2024 Cell Death Gordon Research Conference and Gordon Research Seminar - Abstract We intend to request funds to help support the 2024 Gordon Research Conference (GRC) on Cell Death to be held July 28-August 2, 2024 and its associated Gordon Research Seminar (GRS) to be held July 26-27, 2024 at the Jordon Hotel at Sunday River, US . The Cell Death GRC is among the most highly regarded international conferences in the cell death community. Participants will give oral presentations, lead discussions or present their work in poster format. In keeping with the intimate spirit of the Gordon Conference, attendance will be limited, and presentations will feature unpublished work at the leading edge of this field. The overall goal of this conference is to expedite progress in cell death research and to use research findings for the development of new anti-inflammatory and anti-cancer therapies. A secondary goal is to facilitate collaborations among cell death researchers and investigators in complementary basic, translational and clinical fields. The “Power Hour” during the GRC will provide a platform to address challenges trainees at all levels encounter, especially for those who are from under-privileged minority groups. The GRS target audience are students and postdoctoral trainees. The GRS provides trainees with the opportunity to present their work in a more peer-to-peer setting. The GRS will also have a few established faculties from industry and academia who will provide career counseling and advice to the trainees. We believe the GRS will provide the platform to help trainees launch their own independent research career. The aims of this conference are to: 1) gather established experts, junior scientists and researchers new to this field in a setting that supports structured and casual interactions. 2) promote exchange of cutting edge, innovative and unpublished science relevant to the roles of cell death in healthy and pathologic contexts. 3) expedite discoveries that advance mechanistic knowledge on cell death and facilitate clinical opportunities for the treatment and diagnosis of diseases caused by the dysregulation of this process. The major themes of the meeting will focus on: 1) fundamental mechanisms of different cell death modalities, 2) cell death in inflammatory disorders, 3) host-pathogen interactions, 4) the cross-talk between cell death and immunity, 5) Targeting cell death mechanisms in disease, 6) Inflammation and tissue homeostasis. The meeting will facilitate the alignment of recent breakthrough discoveries with the development of new therapies for infections, immunological disorders, and cancers.