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ASPEN 2019 Research Workshop (RW) The Relationship between the Intestinal Barrier and Chronic Disease

Award Number: R13DK120290
ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 03/01/2019
PERIOD OF PERFORMANCE END DATE: 02/28/2020

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ASPEN 2019 Research Workshop (RW) The Relationship between the Intestinal Barrier and Chronic Disease - PROJECT SUMMARY/ABSTRACT The ASPEN Research Workshop (RW) is a highly successful and scientifically respected international conference bringing together basic scientists, nutrition researchers and clinicians. The 2019 RW “The Relationship between the Intestinal Barrier and Chronic Diseases” will focus on the intestinal epithelial barrier and the development and progression of chronic diseases. The intestinal epithelium is involved in the development and progression of chronic inflammatory diseases. A compromised intestinal epithelial barrier is associated with a variety of chronic inflammatory diseases affecting multiple organ systems and involving all life-stages. A healthy intestinal microbiota educates and maintains the host intestinal health and immune system. In situations of dysbiosis, there is altered intestinal epithelial barrier function that is linked to numerous acute and chronic diseases, likely through increased paracellular permeability, thus allowing translocation of antigens and pathogens from the intestinal lumen into the host. As a result, a self-propagating inflammatory cascade is triggered, promoting the development and persistence of disease, such as type 1 and 2 diabetes and obesity, intestinal disorders such as celiac disease and inflammatory bowel disease, and neurologic disorders such as autism, Parkinson’s disease. The 2019 RW will bring together researchers from ASPEN and from the fields of Gastroenterology, Pathobiology, Nutrition, and Neurology. The 2019 RW topic has key relevance to ASPEN researchers and clinicians given the impact of chronic inflammatory disease on public health and healthcare costs. The aims of the 2019 ASPEN RW are: 1) To bring together basic scientists and clinicians from a range of disciplines and levels of training and experience, with a focus on clinically relevant, and cutting-edge research relating to the mechanisms by which the intestinal barrier modulates the risk for chronic inflammatory diseases. 2) To support translational science by fostering communication and collaboration among interdisciplinary researchers and clinicians to bring research from bench to bed-side. 3) To provide opportunities for mentorship of early career researchers/scientists and trainees. 4) To disseminate the 2019 RW activities and information to the broader scientific community. The 2019 RW will achieve these aims, having focused on a rapidly evolving scientific field with broad clinical relevance. Through interdisciplinary collaborations and our success in prior workshops; the 2019 RW has a well-founded precedence of success in knowledge translation, to advance the science of patient care.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2019 ( Subtotal = $10,000 )
2019	2019	AMERICAN SOCIETY FOR PARENTERAL AND ENTERAL NUTRITION	8401 COLESVILLE RD STE 510	SILVER SPRING	MD	20910	MONTGOMERY	USA	Diabetes, Digestive, and Kidney Diseases Extramural Research	000	1	2/7/2019	NEW	$10,000
														Subtotal = $10,000

Grand Total All Awards = $10,000

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ASPEN 2019 Research Workshop (RW) The Relationship between the Intestinal Barrier and Chronic Disease

Award Number: R13DK120290

ORGANIZATION: NATIONAL INSTITUTE OF DIABETES & DIGESTIVE & KIDNEY DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 03/01/2019

PERIOD OF PERFORMANCE END DATE: 02/28/2020

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