A New Foundation: Advancing Adolescent Neglect Science through Measurement Development - PROJECT SUMMARY The neglect of children and adolescents, a form of maltreatment along with abuse, is a significant problem that impairs health and well-being throughout the lifespan. The long-term goal of this exploratory/developmental research grant (R21) is to lay the groundwork for a larger research grant (R01) to examine the multilevel antecedents of adolescent neglect, information that is critical to the development of interventions. The objective is to conceptualize, develop and initially validate a multidimensional youth self- reported measure of adolescent neglect. Neglect is conceptualized as inadequately met adolescent needs that present actual or potential harm. This shifts from previous definitions which have focused on parental omissions in care. This adolescent-centered conceptualization helps reconcile neglect's definition with growing scientific evidence of its complex multilevel etiology. By untangling unmet needs from parental omissions, the adolescent-centered conceptualization allows for more rigorous research examining neglect's multilevel antecedents. Importantly, it offers a more constructive frame that should improve parent and youth engagement in intervention. Aim 1 is to conceptualize, develop and pilot test a youth self-report measure of adolescent neglect, defining it as critical unmet adolescent needs. It will apply rigorous qualitative methods per state-of-the-art Patient-Reported Outcome Measurement Information System (PROMIS) scientific standards for establishing content validity. Guided by an initial conceptual framework, this will include a scoping literature review, a two-round modified Delphi expert panel (N = 12) and cognitive and concept elicitation interviews with adolescents (N = 18). The second aim is to establish initial psychometric properties of the new neglect measure. We will explore the measure's dimensional structure and assess its reliability (internal consistency, test-retest), validity (criterion, concurrent and predictive convergent), and invariance in a sample of 12-17-year- olds in Philadelphia who are at risk for neglect (N = 400). The outcome of the proposed research will be a rigorously developed, novel measure of adolescent neglect with a sound conceptualization that incorporates input from diverse experts and youths (Aim 1) and evidence of psychometric properties (Aim 2). The measure has the potential for significant impact, paving the way for a new generation of neglect scholarship with a sound conceptual and operational basis that will illuminate the scope, multi-level contributors, and sequelae of adolescent neglect, informing policy and intervention that can overcome this intractable and pernicious problem.