2026 Lymphatics Gordon Research Conference and Seminar - PROJECT SUMMARY The objectives of the 2026 GRC “Lymphatics” are to present state-of-the-art research on the lymphatic vascular system, to fuel scientific exchange across scientific disciplines and expertise, and to spearhead new ideas and collaborations. The meeting will bring together investigators from all backgrounds and from all career stages, converging on lymphatics as one common theme. Specific Aims are (1) To present conceptual advances in research of the lymphatic vascular system and its pathologies; (2) To discuss paradigm shifting findings of lymphatics in different organ systems and their contribution to disease; (3) To integrate knowledge from different disciplines; and (4) To nurture junior investigators and trainees entering the lymphatic research field. Sessions will cover conceptual advances in development and disease of lymphatic vessels from basic aspects to potential clinical applications. The meeting will highlight recent insights into the diversity and organ-specificity of lymphatic endothelium. Novel molecular regulators for lymphatic vasculature during bone development, Schlemm’s canal in the eye and lacteals in the intestine will be discussed. New factors regulating lymphangiogenesis and lymphatic integrity will be introduced. Advances in research on lymphatic malformations, lymphedema and other congenital lymphatic diseases will be discussed. The meeting will also present emerging concepts on the role of lymphatics in atherosclerosis, myocardial infarction, and congestive heart failure. Paradigm shifts in the field will be presented, and crosstalk between lymphatics and immune system discussed. Advances in understanding how lymphatics contribute to disease, including cardiovascular inflammation, cancer, autoimmune and neurodegenerative diseases will be highlighted. A key goal for this meeting is to serve as a platform for growth of lymphatic research, and for helping to promote new scientists entering this research field. Abundant opportunities for the presentation of research by early career investigators will be provided. The GRS on Lymphatics organized by junior investigators will provide opportunities exclusively for junior investigators to present their work and form collaborations. Aside from presentation and poster sessions, a career development session will also be held during GRS to provide guidance to those just getting their start in the lymphatic research field, and to discuss strategies for how to navigate issues impeding lymphatic research or obstacles to participation by incoming lymphatic researchers. A patient session will also be held to allow researchers to hear from those suffering from lymphatic diseases and hear their perspective on the potential promise of translating lymphatic research into new therapies. The sponsoring organization is dedicated to advancing the frontiers of science. In accordance with its mission, this conference will place emphasis on the presentation of unpublished data, high-quality science and rich discussions in many fields, such as cardiovascular disease, cancer, immunology, metabolism and neurobiology. We anticipate that the opportunities provided to young investigators participating in this conference will facilitate their rise as future leaders of the lymphatic research field.
