Friday, April 4, 2025
4/4/2025
Roybal Resource and Coordinating Center to Accelerate Translational Aging Research - PROJECT SUMMARY The overall goal of this Northwell Roybal Coordinating Center to Accelerate Translational Aging Research (RCC) is to provide strategic leadership, efficient coordination, effective training, and proactive dissemination for the Edward R. Roybal Centers. We will support Roybal program scientists as they conduct translational behavioral and social intervention development research relevant to aging and AD/ADRD. Roybal scientists will advance progress on translational research priorities through the conduct of clinical trials in Stages 0 through V of the NIH Stage Model for Behavioral Intervention Development. We will provide critical infrastructure for Roybal Centers to conduct and disseminate scalable, principle-defined behavioral interventions that promote healthy aging and address the burden of AD/ADRD at multiple societal levels. We will serve as the hub to facilitate and coordinate trans-Roybal activities, and reinforce the goals of the NIH Stage Model by: 1) providing centralized administrative support; 2) creating mechanisms for maintaining actively engaged sites; 3) promoting educational and training opportunities; 4) disseminating scientific advances to all stakeholders; and 5) evaluating the success of the Roybal program in achieving its agreed-upon goals. The RCC will serve as the central resource to: 1) share best practices, and ensure scientific integrity and patient safety for Roybal trials through a centralized Data and Safety Monitoring Board (DSMB); 2) coordinate a centralized annual Roybal national competition for new trials; 3) host annual meetings; 4) identify joint activities; 5) disseminate study findings and accomplishments to broad and diverse audiences; and 6) evaluate metrics in achieving program goals. This will be accomplished through a close collaboration with NIA program officers, Roybal Centers, and other NIA-supported centers and programs. We will leverage and expand upon existing resources, data management systems, and partnerships to conduct activities that enhance the reach and impact of the Roybal Centers. Our primary long-term objective is the realization of Roybal scientists’ scientific productivity, as operationalized by the number of peer-reviewed publications and by the number of independent grants and contract awards funding NIH stage-informed trials that result from Roybal initial funding. Our secondary outcome is the visibility of our Roybal scientists’ impact. We will measure visibility through publication citations, mainstream media impressions, website visits, and social media shares. We intend that the products of these efforts will offer critical research infrastructure to advance progress on translational research priorities in accordance with the NIH Stage Model, foster collaboration, and disseminate to a broad and diverse audience the impact of Roybal scientists.
HHS’ Tracking Accountability in Government Grants System (TAGGS) website provides access to detailed descriptions of grants, loans, aggregated direct payments and other types of financial assistance awarded by the HHS Operating Divisions (OPDIVs) and the Office of the Secretary Staff Divisions (STAFFDIVs).