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Precision Genome Engineering: From Laboratory to Clinic

Award Number: R13TR006439
ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/19/2026
PERIOD OF PERFORMANCE END DATE: 08/18/2027

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Precision Genome Engineering: From Laboratory to Clinic - Abstract Support is requested for a Keystone Symposia conference entitled Precision Genome Engineering: From Laboratory to Clinic, organized by Drs. Erik J. Sontheimer and Leonela Amoasii, with scientific programming input from Keystone Symposia. The meeting will take place January 25–28, 2027 at Keystone Resort in Keystone, CO. The Keystone Symposia conference on Precision Genome Engineering: From Laboratory to Clinic will highlight transformative advances that are reshaping the future of genetic medicine by pushing the boundaries of what is possible with genome editing technologies. As the field evolves from proof-of-concept to therapeutic application, critical questions around efficiency, specificity, safety, delivery, and scalability of gene editing technologies remain. This conference will address these gaps by convening world leaders and emerging innovators to explore next-generation tools, delivery strategies, integrative technologies, and clinical findings that are redefining genome engineering. The program is designed to showcase cutting-edge research while fostering cross- disciplinary dialogue and collaboration. Attendees will engage in sessions covering innovation in editing systems, viral and non-viral delivery approaches, safety and specificity assessments, and the convergence of genome biology with artificial intelligence. These outcomes will be further advanced by the concurrent Keystone Symposia conference on Tissue-Specific Delivery of Genetic Medicines. Keynote addresses and joint sessions will emphasize in vivo applications and translational readiness, providing a comprehensive view of the field’s trajectory. The meeting will bring together genome engineers, molecular biologists, delivery experts, AI scientists, and translational researchers—providing a dynamic platform to exchange ideas, form new collaborations, and stay at the forefront of scientific and technological innovation. What sets this symposium apart from other conferences on CRISPR technologies or nucleic acid therapeutics is its deep focus on the precision and evolution of genome editing itself, ranging from mechanistic insights to therapeutic design, paired with timely discussions on how AI and delivery systems are accelerating discovery. Attendees will leave with an overview of where the field is headed and how to contribute to its next breakthroughs.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $22,350 )
2026	2026	KEYSTONE SYMPOSIA ON MOLECULAR AND CELLULAR BIOLOGY	160 HWY 6 STE 201	SILVERTHORNE	CO	80498	SUMMIT	USA	National Center for Advancing Translational Sciences	000	1	8/18/2026	NEW	$22,350
														Subtotal = $22,350

Grand Total All Awards = $22,350

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Precision Genome Engineering: From Laboratory to Clinic

Award Number: R13TR006439

ORGANIZATION: NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/19/2026

PERIOD OF PERFORMANCE END DATE: 08/18/2027

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