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Meta-analysis in human brain mapping

Award Number: R01MH074457
ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/15/2006
PERIOD OF PERFORMANCE END DATE: 01/31/2025

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Meta-analysis in human brain mapping - This is the competing renewal of the R01 (MH074457-14) which sustains the BrainMap Project (www.brainmap.org). BrainMap is a neuroimaging research resource facilitating cognitive neuroscience and disease-biomarker discovery via coordinate-based meta-analysis (CBMA). BrainMap provides its end-user community with: curated 3-D coordinate data and experimental metadata from peer-reviewed publications; extensively validated computational tools for CBMA; CBMA-derived tools for data interpretation (e.g., functional property and disease loadings by location) and data analysis (e.g., via CBMA-derived disease models); instructional materials and on-site and on-line venues for learning CBMA methods; and, on-going end-user support. At present, BrainMap.org hosts two coordinate-based databases: task-activation (TA DB) and voxel- based morphometry (VBM DB). A voxel-based physiology database (VBP DB) is in the planning and piloting phase. BrainMap maintains an integrated pipeline of cross-platform (Java) tools for data coding (Scribe), filtered retrieval (Sleuth), activation-likelihood estimation (ALE) CBMA (GingerALE), data visualization (Mango), and data interpretation (CBMA-derived Mango plugins). Multiple network-modeling approaches have been successfully applied to BrainMap data – independent components analysis (ICA), author-topic modeling (ATM), graph-theory modeling (GTM), structural equation modeling (SEM), connectivity-based parcellation (CBP), and meta-analytic connectivity modeling (MACM) – but none are yet optimized and “pipelined” for general use. Utilization of BrainMap resources is substantial: our software, data and meta-data have been used in >1,000 peer-reviewed articles. Of these, > 500 were published in the current funding cycle (2015- 2020). Four aims are proposed, to maintain and extend this high-impact research resource. Aim 1. Voxel-based Physiology DataBase (VBP DB) with Analysis Exemplars. Aim 2. BrainMap Community Portal for Multivariate Modeling with Applications & Exemplars. Aim 3. Large-scale Parameter Estimations. Aim 4. BrainMap Pipeline Enhancements and Community Support.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $575,925 )
2024	2024	THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	001	17	8/14/2024	NON-COMPETING CONTINUATION	$57,592
2024	2024	THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	000	17	4/25/2024	NON-COMPETING CONTINUATION	$518,333
														Subtotal = $575,925

Issue Date FY: 2023 ( Subtotal = $575,925 )
2023	2023	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	000	16	3/6/2023	NON-COMPETING CONTINUATION	$575,925
														Subtotal = $575,925

Issue Date FY: 2022 ( Subtotal = $557,835 )
2022	2022	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	000	15	1/14/2022	NON-COMPETING CONTINUATION	$502,051
2022	2022	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	001	15	5/10/2022	NON-COMPETING CONTINUATION	$55,784
														Subtotal = $557,835

Issue Date FY: 2021 ( Subtotal = $683,097 )
2021	2021	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	001	14	9/8/2021	COMPETING CONTINUATION	$45,791
2021	2021	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	000	14	3/26/2021	COMPETING CONTINUATION	$637,306
														Subtotal = $683,097

Issue Date FY: 2020 ( Subtotal = -$48,582 )
2020	2018	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	001	13	5/11/2020	NON-COMPETING CONTINUATION	-$48,582
2020	2018	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	000	13	12/9/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = -$48,582

Issue Date FY: 2018 ( Subtotal = $687,236 )
2018	2018	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	000	13	4/20/2018	NON-COMPETING CONTINUATION	$687,236
														Subtotal = $687,236

Issue Date FY: 2017 ( Subtotal = $687,236 )
2017	2017	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	001	12	8/18/2017	NON-COMPETING CONTINUATION	$68,725
2017	2017	UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER OF SAN ANTONIO	7703 FLOYD CURL DR	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	000	12	4/3/2017	NON-COMPETING CONTINUATION	$618,511
														Subtotal = $687,236

Issue Date FY: 2016 ( Subtotal = $668,329 )
2016	2016	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	000	11	4/15/2016	NON-COMPETING CONTINUATION	$630,521
2016	2016	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	001	11	8/30/2016	SUPPLEMENT FOR EXPANSION	$37,808
														Subtotal = $668,329

Issue Date FY: 2015 ( Subtotal = $722,489 )
2015	2015	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	001	10	4/27/2015	COMPETING CONTINUATION	$6,073
2015	2015	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	000	10	3/10/2015	COMPETING CONTINUATION	$716,416
														Subtotal = $722,489

Issue Date FY: 2014 ( Subtotal = $614,757 )
2014	2014	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	000	9	5/23/2014	NON-COMPETING CONTINUATION	$614,757
														Subtotal = $614,757

Issue Date FY: 2013 ( Subtotal = $602,922 )
2013	2013	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	000	8	7/12/2013	NON-COMPETING CONTINUATION	$602,922
														Subtotal = $602,922

Issue Date FY: 2012 ( Subtotal = $640,093 )
2012	2012	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	000	7	5/1/2012	NON-COMPETING CONTINUATION	$640,093
														Subtotal = $640,093

Issue Date FY: 2011 ( Subtotal = $658,731 )
2011	2011	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	000	6	7/14/2011	NON-COMPETING CONTINUATION	$658,731
														Subtotal = $658,731

Issue Date FY: 2010 ( Subtotal = $693,899 )
2010	2010	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	000	5	7/21/2010	COMPETING CONTINUATION	$693,899
2010	2010	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78284	BEXAR	USA	Mental Health Research Grants	001	5	8/27/2010	COMPETING CONTINUATION	$0
														Subtotal = $693,899

Issue Date FY: 2009 ( Subtotal = $601,138 )
2009	2009	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78229	BEXAR	USA	Mental Health Research Grants	001	4	8/25/2009	NON-COMPETING CONTINUATION	$512,706
2009	2009	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78229	BEXAR	USA	Trans-NIH Recovery Act Research Support	000	3	6/2/2009	SUPPLEMENT FOR EXPANSION	$88,432
														Subtotal = $601,138

Issue Date FY: 2008 ( Subtotal = $498,019 )
2008	2008	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78284	BEXAR	USA	Mental Health Research Grants	000	3	7/22/2008	NON-COMPETING CONTINUATION	$498,019
														Subtotal = $498,019

Issue Date FY: 2007 ( Subtotal = $498,203 )
2007	2007	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78284	BEXAR	USA	Mental Health Research Grants	000	2	8/21/2007	NON-COMPETING CONTINUATION	$498,203
														Subtotal = $498,203

Issue Date FY: 2006 ( Subtotal = $564,350 )
2006	2006	UNIVERSITY OF TEXAS HEALTH SCIENCE CTR AT SAN ANTONIO	7703 FLOYD CURL DRIVE	SAN ANTONIO	TX	78284	BEXAR	USA	Mental Health Research Grants	000	1	9/11/2006	NEW	$564,350
														Subtotal = $564,350

Grand Total All Awards = $10,481,602

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Meta-analysis in human brain mapping

Award Number: R01MH074457

ORGANIZATION: NATIONAL INSTITUTE OF MENTAL HEALTH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/15/2006

PERIOD OF PERFORMANCE END DATE: 01/31/2025

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