Wednesday, September 17, 2025 9/17/2025

T’Cher, Take Charge: A Increasing PrEP Awareness, Uptake, and Adherence Through Health Care Empowerment and Addressing Social Drivers of Health in the Deep South

Award Number: R01MH128049
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/17/2021
PERIOD OF PERFORMANCE END DATE: 07/31/2026

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T’Cher, Take Charge: A Increasing PrEP Awareness, Uptake, and Adherence Through Health Care Empowerment and Addressing Social Drivers of Health in the Deep South - New cases of HIV epidemic continue to rise in the Deep South. Among states in the Deep South that report most new HIV infections, HIV diagnosis rates in Louisiana were second only to Georgia. Our team conducted the first population- base HIV surveillance study of key high-risk populations in southeastern Louisiana and 46% tested positive for HIV. These findings are consistent with the most recent Louisiana Department of Health (LDH) STD/HIV annual report in 2018 that identified high risk groups as bearing the largest burden of HIV in Louisiana. Despite the impact of HIV on high-risk groups in New Orleans, no evidence-based PrEP interventions or efforts are underway to meet community needs. Our team proposes to test the T’Cher Take Charge: Increasing PrEP Awareness, Uptake, and Adherence Through Health Care Empowerment and Addressing Social Behavioral Drivers of Health Barriers in the Deep South intervention. The intervention will include a social media campaign to increase PrEP awareness. It will also include peer navigation to build trust and provide PrEP navigation. We will tailor the peer navigation model from a prior study to be implemented digitally and enhanced using mHealth methods. Namely, we will also use motivational interviewing and ecological momentary assessments to increase health care empowerment and address social behavioral drivers that create barriers to PrEP uptake and adherence. We will recruit 200 participants in our study using methods proven successful in our prior HIV research. Participants will be engaged in the intervention for 12 months, providing enough time to address barriers to PrEP and support adherence. The goals of this proposed T'Cher, Take Charge intervention are: (1) To develop, implement and measure the impact of a T'Cher, Take Charge social media campaign on PrEP awareness among participants in LA using a population-based sample; (2) To test the impact of the T'Cher, Take Charge digital mHealth peer navigation model on increasing PrEP uptake and adherence among participants in LA, using a randomized stepped wedge cross-over study design; and, (3) To assess changes in health care empowerment and support for social behavioral drivers as mediating factors in PrEP uptake and adherence. Our goal is to used lessons learned to adapt existing HIV prevention interventions to meet the needs of high-risk groups in Louisiana. With evidence of effectiveness, we are prepared to test the intervention at scale throughout the Deep South to strengthen PrEP access and utilization in the Deep South.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $559,464 )
2025	2025	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	003	5	7/28/2025	NON-COMPETING CONTINUATION	$559,464
2025	2024	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	000	4	11/21/2024	NON-COMPETING CONTINUATION	$0
2025	2024	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	002	4	7/3/2025	NON-COMPETING CONTINUATION	$0
2025	2024	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	001	4	3/20/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $559,464

Issue Date FY: 2024 ( Subtotal = $524,200 )
2024	2024	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	003	4	8/30/2024	NON-COMPETING CONTINUATION	$524,200
2024	2024	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	004	4	9/6/2024	NON-COMPETING CONTINUATION	$0
2024	2023	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	000	3	4/16/2024	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2024	2023	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	002	3	7/30/2024	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$353,166
2024	2022	NO AIDS TASK FORCE	1631 ELYSIAN FIELDS AVE	NEW ORLEANS	LA	70117	ORLEANS	USA	Mental Health Research Grants	001	2	7/30/2024	NON-COMPETING CONTINUATION	-$353,166
														Subtotal = $524,200

Issue Date FY: 2023 ( Subtotal = $654,748 )
2023	2023	PUBLIC HEALTH FOUNDATION ENTERPRISES, INC.	13300 CROSSROADS PKWY N	CITY OF INDUSTRY	CA	91746	LOS ANGELES	USA	Mental Health Research Grants	002	3	9/13/2023	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$654,748
2023	2022	NO/AIDS TASK FORCE	1631 ELYSIAN FIELDS AVE	NEW ORLEANS	LA	70117	ORLEANS	USA	Mental Health Research Grants	001	2	9/13/2023	NON-COMPETING CONTINUATION	$0
2023	2022	NO/AIDS TASK FORCE	1631 ELYSIAN FIELDS AVE	NEW ORLEANS	LA	70117	ORLEANS	USA	Mental Health Research Grants	000	2	8/1/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $654,748

Issue Date FY: 2022 ( Subtotal = $643,139 )
2022	2022	NO/AIDS TASK FORCE	1631 ELYSIAN FIELDS AVE	NEW ORLEANS	LA	70117	ORLEANS	USA	Mental Health Research Grants	001	2	9/8/2022	NON-COMPETING CONTINUATION	$0
2022	2022	NO/AIDS TASK FORCE	1631 ELYSIAN FIELDS AVE	NEW ORLEANS	LA	70117	ORLEANS	USA	Mental Health Research Grants	000	2	9/2/2022	NON-COMPETING CONTINUATION	$643,139
														Subtotal = $643,139

Issue Date FY: 2021 ( Subtotal = $694,952 )
2021	2021	NO/AIDS TASK FORCE	1631 ELYSIAN FIELDS AVE	NEW ORLEANS	LA	70117	ORLEANS	USA	Mental Health Research Grants	000	1	9/17/2021	NEW	$694,952
														Subtotal = $694,952

Grand Total All Awards = $3,076,503

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T’Cher, Take Charge: A Increasing PrEP Awareness, Uptake, and Adherence Through Health Care Empowerment and Addressing Social Drivers of Health in the Deep South

Award Number: R01MH128049

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/17/2021

PERIOD OF PERFORMANCE END DATE: 07/31/2026

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