Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

Dietary regulation of sleep in a blood-feeding insect

Award Number: R21AI191166
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 02/13/2026
PERIOD OF PERFORMANCE END DATE: 01/31/2028

Group Awards By:

View Award Description

Dietary regulation of sleep in a blood-feeding insect - Proposal Summary Neural regulation of sleep, appetite and energy homeostasis is critical to an animal’s survival and under stringent evolutionary pressure. Despite the prevalence of disorders associated with metabolism and sleep, the neural and genetic processes that regulate interactions between these two systems is unclear. This proposal will investigate how sleep is regulated by blood feeding in the disease vector mosquito Aedes aegypti. We will systematically define sleep in mosquitos, and determine the dietary amino acids that promote sleep. We will then screen neuropeptides for regulators of sleep to test for neuromodulators required for sleep following a blood meal. These experiments leverage decades of sleep analysis in fruit flies, to define sleep in a blood feeding insect. The findings have potential to identify conserved regulators of sleep-feeding interactions, as well as providing the first investigation of how macronutrients regulate sleep in a blood-feeding insect. Further, the methodology used to define sleep can be readily applied to other mosquito species. Therefore, the completion of this work will establish Ae. aegypti as a model for studying dietary regulation of sleep.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $411,704 )
2026	2026	TEXAS A & M UNIVERSITY	400 HARVEY MITCHELL PKY S STE 300	COLLEGE STATION	TX	77845	BRAZOS	USA	Allergy and Infectious Diseases Research	000	1	2/13/2026	NEW	$411,704
														Subtotal = $411,704

Grand Total All Awards = $411,704

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Dietary regulation of sleep in a blood-feeding insect

Award Number: R21AI191166

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 02/13/2026

PERIOD OF PERFORMANCE END DATE: 01/31/2028

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer