	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	10	2/18/2016	EXTENSION WITH OR WITHOUT FUNDS	$236,265
														Subtotal = $236,265

Issue Date FY: 2015 ( Subtotal = $236,265 )
2015	2015	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	9	2/16/2015	NON-COMPETING CONTINUATION	$236,265
														Subtotal = $236,265

Issue Date FY: 2014 ( Subtotal = $236,265 )
2014	2014	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	8	2/28/2014	NON-COMPETING CONTINUATION	$205,161
2014	2014	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	8	3/10/2014	SUPPLEMENT FOR EXPANSION	$31,104
														Subtotal = $236,265

Issue Date FY: 2013 ( Subtotal = $197,980 )
2013	2013	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	7	2/21/2013	NON-COMPETING CONTINUATION	$184,645
2013	2013	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	7	5/20/2013	NON-COMPETING CONTINUATION	$13,335
														Subtotal = $197,980

Issue Date FY: 2012 ( Subtotal = $205,161 )
2012	2012	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	001	6	3/19/2012	COMPETING CONTINUATION	$205,161
2012	2011	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	5	3/14/2012	NON-COMPETING CONTINUATION	$0
														Subtotal = $205,161

Issue Date FY: 2011 ( Subtotal = $178,901 )
2011	2011	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	5	3/22/2011	NON-COMPETING CONTINUATION	$161,011
2011	2011	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	002	5	6/2/2011	NON-COMPETING CONTINUATION	$17,890
2011	2010	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Trans-NIH Recovery Act Research Support	001	4	4/22/2011	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $178,901

Issue Date FY: 2010 ( Subtotal = $632,305 )
2010	2010	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Kidney Diseases, Urology and Hematology Research	000	4	3/23/2010	NON-COMPETING CONTINUATION	$178,901
2010	2010	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Trans-NIH Recovery Act Research Support	001	4	5/21/2010	SUPPLEMENT FOR EXPANSION	$453,404
														Subtotal = $632,305

Issue Date FY: 2009 ( Subtotal = $333,773 )
2009	2009	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Trans-NIH Recovery Act Research Support	001	3	7/14/2009	SUPPLEMENT FOR EXPANSION	$154,872
2009	2009	UNIVERSITY OF HAWAII	2530 Dole St., Sakamaki D200	HONOLULU	HI	96822	HONOLULU	USA	Kidney Diseases, Urology and Hematology Research	000	3	3/16/2009	NON-COMPETING CONTINUATION	$178,901
														Subtotal = $333,773

Issue Date FY: 2008 ( Subtotal = $280,130 ) (Continued on the next page)
Grand Total All Awards = $4,720,472

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Pacific High Schools STEP-UP to One Health

Award Number: R25DK078386

ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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