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Social and Biological Mechanisms Driving the Intergenerational Impact of War on Child Mental Health: Implications for Developing Family Based Intervention

Award Number: R01MH128928
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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A. Summary of parent grant There is a widespread recognition that mental health is often neglected, under-resourced, and underfunded, particularly in low- and middle-income countries (LMICs) 1, 2. Experiencing traumatic events as a child is often linked to mental health problems and higher levels of stress reactivity and impact one's entire ecology with long-term intergenerational consequences 3. The treatment gap, is more than 50% in all countries and can be as high as 90% in the least resourced countries 4. Sierra Leone is one of many low and middle-income countries (LMICs) that have encountered challenges in providing mental health services to their population, particularly children and adolescents 5-6. This has been compounded by the country's experiences of war and the Ebola outbreak. The parent grant for the proposed supplement is a mixed-method, longitudinal study evaluating the long-term effects of war and trauma on parents and their relationships with their children, families, and communities. Previous studies have noted the limitations of relying on self-reported family dynamics in post- conflict settings, including Sierra Leone 7. There is a need for observational techniques and instruments that are context-specific, current, biologically based, and tailored to fathers to supplement self-report methods. The findings from this study will inform the development of decision-support tools for lay-worker-delivered prevention models to support family interventions to address specific needs, based on the family's distinct pattern of risk and protective factors. Specific Aims of the parent grant: The primary aims of the parent grant are as follows: (1) Investigate the biological embedding and long-term mental health consequences of war-related trauma in a longitudinal sample of war-affected youth who have become parents (N=394). (2) Examine associations between parental war-related trauma exposure, mental health, and biological and physiological indicators of emotion, cognition, and social functioning in offspring aged 7–24 (N=410). (3) Identify and examine how modifiable risk and protective factors operate to identify priority intervention targets to improve the physical and mental health of war-affected children and to develop screening tools to identify families at risk.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $703,663 )
2024	2024	TRUSTEES OF BOSTON COLLEGE	140 COMMONWEALTH AVE	CHESTNUT HILL	MA	02467	MIDDLESEX	USA	Mental Health Research Grants	000	3	12/14/2023	NON-COMPETING CONTINUATION	$585,944
2024	2024	TRUSTEES OF BOSTON COLLEGE	140 COMMONWEALTH AVE	CHESTNUT HILL	MA	02467	MIDDLESEX	USA	Mental Health Research Grants	001	3	12/19/2023	SUPPLEMENT FOR EXPANSION	$117,719
														Subtotal = $703,663

Issue Date FY: 2023 ( Subtotal = $731,283 )
2023	2023	TRUSTEES OF BOSTON COLLEGE	140 COMMONWEALTH AVE	CHESTNUT HILL	MA	02467	MIDDLESEX	USA	Mental Health Research Grants	001	2	1/20/2023	NON-COMPETING CONTINUATION	$66,733
2023	2023	TRUSTEES OF BOSTON COLLEGE	140 COMMONWEALTH AVE	CHESTNUT HILL	MA	02467	MIDDLESEX	USA	Mental Health Research Grants	002	2	7/7/2023	SUPPLEMENT FOR EXPANSION	$63,946
2023	2023	TRUSTEES OF BOSTON COLLEGE	140 COMMONWEALTH AVE	CHESTNUT HILL	MA	02467	MIDDLESEX	USA	Mental Health Research Grants	000	2	12/19/2022	NON-COMPETING CONTINUATION	$600,604
2023	2023	TRUSTEES OF BOSTON COLLEGE	140 COMMONWEALTH AVE	CHESTNUT HILL	MA	02467	MIDDLESEX	USA	Mental Health Research Grants	003	2	7/19/2023	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $731,283

Issue Date FY: 2022 ( Subtotal = $722,095 )
2022	2022	TRUSTEES OF BOSTON COLLEGE	140 COMMONWEALTH AVE	CHESTNUT HILL	MA	02467	MIDDLESEX	USA	Mental Health Research Grants	000	1	2/10/2022	NEW	$722,095
2022	2022	TRUSTEES OF BOSTON COLLEGE	140 COMMONWEALTH AVE	CHESTNUT HILL	MA	02467	MIDDLESEX	USA	Mental Health Research Grants	001	1	4/5/2022	NEW	$0
														Subtotal = $722,095

Grand Total All Awards = $2,157,041

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Social and Biological Mechanisms Driving the Intergenerational Impact of War on Child Mental Health: Implications for Developing Family Based Intervention

Award Number: R01MH128928

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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