Sunday, November 24, 2024 11/24/2024

Tcher, Take Charge: Increasing PrEP Awareness, Uptake, and Adherence Through Health Care Empowerment and Addressing Social Determinants of Health Among Racially Diverse Trans Women in the Deep South

Award Number: R01MH128049
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Abstract Trans women are highly underserved in the response to HIV, especially in the deep south. Southern states are disproportionately impacted by HIV. Among states in the deep south, which face the vast majority of new HIV infections, HIV diagnosis rates in Louisiana were second only to Georgia. In New Orleans, our team conducted the first population- base HIV surveillance study of trans women and 46% tested positive for HIV. These findings are consistent with the most recent Louisiana Department of Health (LDH) STD/HIV annual report in 2018 that identified Black gay/bisexual men and transgender women as bearing the largest burden of HIV of any population in Louisiana. Despite the impact of HIV on trans women in New Orleans, no evidence-based PrEP interventions or efforts are underway to meet community needs. In response to RFA-MH-21-151 Strengthening HIV Prevention Efforts for Women in the Southern U.S., our team proposes to test the T'Cher, Take Charge intervention to increase PrEP awareness, uptake, and adherence among trans women in New Orleans. T'Cher builds off the work conducted to inform and implement the first population-based study of trans women in 2019 with the adaptation of two evidence-based interventions for trans women recently completed by investigators. The intervention will include a social media campaign to increase PrEP awareness among trans women. It will also include peer navigation to build trust among trans people and provide PrEP navigation. We will tailor the peer navigation model from the Stay Study to be implemented digitally and enhanced using Health eNav methods. Namely, we will also use motivational interviewing and EMAs to increase health care empowerment and address social determinants of health barriers to PrEP uptake and adherence. We will recruit 200 trans women to participate in our study using methods proven successful in our prior HIV research with trans women. Trans women will be engaged in the intervention for 12 months, providing enough time to address barriers to PrEP and support adherence. The goals of this proposed T'Cher, Take Charge intervention are: (1) To develop, implement and measure the impact of a T'Cher, Take Charge social media campaign on PrEP awareness among trans women in New Orleans, LA using a population-based sample of trans women; (2) To test the impact of the T'Cher, Take Charge digital mHealth peer navigation model on increasing PrEP uptake and adherence among trans women in New Orleans, LA, using a randomized stepped wedge cross-over study design; and, (3) To assess changes in health care empowerment and support for social determinants of health as mediating factors in PrEP uptake and adherence. Our goal is to used lessons learned to adapt promising trans-specific HIV interventions to meet the HIV prevention needs of trans women in New Orleans, Louisiana. With evidence of effectiveness, we are prepared to test the intervention at scale throughout Louisiana to strengthen PrEP access and utilization among trans women Louisiana and throughout the deep south.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	000	4	11/21/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $524,200 )
2024	2024	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	004	4	9/6/2024	NON-COMPETING CONTINUATION	$0
2024	2024	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	003	4	8/30/2024	NON-COMPETING CONTINUATION	$524,200
2024	2023	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	000	3	4/16/2024	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2024	2023	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	002	3	7/30/2024	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$353,166
2024	2022	NO AIDS TASK FORCE	1631 ELYSIAN FIELDS AVE	NEW ORLEANS	LA	70117	ORLEANS	USA	Mental Health Research Grants	001	2	7/30/2024	NON-COMPETING CONTINUATION	-$353,166
														Subtotal = $524,200

Issue Date FY: 2023 ( Subtotal = $654,748 )
2023	2023	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	002	3	9/13/2023	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$654,748
2023	2022	NO/AIDS TASK FORCE	1631 ELYSIAN FIELDS AVE	NEW ORLEANS	LA	70117	ORLEANS	USA	Mental Health Research Grants	000	2	8/1/2023	NON-COMPETING CONTINUATION	$0
2023	2022	NO/AIDS TASK FORCE	1631 ELYSIAN FIELDS AVE	NEW ORLEANS	LA	70117	ORLEANS	USA	Mental Health Research Grants	001	2	9/13/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $654,748

Issue Date FY: 2022 ( Subtotal = $643,139 )
2022	2022	NO/AIDS TASK FORCE	1631 ELYSIAN FIELDS AVE	NEW ORLEANS	LA	70117	ORLEANS	USA	Mental Health Research Grants	000	2	9/2/2022	NON-COMPETING CONTINUATION	$643,139
2022	2022	NO/AIDS TASK FORCE	1631 ELYSIAN FIELDS AVE	NEW ORLEANS	LA	70117	ORLEANS	USA	Mental Health Research Grants	001	2	9/8/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $643,139

Issue Date FY: 2021 ( Subtotal = $694,952 )
2021	2021	NO/AIDS TASK FORCE	1631 ELYSIAN FIELDS AVE	NEW ORLEANS	LA	70117	ORLEANS	USA	Mental Health Research Grants	000	1	9/17/2021	NEW	$694,952
														Subtotal = $694,952

Grand Total All Awards = $2,517,039

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Tcher, Take Charge: Increasing PrEP Awareness, Uptake, and Adherence Through Health Care Empowerment and Addressing Social Determinants of Health Among Racially Diverse Trans Women in the Deep South

Award Number: R01MH128049

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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