2025 Metabolomics and Human Health Gordon Research Conference and Gordon Research Seminar - Abstract We are requesting support for the 2025 Gordon Research Conference (GRC) on Metabolomics and Human Health: The Interaction Between Humans, Lifestyles and the Environment Viewed Through Metabolism, and the affiliated Gordon Research Seminar (GRS): Metabolomics and Human Health. The GRC/GRS will be held entura Beach Marriott, 2055 Harbor Boulevard, Ventura, California, United States. Our proposed conference brings together world-class metabolomics scientists who are advancing data capture technologies and developing software for data preprocessing and multi-omics analysis, with clinicians, epidemiologists, and bench level researchers to February 1-7, 2025, at the V share advances, describe challenges, and discuss possible solutions that support the use of metabolomics in precision medicine, nutrition, exposomics and environmental health , . The proposed speakers and attendees will come with a wide array of skill sets in metabolism microbiome, genetics, technology advancement, software development, and expertise in pharmacology, toxicology, biochemistry, nutrition, public health, exposure sciences, bioinformatics, informatics, health, and medicine. We have designed a conference (in collaboration with the Gordon Research Conference management) that will ensure a venue for vigorous formal and informal discussions. We will maximize opportunities for prominent investigators to interact with junior attendees of the conference, and those new to the field of metabolomics. Qualified researchers from underrepresented groups, including women, minorities, and persons with disabilities will be encouraged to attend for engaged learning experiences, and to contribute their own perspectives to advancing research. We will prioritize funds from the NIH to support the participation of underrepresented groups. Our proposal will promote the development, and continued involvement, of qualified researchers from underrepresented groups in the field of metabolomics. We are very excited about the diverse range of topics that will be covered at our conference, that span technology and software development, a wide range of disease and therapeutic areas, and will include perspectives from genetic, lifestyle and environmental exposures that define an individual’s or system’s metabotype, and their response to intervention. We expect the GRC/GRS on Metabolomics to continue to be a “go to meeting” for the metabolomics community (>150 attendees at the first two meetings), and particularly as a meeting that focuses on in depth interactions among senior and junior investigators.