Sunday, December 21, 2025 12/21/2025

Generation of a new model for Usher syndrome.

Award Number: R21EY035834
ORGANIZATION: NATIONAL EYE INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 02/01/2024
PERIOD OF PERFORMANCE END DATE: 01/31/2027

Group Awards By:

View Award Description

Generation of a new model for Usher syndrome. - Summary Mutations in USH2A (usherin) are common causes of autosomal recessive blinding diseases in non-syndromic retinitis pigmentosa as well as syndromic Usher syndrome type II that manifests congenital hearing loss as well. There is no effective therapy for these diseases. How usherin contributes to photoreceptor health is poorly understood. An usherin-deficient animal model that exhibits severe retinal degeneration as in human patients is essential for understanding the pathological mechanisms and for development of effective therapies to preserve or restore vision. This project is aimed at generating an usherin-deficient model that recapitulates the phenotypes found in human patients.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2025	RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, THE	750 E ADAMS ST	SYRACUSE	NY	13210	ONONDAGA	USA	Vision Research	000	2	12/9/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $203,750 )
2025	2025	RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, THE	750 E ADAMS ST	SYRACUSE	NY	13210	ONONDAGA	USA	Vision Research	000	2	2/14/2025	NON-COMPETING CONTINUATION	$203,750
														Subtotal = $203,750

Issue Date FY: 2024 ( Subtotal = $244,500 )
2024	2024	RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, THE	750 E ADAMS ST	SYRACUSE	NY	13210	ONONDAGA	USA	Vision Research	000	1	1/18/2024	NEW	$244,500
														Subtotal = $244,500

Grand Total All Awards = $448,250

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Generation of a new model for Usher syndrome.

Award Number: R21EY035834

ORGANIZATION: NATIONAL EYE INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 02/01/2024

PERIOD OF PERFORMANCE END DATE: 01/31/2027

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer