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HIGH-RISK ESTABLISHMENTS AND WOMEN'S HIV PREVENTION IN SOUTHERN CHINA

Award Number: R01MH077541
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 02/01/2007
PERIOD OF PERFORMANCE END DATE: 01/31/2012

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HIGH-RISK ESTABLISHMENTS AND WOMEN'S HIV PREVENTION IN SOUTHERN CHINA - DESCRIPTION (provided by applicant): This 5-year study, entitled "High-risk Establishments and Women's HIV Prevention in Southern China," is a Phase I/Phase II study of HIV risk and social dynamics in sex-work establishments, and the development and evaluation of a multi-level, site-based intervention conducted within those establishments to promote use of the female condom (FC) for HIV/STD prevention among women who work there. Based on a collaboration developed through an AIDS-FIRCA study, U.S. and Chinese investigators will work with Hainan and Guanxi provincial CDCs and local communities to conduct the study in two rural and two mid-sized urban towns in these provinces. The study aims are: 1) to assess the number and nature of sex-work establishments in these towns, and the stability and social dynamics within these establishments that affect delivery and testing of a site-base intervention to promote FC use for HIV prevention; 2) to assess factors associated with HIV risk and use of female and male condoms for HIV prevention among women who work within these establishments; 3) to develop, pilot, conduct a process evaluation, assess short-term efficacy and potential sustainability of, and manualize a site-based, multi-level (individual, site, community) intervention conducted in these establishments to promote the FC for HIV/STD prevention, and 4) to explore factors likely to explain: a) variation in feasibility, acceptability, and fidelity of intervention delivered in different establishments and different towns, and b) variation in short-term efficacy and sustainability of the intervention among women in different establishments and different towns. In each town we will use intensive ethnography to assess the characteristics and dynamics of sex workers and sex-work establishments, as well as the feasibility, process, and outcomes of the intervention conducted in those establishments. We will conduct cross-sectional surveys of sex workers in all 4 towns at three time points (baseline, 6 and 12 months post-baseline) for comparative analyses to assess town-level, sex-work establishment, and individual-level characteristics associated with HIV risk and prevention and outcomes of the intervention. Qualitative and quantitative data will be triangulated to build the strongest assessment of characteristics that affect risk and intervention outcomes and to provide the most comprehensive analysis of factors that enhance or impede use of the FC and other prevention measures by women in these establishments. Development and testing of the FC intervention has significant public health implications because of its potential for reducing sexual HIV transmission in this high-risk population and in the broader population of their sexual networks.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2011 ( Subtotal = $507,089 )
2011	2011	INSTITUTE FOR COMMUNITY RESEARCH	2 HARTFORD SQUARE W STE 100	HARTFORD	CT	06106	CAPITOL	USA	Mental Health Research Grants	001	5	7/7/2011	NON-COMPETING CONTINUATION	$46,099
2011	2011	INSTITUTE FOR COMMUNITY RESEARCH	2 HARTFORD SQUARE W STE 100	HARTFORD	CT	06106	CAPITOL	USA	Mental Health Research Grants	000	5	12/20/2010	NON-COMPETING CONTINUATION	$460,990
														Subtotal = $507,089

Issue Date FY: 2010 ( Subtotal = $522,882 )
2010	2010	INSTITUTE FOR COMMUNITY RESEARCH	2 HARTFORD SQUARE W STE 100	HARTFORD	CT	06106	CAPITOL	USA	Mental Health Research Grants	000	4	1/22/2010	NON-COMPETING CONTINUATION	$522,882
														Subtotal = $522,882

Issue Date FY: 2009 ( Subtotal = $543,597 )
2009	2009	INSTITUTE FOR COMMUNITY RESEARCH	2 HARTFORD SQUARE W STE 100	HARTFORD	CT	06106	CAPITOL	USA	Mental Health Research Grants	001	3	5/6/2009	NON-COMPETING CONTINUATION	$54,360
2009	2009	INSTITUTE FOR COMMUNITY RESEARCH	2 HARTFORD SQUARE W STE 100	HARTFORD	CT	06106	CAPITOL	USA	Mental Health Research Grants	000	3	1/27/2009	NON-COMPETING CONTINUATION	$489,237
														Subtotal = $543,597

Issue Date FY: 2008 ( Subtotal = $464,406 )
2008	2008	INSTITUTE FOR COMMUNITY RESEARCH	2 HARTFORD SQUARE W STE 100	HARTFORD	CT	06106	CAPITOL	USA	Mental Health Research Grants	000	2	1/23/2008	NON-COMPETING CONTINUATION	$464,406
														Subtotal = $464,406

Issue Date FY: 2007 ( Subtotal = $508,786 )
2007	2007	INSTITUTE FOR COMMUNITY RESEARCH	2 HARTFORD SQUARE W STE 100	HARTFORD	CT	06106	CAPITOL	USA	Mental Health Research Grants	000	1	1/23/2007	NEW	$508,786
														Subtotal = $508,786

Grand Total All Awards = $2,546,760

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HIGH-RISK ESTABLISHMENTS AND WOMEN'S HIV PREVENTION IN SOUTHERN CHINA

Award Number: R01MH077541

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 02/01/2007

PERIOD OF PERFORMANCE END DATE: 01/31/2012

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