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Home therapy for upper limb stroke rehabilitation using the HandSOME exoskeleton

Award Number: R21HD088783
ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/01/2016
PERIOD OF PERFORMANCE END DATE: 08/31/2019

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Home therapy for upper limb stroke rehabilitation using the HandSOME exoskeleton - There are 800,000 new strokes in the United States each year. Functional improvement of the upper paretic limb after stroke is mainly determined by improvement of the paretic hand, yet restoration of hand function after stroke often lags behind restoration of more proximal joints, and impairments are often resistant to therapeutic intervention. The rationale for our approach stems from the growing evidence that neuro-rehabilitation after stroke may be enhanced via the application of motor learning strategies within the context of repetitive movement practice. The key therapeutic aspects of these strategies are high repetition, volitional effort, and successful completion of tasks to prevent frustration. While these represent promising therapeutic strategies, they are limited to mildly impaired subjects who already have enough control of finger extension to tolerate high repetitions of grasp/release tasks without succumbing to fatigue and frustration. There is a very large population of stroke patients who don't fall into this category and often must rely on inefficient compensatory strategies. In these patients, unassisted repetitive task practice may not be the optimal retraining strategy. Previously we have developed HandSOME (Hand Spring Operated Movement Enabler), a passive exoskeleton that provides extension assistance during a simple grasp pattern. HandSOME is inexpensive, lightweight and can be donned independently by patients. Hand range-of-motion and function is increased immediately when wearing HandSOME and enables successful practice of reach and grasp tasks, even in subjects with severe hand impairment. The specific aims of this study are to make several protocol improvements based on our experiences from pilot testing to improve retention and evaluate this new protocol in a home training study with chronic stroke subjects.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2020 ( Subtotal = $0 )
2020	2017	CATHOLIC UNIVERSITY OF AMERICA (THE)	620 MICHIGAN AVE NE	WASHINGTON	DC	20064	DISTRICT OF COLUMBIA	USA	Child Health and Human Development Extramural Research	000	2	3/18/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2017 ( Subtotal = $226,659 )
2017	2017	CATHOLIC UNIVERSITY OF AMERICA (THE)	620 MICHIGAN AVE NE	WASHINGTON	DC	20064	DISTRICT OF COLUMBIA	USA	Child Health and Human Development Extramural Research	000	2	8/29/2017	NON-COMPETING CONTINUATION	$226,659
														Subtotal = $226,659

Issue Date FY: 2016 ( Subtotal = $189,648 )
2016	2016	CATHOLIC UNIVERSITY OF AMERICA	620 MICHIGAN AVE. N. E.	WASHINGTON	DC	20064	DISTRICT OF COLUMBIA	USA	Child Health and Human Development Extramural Research	000	1	8/17/2016	NEW	$189,648
														Subtotal = $189,648

Grand Total All Awards = $416,307

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Home therapy for upper limb stroke rehabilitation using the HandSOME exoskeleton

Award Number: R21HD088783

ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/01/2016

PERIOD OF PERFORMANCE END DATE: 08/31/2019

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