Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

Link between immunometabolism and epigenetics in malaria vector mosquito Anopheles stephensi.

Award Number: R16AI201108
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/03/2026
PERIOD OF PERFORMANCE END DATE: 08/31/2030

Group Awards By:

View Award Description

Link between immunometabolism and epigenetics in malaria vector mosquito Anopheles stephensi. - Project Summary Malaria is a devastating mosquito-borne disease, and mosquito control is an indispensable strategy for reducing malaria transmission. Epigenetics research represents a new frontier in mosquito biology. In immune cells, aerobic glycolysis constitutes a key metabolic shift characterized by increased lactate production. Lactate-mediated histone lactylation has emerged as a crucial epigenetic mechanism in immune regulation in vertebrates. In mosquitoes, infection with malaria parasites leads to elevated lactate levels, suggesting that this immunometabolic change may modulate the epigenetic control of mosquito immunity against the parasites. In this study, we will employ a multi-omics approach to integrate metabolomic, epigenomic (via ATAC-seq and CUT&Tag), and transcriptomic (via RNA-seq) data, aiming to establish a mechanistic link between immunometabolism and epigenetic regulation in anti-plasmodial immunity in the vector mosquito Anopheles stephensi. This project will serve as a robust platform for training graduate and undergraduate students in frontier research using cutting-edge multi-omics approaches.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $146,671 )
2026	2026	NEW MEXICO STATE UNIVERSITY	1050 STEWART ST.	LAS CRUCES	NM	88003	DONA ANA	USA	Allergy and Infectious Diseases Research	000	1	9/3/2026	NEW	$146,671
														Subtotal = $146,671

Grand Total All Awards = $146,671

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Link between immunometabolism and epigenetics in malaria vector mosquito Anopheles stephensi.

Award Number: R16AI201108

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/03/2026

PERIOD OF PERFORMANCE END DATE: 08/31/2030

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer