Wednesday, March 25, 2026 3/25/2026

The ADELANTE Trial: Testing a multi-level approach for improving household food insecurity and glycemic control among Latinos with diabetes

Award Number: R01MD016738
ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/04/2021
PERIOD OF PERFORMANCE END DATE: 04/30/2027
AWARD TERMINATION DATE: 03/29/2025

Group Awards By:

View Award Description

The ADELANTE Trial: Testing a multi-level approach for improving household food insecurity and glycemic control among Latinos with diabetes - PROJECT SUMMARY Hispanic households in the United States disproportionately experience food insecurity (22%). Food insecurity, defined as the lack of access to safe, affordable, and health-promoting foods, presents a challenge for effective management of nutrition-sensitive chronic conditions such as prediabetes and diabetes. This is especially distressing for Hispanic adults with prediabetes and diabetes, given that food insecurity is associated with worse glycemic control. Food is Medicine, the integration of nutrition programs with healthcare, holds promise for addressing the dual challenge of food insecurity and diabetes management. The goal of ADELANTE (Addressing Diabetes by ELevating Access to Nutrition: A Trial of Effectiveness) is to determine whether a Food is Medicine intervention to improve household food insecurity and glycemic control is effective for Hispanic patients with prediabetes or diabetes. We will use a type 1 hybrid trial to assess the effectiveness of the Food is Medicine intervention on the primary outcome of glycemic control (HbA1c) at 6 months. Participants (n=355) will be randomized to either: 1) 12 weeks of household deliveries of fiber-rich foods (vegetables, beans/legumes, and whole grains) plus a 12-month remotely delivered, culturally-adapted lifestyle behavioral intervention called Vida Sana, or 2) a waitlist control arm, receiving the intervention after a 6-month delay. We will follow participants for 12 months to assess the primary outcome of HbA1c at 6 months, as well as key secondary outcomes, such as HbA1c at 12 months and diabetes-related stress at 6 and 12 months. Additionally, we will recruit up to 2 household members for each participant to assess household-level secondary outcomes, such as household food insecurity and dietary behaviors. To assess the future potential of implementation and dissemination of the multilevel intervention in primary care, we will use mixed methods including quantitative measures (e.g., intervention dose and fidelity) and qualitative interviews with participants and key stakeholders (e.g., providers, clinic leadership, and a community-supported agricultural group) according to the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework. We will involve patients and our longstanding community partners in all phases of the trial. The trial will take place in Alameda County, California, which is home to a large Hispanic population, at La Clínica de La Raza, a community clinic with multiple locations throughout Alameda County. Successful completion of these aims will provide evidence of the effectiveness of a Food is Medicine program for improving household food insecurity and glycemic control among Hispanic adults with prediabetes or diabetes and their household members.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2025	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Minority Health and Health Disparities Research	000	5	3/2/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $601,932 )
2025	2025	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Minority Health and Health Disparities Research	001	5	8/4/2025	NON-COMPETING CONTINUATION	$601,932
2025	2024	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Minority Health and Health Disparities Research	000	4	3/28/2025	TERMINATION	$0
														Subtotal = $601,932

Issue Date FY: 2024 ( Subtotal = $729,220 )
2024	2024	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Minority Health and Health Disparities Research	001	4	5/2/2024	SUPPLEMENT FOR EXPANSION	$159,542
2024	2024	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Minority Health and Health Disparities Research	000	4	4/30/2024	NON-COMPETING CONTINUATION	$569,678
														Subtotal = $729,220

Issue Date FY: 2023 ( Subtotal = $711,921 )
2023	2023	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Minority Health and Health Disparities Research	000	3	5/27/2023	NON-COMPETING CONTINUATION	$602,271
2023	2023	THE LELAND STANFORD JUNIOR UNIVERSITY	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Minority Health and Health Disparities Research	001	3	9/11/2023	SUPPLEMENT FOR EXPANSION	$109,650
														Subtotal = $711,921

Issue Date FY: 2022 ( Subtotal = $625,260 )
2022	2022	LELAND STANFORD JUNIOR UNIVERSITY, THE	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Minority Health and Health Disparities Research	001	2	5/12/2022	NON-COMPETING CONTINUATION	$625,260
2022	2021	LELAND STANFORD JUNIOR UNIVERSITY, THE	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Minority Health and Health Disparities Research	000	1	11/10/2021	NEW	$0
														Subtotal = $625,260

Issue Date FY: 2021 ( Subtotal = $669,976 )
2021	2021	LELAND STANFORD JUNIOR UNIVERSITY, THE	450 JANE STANFORD WAY	STANFORD	CA	94305	SANTA CLARA	USA	Minority Health and Health Disparities Research	000	1	8/4/2021	NEW	$669,976
														Subtotal = $669,976

Grand Total All Awards = $3,338,309

Top

All Categories

About

Search

Reports

Data Submission

Award Information

The ADELANTE Trial: Testing a multi-level approach for improving household food insecurity and glycemic control among Latinos with diabetes

Award Number: R01MD016738

ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/04/2021

PERIOD OF PERFORMANCE END DATE: 04/30/2027

AWARD TERMINATION DATE: 03/29/2025

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer