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Using agent-based modeling to compare strategies that can reduce rural-urban disparities in cardiovascular disease

Award Number: R01MD013886
ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/11/2019
PERIOD OF PERFORMANCE END DATE: 02/28/2025

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Using agent-based modeling to compare strategies that can reduce rural-urban disparities in cardiovascular disease - Project Summary Rural-urban disparities in mortality attributable to cardiovascular disease (CVD) have widened in the United States during the past several decades. The complex interplay of preventive health care delivery and community-level behavioral and contextual factors contribute to the differences in cardiovascular health between rural and urban residents. Recently, systems science and simulation modeling have played an important role in the evaluation, selection, and implementation of evidence-based interventions. However, existing models do not account for either the specific characteristics of populations living in rural communities, or the health care services and other contextual factors of these communities. We propose to use agent-based modeling -- a systems science approach that incorporates data from various sources and simulates real-world clinical or community settings -- to help disentangle these complexities, elucidate causal pathways, and identify potentially effective interventions in rural communities. Our long-term goal is to find effective clinical and public health solutions to reduce rural-urban disparities in cardiovascular health among rural communities in Georgia and New York. Taking an integrated preventive health care and community perspective, we will accomplish our specific aims using an agent-based model of community-based CVD prevention and test the effectiveness of the following interventions at the rural county level. First, we will estimate the health impact of improving health care delivery and access using home-based telemonitoring programs and expanding insurance coverage, focusing on three major CVD risk factors: hypertension, diabetes and high cholesterol (Aim 1). Second, we will estimate the health impact of public health interventions, including improving the food environment, community-based health promotion, and increasing tobacco taxes for reducing four important lifestyle factors related with CVD: obesity, unhealthy diet, physical inactivity, and smoking (Aim 2). In Aim 3, we will use the CVD Policy Model, a well- validated US population-based CVD epidemiology simulation model and translate projected beneficial effects on the seven risk factors and lifestyles tested in Aim 1 and 2 into downstream impact on CVD events. This will allow us to assess the potential of these individual or combined interventions on rural-urban disparities in the incidence and mortality of CVD and direct medical costs at the state level. The proposed research is innovative because we develop a policy simulation model to inform decision-making for health care and public health management of CVD in rural counties, integrating clinical with community systems to find the most effective evidence-based intervention.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = -$14 )
2025	2022	NEW YORK UNIVERSITY	101 MINEOLA BLVD	MINEOLA	NY	11501	NASSAU	USA	Minority Health and Health Disparities Research	000	5	7/7/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	-$14
														Subtotal = -$14

