2025 Developmental Biology Gordon Research Conference and Gordon Research Seminar - PROJECT SUMMARY Funds are requested to provide partial support for the 2025 Gordon Research Conference and Gordon Research Seminar in Developmental Biology to be held from March 29- April 4, 2025, in California, US. This meeting has been held at 2-year intervals for the past four decades and has brought together outstanding early career and established scientists to share recent advances in the field of development and disease mechanisms building an outstanding and most prestigious mid-size scientific meeting. The meeting in 2025 is focused on the emergence of patterns and shapes in development integrating intrinsic cues from self- organization to the influence of extrinsic environmental impact on development. In 2025, 23 invited speakers, chosen based on their creative contributions to the field the field and their ability to promote fruitful discussions, have confirmed their attendance, of which eleven are men, and twelve women: three Black scientists, one Hispanic scientist, and two Asian scientists, representing nine countries. Chairs will select speakers from poster abstracts to further diversify the program. All participants will be given the opportunity to present their work in poster sessions. By providing a unique opportunity for interactions with senior leaders in the field the Gordon Research Conference and Gordon Research Seminar in Developmental Biology, 2025 expects to define both the present state and the future of the field with a focus emergence of patterns and shapes in development. The meeting has several unique features. It is attended by the entire international field working on diverse organisms and cell systems advancing biology at various cellular and developmental levels, and at this time, this community will focus on specific topics and their current state of knowledge. The objective of this meeting is to exchange information, using a comparative approach to advance our understanding in various processes linking developmental biology. Many collaborations have resulted from these meetings: reagents were exchanged, experiments planned and new ways of looking at development and disease mechanisms have evolved. Topics for this year will revolve around the stem cell models, cell fate decisions, gene regulation, mechanics in development, morphogens and metabolic control, evolutionary principles and developmental disorders emanating from loss of principles of development.