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Brain and Human Body Modeling Conference ? from Fast and Accurate Computational Modeling to Clinical Practice

Award Number: R13MH127866
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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ABSTRACT Brain stimulation therapies are important and effective treatments for people with depression and other mental disorders. The National Institute of Mental Health (NIMH) is supporting studies exploring how to make brain stimulation therapies more personalized and effective while reducing side effects. For all brain stimulation modalities, computational numerical modeling of the electric fields within a patient-specific head model is the leading and most promising way to develop improved spatial targeting methods and quantitatively determine the required stimulation dose. Similarly, neurophysiological signal analyses require extensive numerical computational modeling to identify active cortical domains from limited electrode voltage and magnetometer measurements. The present proposal will facilitate development of fast and accurate brain and human body modeling methods and techniques via a dedicated computational conference on Brain and Human Body Modeling. Aligned with NIMH’s mission, the specific aims of this proposal and the major technical focus of the conference will include the following: (i) Computational modeling of electric and magnetic fields within the brain targeting neurostimulation modalities (TMS, TES, DBS) and associated neurophysiological recordings (EEG, iEEG, MEG); (ii) Integration of modeling techniques into clinical practice. These modeling techniques are aimed to provide better focality, targeting accuracy, and improve the overall efficiency of the brain stimulation methods. They will also support promising combinations and derivatives of the neuromodulation and neurophysiological recordings such as TMS-EEG and TES-EEG. No established computational methods for modeling these combined modalities currently exist. The conference will include related topics that share very similar, sometimes identical, computational methods and tools. We aim to synergistically share these computational tools for maximal benefit and to facilitate interactions across disciplines.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = -$60 )
2024	2022	WORCESTER POLYTECHNIC INSTITUTE	100 INSTITUTE RD	WORCESTER	MA	01609	WORCESTER	USA	Mental Health Research Grants	000	2	2/20/2024	NON-COMPETING CONTINUATION	-$60
														Subtotal = -$60

Issue Date FY: 2022 ( Subtotal = $10,000 )
2022	2022	WORCESTER POLYTECHNIC INSTITUTE	100 INSTITUTE RD	WORCESTER	MA	01609	WORCESTER	USA	Mental Health Research Grants	000	2	8/8/2022	NON-COMPETING CONTINUATION	$10,000
														Subtotal = $10,000

Issue Date FY: 2021 ( Subtotal = $10,000 )
2021	2021	WORCESTER POLYTECHNIC INSTITUTE	100 INSTITUTE RD	WORCESTER	MA	01609	WORCESTER	USA	Mental Health Research Grants	000	1	8/11/2021	NEW	$10,000
														Subtotal = $10,000

Grand Total All Awards = $19,940

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Brain and Human Body Modeling Conference ? from Fast and Accurate Computational Modeling to Clinical Practice

Award Number: R13MH127866

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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