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Development of SMART on FHIR interoperable clinical decision support for emergency department patients with pneumonia and pilot deployment into novel Epic electronic health record environments

Award Number: R18HS028955
ORGANIZATION: AGENCY FOR HEALTH CARE RESEARCH AND QUALITY
OPDIV: AHRQ
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: KDA (KNOWLEDGE/DEVELOPMENT/APPLICATION)
PERIOD OF PERFORMANCE START DATE: 08/01/2023
PERIOD OF PERFORMANCE END DATE: 07/31/2026

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Development of SMART on FHIR interoperable clinical decision support for emergency department patients with pneumonia and pilot deployment into novel Epic electronic health record environments - Project Summary In the United States, more than 1.5 million adults are hospitalized each year with community-acquired pneumonia. Despite availability of high-quality guidelines for the treatment of patients with pneumonia, guideline adherence remains poor and patient care is variable. Lack of objective risk assessment leads to unnecessary hospital admissions and misallocation of scarce intensive care resources. Thus, there is a critical need for well-designed clinical decision support (CDS) tools to assist clinicians with accurate diagnosis and appropriate treatment for patients with pneumonia. Intermountain Healthcare developed and deployed real-time electronic CDS (called ePNa) embedded in the Cerner electronic health record (EHR) across 20 adult hospital emergency departments. ePNa gathers real- time and historical data from the EHR combined with artificial intelligence processing of chest images (ChexED) to guide pneumonia diagnosis, risk stratification, site of care, risk of antibiotic resistance, and treatment. ePNa smooths transitions of care between clinicians. Our work incorporates the Five Rights of CDS to optimize the technology’s strengths in the clinical environment. Two controlled studies demonstrate that ePNa increases guideline-recommended, best practice care and decreases 30-day all-cause mortality in adults with pneumonia. ePNa is ready to be deployed to additional environments with distinct patient populations and EHRs. However, siloed EHRs limit technology developed within one vendor from being shared with others. The objective of this proposal is to enable broad dissemination of ePNa by optimizing its interoperability, scalability, and usability. Accordingly, we aim to (1) Develop a SMART on FHIR ePNa application capable of interfacing with both the Cerner and Epic EMRs and conduct a formative evaluation through an iterative design process. We will rapidly refine and validate the new ePNa application. (2) Engage patients and clinicians to inform the patient-centeredness of ePNa’s clinical interface. The project will incorporate feedback from stakeholder clinicians, administrators, and patients to understand contextual factors affecting implementation success in a novel geographic and demographic environment. (3) Evaluate the feasibility and acceptability of ePNa through a pilot implementation trial guided by the RE-AIM QuEST framework. Our proposal is likely to facilitate guideline adherent care for patients with pneumonia broadly across different healthcare systems.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $999,999 )
2025	2025	IHC HEALTH SERVICES INC	36 S STATE ST	SALT LAKE CITY	UT	84111	SALT LAKE	USA	Research on Healthcare Costs, Quality and Outcomes	000	3	9/23/2025	NON-COMPETING CONTINUATION	$999,999
														Subtotal = $999,999

Issue Date FY: 2024 ( Subtotal = $1,000,000 )
2024	2024	INTERMOUNTAIN HEALTH CARE, INC.	36 S STATE ST STE 2200	SALT LAKE CITY	UT	84111	SALT LAKE	USA	Research on Healthcare Costs, Quality and Outcomes	001	2	7/25/2024	NON-COMPETING CONTINUATION	$1,000,000
2024	2023	INTERMOUNTAIN HEALTH CARE, INC.	36 S STATE ST STE 2200	SALT LAKE CITY	UT	84111	SALT LAKE	USA	Research on Healthcare Costs, Quality and Outcomes	000	1	7/25/2024	NEW	$0
														Subtotal = $1,000,000

Issue Date FY: 2023 ( Subtotal = $991,062 )
2023	2023	INTERMOUNTAIN HEALTH CARE, INC.	36 S STATE ST STE 1600	SALT LAKE CITY	UT	84111	SALT LAKE	USA	Research on Healthcare Costs, Quality and Outcomes	000	1	7/26/2023	NEW	$991,062
														Subtotal = $991,062

Grand Total All Awards = $2,991,061

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Development of SMART on FHIR interoperable clinical decision support for emergency department patients with pneumonia and pilot deployment into novel Epic electronic health record environments

Award Number: R18HS028955

ORGANIZATION: AGENCY FOR HEALTH CARE RESEARCH AND QUALITY

OPDIV: AHRQ

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: KDA (KNOWLEDGE/DEVELOPMENT/APPLICATION)

PERIOD OF PERFORMANCE START DATE: 08/01/2023

PERIOD OF PERFORMANCE END DATE: 07/31/2026

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