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CaNCURE: Cancer Nanomedicine Co-ops for Undergraduate Research Experiences

Award Number: R25CA174650
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/18/2014
PERIOD OF PERFORMANCE END DATE: 06/30/2029

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CaNCURE: Cancer Nanomedicine Co-ops for Undergraduate Research Experiences - CaNCURE: Cancer Nanomedicine Co-ops for Undergraduate Research Experiences was created by Northeastern University (NEU) and Dana-Farber/Harvard Cancer Center (DF/HCC) to provide immersive research training and education at the interface of nanotechnology, cancer biology, and medicine to attract, retain, and encourage young scientists and engineers to pursue careers in cancer research. The central hypothesis of CaNCURE is that a 6-month, full-time, mentored research experience, accompanied by a rich educational environment providing intellectual immersion in cancer nanomedicine, will lead to persistence in college and motivation for a career in cancer research. With the support of two consecutive NCI R25 awards (2014-24), the CaNCURE program has provided 6-month mentored research experiences for 133 students from 14 different STEM disciplines. Trainees conducted high-impact research in 43 NCI-funded laboratories, published 67 peer- reviewed manuscripts in high-impact cancer and nanomedicine journals, and won 68 research awards. 67% of trainees continued to volunteer in their CaNCURE lab after co-op completion and 36% went on to complete one or more additional cancer research experiences before graduation. Of the 109 students who graduated, 38% went to medical school, 16% went to graduate school, and 40% pursued research careers in the healthcare field. 23 more undergraduates will complete this program by June 2024. Here we seek to renew and expand the CaNCURE program to train 85 new undergraduates during 2024-2029. Traineeships will be provided to 17 students per year spread across 2 co-op cycles (January-June and July-December). To further strengthen the existing program, we propose the addition of 11 new faculty mentors aligned with the NCI’s 2024 strategic goals, formal mentor training, hands-on research training workshops, small-group patient case study discussions, and a CaNCURE advising system to support trainee research efforts after the co-op. The program will achieve its goals through the following specific aims: Specific Aim 1: Provide a hands-on, full-time research experience with a focus in cancer nanomedicine mentored by world-class cancer researchers at NEU and DF/HCC. Specific Aim 2: Provide year-round activities for training enrichment, including weekly seminars, patient case studies, hands-on research training, a reflective e-portfolio, and conference travel. Specific Aim 3: Provide professional preparation for a career in cancer research, including professional skills training, opportunities to network and present research, and resources to enhance career preparation both during and after co-op.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $308,168 )
2025	2025	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	001	12	5/12/2025	NON-COMPETING CONTINUATION	$308,168
2025	2023	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	000	10	2/28/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $308,168

Issue Date FY: 2024 ( Subtotal = $309,009 )
2024	2024	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	000	11	3/7/2024	COMPETING CONTINUATION	$309,009
														Subtotal = $309,009

Issue Date FY: 2023 ( Subtotal = $217,428 )
2023	2023	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	000	10	6/14/2023	NON-COMPETING CONTINUATION	$217,428
														Subtotal = $217,428

Issue Date FY: 2022 ( Subtotal = $273,990 )
2022	2022	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	000	9	8/1/2022	NON-COMPETING CONTINUATION	$273,990
														Subtotal = $273,990

Issue Date FY: 2021 ( Subtotal = $273,958 )
2021	2021	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	001	8	6/30/2021	NON-COMPETING CONTINUATION	$257,958
2021	2021	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	002	8	8/26/2021	NON-COMPETING CONTINUATION	$16,000
2021	2020	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	000	7	1/12/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $273,958

Issue Date FY: 2020 ( Subtotal = $268,081 )
2020	2020	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	002	7	6/30/2020	NON-COMPETING CONTINUATION	$268,081
2020	2019	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	001	6	1/28/2020	COMPETING CONTINUATION	$6,466
2020	2018	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	000	5	1/28/2020	NON-COMPETING CONTINUATION	-$6,466
														Subtotal = $268,081

Issue Date FY: 2019 ( Subtotal = $275,281 )
2019	2019	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	000	6	2/26/2019	COMPETING CONTINUATION	$275,281
														Subtotal = $275,281

Issue Date FY: 2018 ( Subtotal = $230,781 )
2018	2018	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	000	5	8/23/2018	NON-COMPETING CONTINUATION	$230,781
														Subtotal = $230,781

Issue Date FY: 2017 ( Subtotal = $230,781 )
2017	2017	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	000	4	6/23/2017	NON-COMPETING CONTINUATION	$230,781
														Subtotal = $230,781

Issue Date FY: 2016 ( Subtotal = $225,974 )
2016	2016	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVENUE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	000	3	6/27/2016	NON-COMPETING CONTINUATION	$225,974
														Subtotal = $225,974

Issue Date FY: 2015 ( Subtotal = $230,880 )
2015	2015	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVENUE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	000	2	6/5/2015	NON-COMPETING CONTINUATION	$230,880
														Subtotal = $230,880

Issue Date FY: 2014 ( Subtotal = $232,682 )
2014	2014	NORTHEASTERN UNIVERSITY	360 HUNTINGTON AVENUE	BOSTON	MA	02115	SUFFOLK	USA	Cancer Research Manpower	000	1	7/18/2014	NEW	$232,682
														Subtotal = $232,682

Grand Total All Awards = $3,077,013

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CaNCURE: Cancer Nanomedicine Co-ops for Undergraduate Research Experiences

Award Number: R25CA174650

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/18/2014

PERIOD OF PERFORMANCE END DATE: 06/30/2029

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