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Tri-I Training Program in Metabolomics

Award Number: R25AI140472
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/01/2019
PERIOD OF PERFORMANCE END DATE: 08/31/2030

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Tri-I Training Program in Metabolomics - PROJECT SUMMARY/ABSTRACT Metabolomics has emerged as the newest systems-level discipline with demonstrated potential to provide mechanistic insights in the fields of infectious disease, microbiome science, inflammation, and immunology. However, a key barrier to this potential is the conceptually and technologically unique nature of metabolomics that distinguishes it from other systems level disciplines. This proposal seeks to continue to deliver and expand an established structured didactic and laboratory training program aimed at increasing both the conceptual and technological accessibility of metabolomics to NIAID-funded trainees. This program combines multiple educational activities tiered to maximize adoption and competence in advanced metabolomics techniques and equip trainees with both theoretical and practical understanding of these emerging technologies. This will be achieved through 3 complementary activities: Activity 1 is a didactic course accompanied by data analysis exercises developed to emphasize key concepts in both modern mass spectrometry, NMR analysis and the implementation of these approaches in biomedical research. In this renewal application, we will expand the mentored data analysis exercises and we will continue to refine and update this content to include emerging technologies and experimental approaches. Activity 2 is a mentored project development clinic aimed in which participants can develop ideas originating from their own research into actionable, well-controlled experiments – here, the emphasis is on recognizing the strengths and weaknesses of the available technologies, rigorous experimental design, and developing appropriate data analysis strategies. Activity 3 of the program consists of tailored, mentored laboratory research experiences allowing trainees to develop skills specifically aligned with their research objectives – this may constitute a series of small pilot experiments, the development or implementation of a new method, or refining an existing analytical strategy to better address their research question. Although these activities will frequently be accessed sequentially, our program will continue to support these modules being accessed independently. This further allows this program to deliver training, mentorship, and research experiences in a format that meets the individual trainee needs and their differing career stages. In this renewal application, we are also recruiting from NIAID-supported labs at all NY metro area research institutions to further expand the biomedical workforce in this discipline and will initiate a mechanism for disseminating program content via the existing online infrastructure at Cold Spring Harbor Laboratory.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $374,698 )
2026	2026	WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY	575 LEXINGTON AVE FL 9	NEW YORK	NY	10022	NEW YORK	USA	Allergy and Infectious Diseases Research	001	7	8/11/2026	NON-COMPETING CONTINUATION	$374,698
2026	2023	WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY	575 LEXINGTON AVE FL 9	NEW YORK	NY	10022	NEW YORK	USA	Allergy and Infectious Diseases Research	000	5	4/6/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $374,698

Issue Date FY: 2025 ( Subtotal = $380,000 )
2025	2025	WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY	575 LEXINGTON AVE FL 9	NEW YORK	NY	10022	NEW YORK	USA	Allergy and Infectious Diseases Research	000	6	9/8/2025	COMPETING CONTINUATION	$380,000
														Subtotal = $380,000

Issue Date FY: 2023 ( Subtotal = $325,814 )
2023	2023	WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY	1300 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	Allergy and Infectious Diseases Research	001	5	7/20/2023	NON-COMPETING CONTINUATION	$325,814
2023	2022	WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY	1300 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	Allergy and Infectious Diseases Research	000	4	5/2/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $325,814

Issue Date FY: 2022 ( Subtotal = $327,592 )
2022	2022	WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY	1300 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	Allergy and Infectious Diseases Research	000	4	7/21/2022	NON-COMPETING CONTINUATION	$327,592
														Subtotal = $327,592

Issue Date FY: 2021 ( Subtotal = $329,334 )
2021	2021	WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY	1300 YORK AVE	NEW YORK	NY	10065	NEW YORK	USA	Allergy and Infectious Diseases Research	000	3	7/30/2021	NON-COMPETING CONTINUATION	$329,334
														Subtotal = $329,334

Issue Date FY: 2020 ( Subtotal = $331,042 )
2020	2020	WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY	407 E 61ST ST RM 106 1ST FL	NEW YORK	NY	10065	NEW YORK	USA	Allergy and Infectious Diseases Research	000	2	8/11/2020	NON-COMPETING CONTINUATION	$331,042
														Subtotal = $331,042

Issue Date FY: 2019 ( Subtotal = $334,714 )
2019	2019	WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY	407 E 61ST ST RM 106 1ST FL	NEW YORK	NY	10065	NEW YORK	USA	Allergy and Infectious Diseases Research	000	1	7/31/2019	NEW	$334,714
														Subtotal = $334,714

Grand Total All Awards = $2,403,194

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Tri-I Training Program in Metabolomics

Award Number: R25AI140472

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/01/2019

PERIOD OF PERFORMANCE END DATE: 08/31/2030

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