Wednesday, April 2, 2025
4/2/2025
Regulation of Barrier Immunity - ABSTRACT Support is requested for a Keystone Symposia conference entitled Regulation of Barrier Immunity, organized by Drs. David Artis, Yasmine Belkaid, Fiona Powrie and Kenya Honda. The conference will be held in Banff, Alberta, Canada from February 18-21, 2024. The barrier surfaces of multicellular organisms are immunologically active, highly innervated and become sites where host genetic and environmental signals are integrated to regulate local and systemic physiology. These tissues are sites of infection and chronic inflammatory diseases, such as atopic dermatitis, asthma, allergy, inflammatory bowel diseases and cancer. However, fundamental gaps in knowledge remain regarding the complex interplay between the structural components of tissues (epithelium, sensory apparatus, stroma or vasculature) and the microbial factors and inflammatory mediators at barrier sites. This Keystone Symposia conference is designed to explore new cross-disciplinary paradigms in barrier immunity through integration of emerging topics in understanding of host-microbe interactions and environmental factors with sensory networks of the epithelia, nervous and immune systems. This conference will showcase how a multidisciplinary and global approach to barrier immunity and will guide development of new therapeutic strategies for the treatment of multiple infectious and inflammatory diseases including asthma, allergy, inflammatory bowel diseases and cancer.
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