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Digital Implementation Support to Achieve Uptake and Integration of Task-Shared Care for Schizophrenia in Primary Care in India

Award Number: R01MH133230
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 05/01/2024
PERIOD OF PERFORMANCE END DATE: 03/31/2029

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Digital Implementation Support to Achieve Uptake and Integration of Task-Shared Care for Schizophrenia in Primary Care in India - Schizophrenia is a major contributor to the burden of disease in the United States and globally. Many individuals living with schizophrenia have limited access to effective psychosocial interventions aimed at promoting recovery, rehabilitation, and community tenure. Further, there is inadequate attention to managing co-occurring chronic medical conditions, contributing to substantially reduced life expectancy. Strong evidence supports community-based schizophrenia care delivered through primary care, combining psychosocial interventions with specialist psychiatric support to improve treatment and recovery outcomes in low-resource settings. However, scalable models for integrating these services into routine care in settings in the United States and globally remain urgently needed. India provides a unique scientific opportunity for this research through its ongoing integration of mental health and non-communicable disease services within primary care, supported by a large frontline health workforce and rapidly expanding digital health infrastructure. Findings from this study will inform development of scalable, community-based models of schizophrenia care directly relevant for the United States, where individuals similarly experience unmet psychosocial needs, high rates of medical comorbidity, and barriers to coordinated care. We will leverage India's digital infrastructure to support task-shared schizophrenia care by training frontline health workers to deliver the evidence-based Community Care for People with Schizophrenia in India (COPSI) psychosocial rehabilitation program while monitoring mental, physical, and functional outcomes over time. We will build on our existing collaboration and robust research infrastructure in rural and urban settings in Madhya Pradesh, India to conduct a hybrid type 1 effectiveness-implementation trial to evaluate whether a digital platform offers added clinical benefit and can support integration of task shared care for schizophrenia into community settings. We will conduct an individual randomized controlled trial enrolling 200 adults with schizophrenia to evaluate whether use of the mindLAMP digital platform can enhance the clinical effectiveness of the COPSI program in reducing disability for individuals living with schizophrenia. We will also measure a range of secondary outcomes for physical health and lifestyle behaviors linked to early mortality, and mental health. We will also determine whether the addition of mindLAMP to the delivery of the COPSI program has an impact on implementation metrics when compared to delivery of COPSI alone. Our study directly supports NIMH priorities by evaluating whether a novel digital platform can enhance the effectiveness and integration of a proven psychosocial rehabilitation intervention for schizophrenia into primary care in India. This study will generate valuable implementation evidence that can directly inform efforts in the United States to improve access to psychosocial rehabilitation and proven services for individuals living with schizophrenia, especially in rural and low-resource settings.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $663,554 )
2026	2026	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Mental Health Research Grants	001	3	7/31/2026	SUPPLEMENT FOR EXPANSION	$272,907
2026	2026	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Mental Health Research Grants	003	3	8/12/2026	SUPPLEMENT FOR EXPANSION	$6,912
2026	2026	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Mental Health Research Grants	000	3	7/22/2026	NON-COMPETING CONTINUATION	$374,879
2026	2026	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Mental Health Research Grants	002	3	8/5/2026	SUPPLEMENT FOR EXPANSION	$8,856
														Subtotal = $663,554

Issue Date FY: 2025 ( Subtotal = $582,399 )
2025	2025	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Mental Health Research Grants	000	2	3/11/2025	NON-COMPETING CONTINUATION	$582,399
														Subtotal = $582,399

Issue Date FY: 2024 ( Subtotal = $817,815 )
2024	2024	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Mental Health Research Grants	000	1	4/12/2024	NEW	$745,671
2024	2024	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	25 SHATTUCK ST	BOSTON	MA	02115	SUFFOLK	USA	Mental Health Research Grants	001	1	4/30/2024	NEW	$72,144
														Subtotal = $817,815

Grand Total All Awards = $2,063,768

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Digital Implementation Support to Achieve Uptake and Integration of Task-Shared Care for Schizophrenia in Primary Care in India

Award Number: R01MH133230

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 05/01/2024

PERIOD OF PERFORMANCE END DATE: 03/31/2029

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