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OLD WESTBURY NEUROSCIENCE RESEARCH INSTITUTE MIDARP

Award Number: R24DA009010
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 12/01/1996
PERIOD OF PERFORMANCE END DATE: 05/31/2009

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OLD WESTBURY NEUROSCIENCE RESEARCH INSTITUTE MIDARP - DESCRIPTION (provided by applicant): The goals of the proposed continuing Minority Institutions' Drug Abuse Research Development Program (MIDARP) at Old Westbury Neuroscience Research Institute (OWNRI) are (1) to conduct studies in the areas of substance abuse, (2) to increase minority representation and faculty development in the fields of neuroscience neuroimmunology and drug abuse by providing a state-of-the-art research experience and associated activities, e.g., seminars, lectures, etc., to new faculty and students, and (3) to disseminate findings through scholarly publications, presentations and workshops. The College at Old Westbury is ideally suited to carry out this mission since its faculty are developing expertise in substance abuse as demonstrated by their peer-reviewed publications. Furthermore, in its previous period of funding, the Old Westbury MIDARP discovered a novel opiate receptor subtype, designated mu3, that is opiate alkaloid selective and opioid peptide insensitive. The program has a multi-ethnic faculty and a high percentage of minority students that choose science as a major with drug abuse interests. The faculty have special interests in molecular and cellular neuroimmunology related to the National Institute on Drug Abuse priorities, e.g., endogenous morphine and opiate induced immune downregulation. The proposed research program plans to develop greater program expertise in molecular biology. Additionally, it proposes to add a new faculty with NIDA interests. As part of its infrastructure-building activities, scientists from major research organizations will be invited to give lectures on relevant topics. Undergraduate and graduate students will be employed as research assistants. The major research projects incorporated into this proposal are designed to address two of NIDA's priorities: 1) Determining the process of morphine biosynthesis, including the identification of morphine precursors and enzymes; and 2) Determining the signal transduction pathway, gene and protein expression of the mu3 opiate receptor in various conditions and how it is related to drug addiction, and to clone, sequence, and study the function of the new mu4 gene.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2008 ( Subtotal = $364,935 )
2008	2008	SUNY COLLEGE, OLD WESTBURY	POST OFFICE BOX 210	OLD WESTBURY	NY	11568	NASSAU	USA	Drug Use and Addiction Research Programs	000	18	5/20/2008	NON-COMPETING CONTINUATION	$364,935
														Subtotal = $364,935

Issue Date FY: 2007 ( Subtotal = $373,694 )
2007	2007	SUNY COLLEGE, OLD WESTBURY	POST OFFICE BOX 210	OLD WESTBURY	NY	11568	NASSAU	USA	Drug Use and Addiction Research Programs	000	17	5/23/2007	NON-COMPETING CONTINUATION	$373,694
														Subtotal = $373,694

Issue Date FY: 2006 ( Subtotal = $385,868 )
2006	2006	SUNY COLLEGE, OLD WESTBURY	POST OFFICE BOX 210	OLD WESTBURY	NY	11568	NASSAU	USA	Drug Use and Addiction Research Programs	000	16	5/24/2006	NON-COMPETING CONTINUATION	$385,868
														Subtotal = $385,868

Issue Date FY: 2005 ( Subtotal = $386,440 )
2005	2005	SUNY COLLEGE, OLD WESTBURY	POST OFFICE BOX 210	OLD WESTBURY	NY	11568	NASSAU	USA	Drug Use and Addiction Research Programs	000	15	5/27/2005	NON-COMPETING CONTINUATION	$386,440
														Subtotal = $386,440

Issue Date FY: 2004 ( Subtotal = $369,073 )
2004	2004	SUNY COLLEGE, OLD WESTBURY	POST OFFICE BOX 210	OLD WESTBURY	NY	11568	NASSAU	USA	Drug Use and Addiction Research Programs	000	14	6/18/2004	COMPETING CONTINUATION	$369,073
														Subtotal = $369,073

Issue Date FY: 2003 ( Subtotal = $363,756 )
2003	2003	SUNY COLLEGE, OLD WESTBURY	POST OFFICE BOX 210	OLD WESTBURY	NY	11568	NASSAU	USA	Drug Use and Addiction Research Programs	000	13		NON-COMPETING CONTINUATION	$363,756
														Subtotal = $363,756

Issue Date FY: 2002 ( Subtotal = $401,816 )
2002	2002	SUNY COLLEGE, OLD WESTBURY	POST OFFICE BOX 210	OLD WESTBURY	NY	11568	NASSAU	USA	Drug Use and Addiction Research Programs	000	12	12/7/2001	NON-COMPETING CONTINUATION	$401,816
														Subtotal = $401,816

Issue Date FY: 2001 ( Subtotal = $424,022 )
2001	2001	SUNY COLLEGE, OLD WESTBURY	POST OFFICE BOX 210	OLD WESTBURY	NY	11568	NASSAU	USA	Drug Use and Addiction Research Programs	000	11	12/12/2000	NON-COMPETING CONTINUATION	$424,022
														Subtotal = $424,022

Issue Date FY: 2000 ( Subtotal = $433,853 )
2000	2000	SUNY COLLEGE, OLD WESTBURY	POST OFFICE BOX 210	OLD WESTBURY	NY	11568	NASSAU	USA	Drug Use and Addiction Research Programs	000	10	12/1/1999	NON-COMPETING CONTINUATION	$433,853
														Subtotal = $433,853

Issue Date FY: 1999 ( Subtotal = $420,716 )
1999	1999	SUNY COLLEGE, OLD WESTBURY	POST OFFICE BOX 210	OLD WESTBURY	NY	11568	NASSAU	USA	Drug Use and Addiction Research Programs	000	9	5/10/1999	COMPETING CONTINUATION	$260,312
1999	1999	SUNY COLLEGE, OLD WESTBURY	POST OFFICE BOX 210	OLD WESTBURY	NY	11568	NASSAU	USA	Drug Use and Addiction Research Programs	002	9	7/13/1999	SUPPLEMENT FOR EXPANSION	$28,941
1999	1999	SUNY COLLEGE, OLD WESTBURY	POST OFFICE BOX 210	OLD WESTBURY	NY	11568	NASSAU	USA	Drug Use and Addiction Research Programs	001	9	5/26/1999	SUPPLEMENT FOR EXPANSION	$19,749
1999	1999	SUNY COLLEGE, OLD WESTBURY	POST OFFICE BOX 210	OLD WESTBURY	NY	11568	NASSAU	USA	Drug Use and Addiction Research Programs	001	8	2/17/1999	SUPPLEMENT FOR EXPANSION	$111,714
														Subtotal = $420,716

Issue Date FY: 1998 ( Subtotal = $354,583 )
1998	1998	SUNY COLLEGE, OLD WESTBURY	POST OFFICE BOX 210	OLD WESTBURY	NY	11568	NASSAU	USA	Drug Use and Addiction Research Programs	000	8	11/24/1997	NON-COMPETING CONTINUATION	$354,583
														Subtotal = $354,583

Grand Total All Awards = $4,278,756

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OLD WESTBURY NEUROSCIENCE RESEARCH INSTITUTE MIDARP

Award Number: R24DA009010

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 12/01/1996

PERIOD OF PERFORMANCE END DATE: 05/31/2009

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