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Tailoring Recruitment Communication using Virtual Human Technology to Increase Participation of Older Minority Adults in Clinical Trials

Award Number: R24AG074867
ORGANIZATION: NATIONAL INSTITUTE ON AGING
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Tailoring Recruitment Communication using Virtual Human Technology to Increase Participation of Older Minority Adults in Clinical Trials - PROJECT SUMMARY Older adult minorities are an underserved population, who are at a particularly high risk for developing chronic diseases/health conditions and are significantly underrepresented in clinical research. Well-known barriers, including research-related mistrust (e.g., belief that participants lack choice, mistrust of white researchers), lack of cultural diversity/sensitivity among CT staff, and the exclusion of decisional support providers in decision- making impede older adult minority participation in CTs. Tailoring content and source preferences to be patient- centered, culturally sensitive (i.e., promote feelings of comfort, trust, respect), and personally relevant to the receiver (a patient), thus increasing the likelihood of having a lasting effect on their attitudes and behaviors, has been linked to positive health behaviors by older adult minorities. Such tailoring has not been studied to increase participation rates of older adult minorities into active CTs, though culturally tailored VHT interventions are perceived as trustworthy among minority participants. Our long-term goal is to increase clinical trial (CT) participation among older adult minorities (Black/African American (AA), Hispanic/Latinx (H/L), and/or rural adults over the age of 50) using Virtual Human Technology (VHT). In Aim1, we will conduct focus groups with older adult minorities to obtain data that will be used to redesign ALEX to be culturally sensitive for these minorities. In Aim 2, track engagement of such minorities into active, NIH-funded CTs across different modalities for remotely delivering ALEX. In Aim 3, we will compare ALEX and standard recruitment methods for enrolling such minorities into NIH-funded CTs. Achievement of these project aims will result in adaptable, minimally tailored VHT recruitment intervention for increasing older adult minority participation rates in active NIH-funded CTs.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2023	UNIVERSITY OF FLORIDA	1523 UNION RD RM 207	GAINESVILLE	FL	32611	ALACHUA	USA	Aging Research	001	3	2/26/2025	NON-COMPETING CONTINUATION	-$1
2025	2023	MAYO CLINIC JACKSONVILLE (A NONPROFIT CORPORATION)	4500 SAN PABLO RD S	JACKSONVILLE	FL	32224	DUVAL	USA	Aging Research	002	4	2/26/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$688,679
2025	2022	UNIVERSITY OF FLORIDA	1523 UNION RD RM 207	GAINESVILLE	FL	32611	ALACHUA	USA	Aging Research	000	2	2/26/2025	NON-COMPETING CONTINUATION	-$688,678
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = -$130,702 )
2024	2023	MAYO CLINIC JACKSONVILLE (A NONPROFIT CORPORATION)	4500 SAN PABLO RD S	JACKSONVILLE	FL	32224	DUVAL	USA	Aging Research	001	4	4/5/2024	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$561,112
2024	2023	UNIVERSITY OF FLORIDA	1523 UNION RD RM 207	GAINESVILLE	FL	32611	ALACHUA	USA	Aging Research	000	3	4/4/2024	NON-COMPETING CONTINUATION	-$691,814
														Subtotal = -$130,702

Issue Date FY: 2023 ( Subtotal = $691,815 )
2023	2023	UNIVERSITY OF FLORIDA	1523 UNION RD RM 207	GAINESVILLE	FL	32611	ALACHUA	USA	Aging Research	000	3	8/15/2023	NON-COMPETING CONTINUATION	$691,815
														Subtotal = $691,815

Issue Date FY: 2022 ( Subtotal = $714,158 )
2022	2022	UNIVERSITY OF FLORIDA	1523 UNION RD RM 207	GAINESVILLE	FL	32611	ALACHUA	USA	Aging Research	000	2	7/29/2022	NON-COMPETING CONTINUATION	$714,158
														Subtotal = $714,158

Issue Date FY: 2021 ( Subtotal = $761,311 )
2021	2021	UNIVERSITY OF FLORIDA	1523 UNION RD RM 207	GAINESVILLE	FL	32611	ALACHUA	USA	Aging Research	000	1	9/21/2021	NEW	$761,311
														Subtotal = $761,311

Grand Total All Awards = $2,036,582

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Tailoring Recruitment Communication using Virtual Human Technology to Increase Participation of Older Minority Adults in Clinical Trials

Award Number: R24AG074867

ORGANIZATION: NATIONAL INSTITUTE ON AGING

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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