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2022	NEW YORK UNIVERSITY	101 MINEOLA BLVD	MINEOLA	NY	11501	NASSAU	USA	Minority Health and Health Disparities Research	001	5	2/7/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2022	NEW YORK UNIVERSITY	101 MINEOLA BLVD	MINEOLA	NY	11501	NASSAU	USA	Minority Health and Health Disparities Research	002	5	2/7/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2022	NEW YORK UNIVERSITY	101 MINEOLA BLVD	MINEOLA	NY	11501	NASSAU	USA	Minority Health and Health Disparities Research	000	5	2/7/2024	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $843,333 )
2022	2022	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.	310 EAST CAMPUS RD TUCKER HALL ROOM 409	ATHENS	GA	30602	CLARKE	USA	Minority Health and Health Disparities Research	001	4	4/27/2022	NON-COMPETING CONTINUATION	$38,431
2022	2022	NEW YORK UNIVERSITY	101 MINEOLA BLVD	MINEOLA	NY	11501	NASSAU	USA	Minority Health and Health Disparities Research	009	5	8/2/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	-$1
2022	2022	NEW YORK UNIVERSITY	101 MINEOLA BLVD	MINEOLA	NY	11501	NASSAU	USA	Minority Health and Health Disparities Research	008	5	7/20/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$426,273
2022	2022	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.	310 EAST CAMPUS RD TUCKER HALL ROOM 409	ATHENS	GA	30602	CLARKE	USA	Minority Health and Health Disparities Research	007	4	7/20/2022	NON-COMPETING CONTINUATION	-$1
2022	2022	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.	310 EAST CAMPUS RD TUCKER HALL ROOM 409	ATHENS	GA	30602	CLARKE	USA	Minority Health and Health Disparities Research	000	4	2/7/2022	NON-COMPETING CONTINUATION	$345,875
2022	2022	NEW YORK UNIVERSITY	101 MINEOLA BLVD	MINEOLA	NY	11501	NASSAU	USA	Minority Health and Health Disparities Research	010	5	8/2/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$1
2022	2022	NEW YORK UNIVERSITY	101 MINEOLA BLVD	MINEOLA	NY	11501	NASSAU	USA	Minority Health and Health Disparities Research	011	5	9/6/2022	SUPPLEMENT FOR EXPANSION	$146,720
2022	2022	NEW YORK UNIVERSITY	101 MINEOLA BLVD	MINEOLA	NY	11501	NASSAU	USA	Minority Health and Health Disparities Research	003	5	5/18/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$332,237
2022	2022	NEW YORK UNIVERSITY	101 MINEOLA BLVD	MINEOLA	NY	11501	NASSAU	USA	Minority Health and Health Disparities Research	004	5	6/12/2022	SUPPLEMENT FOR EXPANSION	$364,375
2022	2022	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.	310 EAST CAMPUS RD TUCKER HALL ROOM 409	ATHENS	GA	30602	CLARKE	USA	Minority Health and Health Disparities Research	002	4	5/18/2022	NON-COMPETING CONTINUATION	-$384,305
2022	2021	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.	310 EAST CAMPUS RD TUCKER HALL ROOM 409	ATHENS	GA	30602	CLARKE	USA	Minority Health and Health Disparities Research	005	3	7/20/2022	NON-COMPETING CONTINUATION	-$384,237
2022	2020	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.	310 EAST CAMPUS RD TUCKER HALL ROOM 409	ATHENS	GA	30602	CLARKE	USA	Minority Health and Health Disparities Research	006	2	7/20/2022	SUPPLEMENT FOR EXPANSION	-$42,035
														Subtotal = $843,333

Issue Date FY: 2021 ( Subtotal = $384,237 )
2021	2021	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.	310 EAST CAMPUS RD TUCKER HALL ROOM 409	ATHENS	GA	30602	CLARKE	USA	Minority Health and Health Disparities Research	000	3	2/3/2021	NON-COMPETING CONTINUATION	$345,813
2021	2021	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.	310 EAST CAMPUS RD TUCKER HALL ROOM 409	ATHENS	GA	30602	CLARKE	USA	Minority Health and Health Disparities Research	001	3	3/12/2021	NON-COMPETING CONTINUATION	$38,424
														Subtotal = $384,237

Issue Date FY: 2020 ( Subtotal = $768,104 )
2020	2020	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.	310 EAST CAMPUS RD TUCKER HALL ROOM 409	ATHENS	GA	30602	CLARKE	USA	Minority Health and Health Disparities Research	001	2	1/30/2020	NON-COMPETING CONTINUATION	$384,088
2020	2020	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.	310 EAST CAMPUS RD TUCKER HALL ROOM 409	ATHENS	GA	30602	CLARKE	USA	Minority Health and Health Disparities Research	002	2	6/29/2020	SUPPLEMENT FOR EXPANSION	$384,016
2020	2019	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.	310 EAST CAMPUS RD TUCKER HALL ROOM 409	ATHENS	GA	30602	CLARKE	USA	Minority Health and Health Disparities Research	000	1	1/8/2020	NEW	$0
														Subtotal = $768,104

Issue Date FY: 2019 ( Subtotal = $421,443 )
2019	2019	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.	310 EAST CAMPUS RD TUCKER HALL ROOM 409	ATHENS	GA	30602	CLARKE	USA	Minority Health and Health Disparities Research	000	1	7/11/2019	NEW	$421,443
2019	2019	UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.	310 EAST CAMPUS RD TUCKER HALL ROOM 409	ATHENS	GA	30602	CLARKE	USA	Minority Health and Health Disparities Research	001	1	7/12/2019	NEW	$0
														Subtotal = $421,443

Grand Total All Awards = $2,417,103

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Using agent-based modeling to compare strategies that can reduce rural-urban disparities in cardiovascular disease

Award Number: R01MD013886

ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/11/2019

PERIOD OF PERFORMANCE END DATE: 02/28/2025

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