Thursday, January 1, 2026 1/1/2026

Assessing and improving the resilience of bioinformatics pipelines to data errors

Award Number: R01LM014698
ORGANIZATION: NATIONAL LIBRARY OF MEDICINE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 01/01/2025
PERIOD OF PERFORMANCE END DATE: 12/31/2028

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Assessing and improving the resilience of bioinformatics pipelines to data errors - Project summary Despite significant investments in data curation, errors and other analytical artifacts abound in public biological databases. Such errors can have an important impact on bioinformatics software, leading to analytical errors. In certain applications, such as diagnostics or other clinical settings, such analytical errors can have important consequences. The speed of data generation has far outpaced the speed with which biologists can experimentally characterize molecules and organisms, or curate computer-generated annotations. Simply put, errors cannot be eliminated in a practically-meaningful way. Furthermore, the problems induced by low data quality are not always apparent and, thus, can be overlooked by practitioners, even if they are experts in their own field. This project aims to develop a better understanding of how data interact with the algorithms used in bioinformatics research to create the potential for the analytical errors. This understanding will also lead to the development of algorithms and strategies that are able to protect analytical results from errors in the reference data or in the input provided to the analysis.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $561,850 )
2026	2026	UNIVERSITY OF MARYLAND, COLLEGE PARK	3112 LEE BUILDING	COLLEGE PARK	MD	20742	PRINCE GEORGES	USA	Medical Library Assistance	000	2	12/8/2025	NON-COMPETING CONTINUATION	$561,850
														Subtotal = $561,850

Issue Date FY: 2025 ( Subtotal = $608,586 )
2025	2025	UNIVERSITY OF MARYLAND, COLLEGE PARK	3112 LEE BUILDING	COLLEGE PARK	MD	20742	PRINCE GEORGES	USA	Medical Library Assistance	000	1	12/31/2024	NEW	$608,586
														Subtotal = $608,586

Grand Total All Awards = $1,170,436

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Assessing and improving the resilience of bioinformatics pipelines to data errors

Award Number: R01LM014698

ORGANIZATION: NATIONAL LIBRARY OF MEDICINE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 01/01/2025

PERIOD OF PERFORMANCE END DATE: 12/31/2028

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