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Cueing COVID-19: NLM Administrative Supplement for Research on Coronavirus Disease 2019

Award Number: R01LM012300
ORGANIZATION: NATIONAL LIBRARY OF MEDICINE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/10/2020
PERIOD OF PERFORMANCE END DATE: 07/09/2021

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Cueing COVID-19: NLM Administrative Supplement for Research on Coronavirus Disease 2019 - PROJECT SUMMARY The variability and the complexity of the data needed for clinical care requires clinicians to accurately and efficiently recognize COVID-19 amongst individuals, ranging from asymptomatic infection to multiorgan and systemic manifestations. COVID-19, like sepsis, involves different disease etiologies that span a wide range of syndromes (e.g., initial, inflammatory, hyperinflammatory response). Because patients can present with mild, moderate, or severe symptoms, clinicians must both identify the disease stage and optimal treatment. The factors that trigger severe illness in COVID-19 patients are not completely understood. Like other complex, challenging diagnoses, clinicians in the trenches struggle to diagnose and treat patients using data available in the electronic health record (EHR). In our current NIH NLM R01 “Signaling Sepsis: Developing a Framework to Optimize Alert Design”, we created sepsis specific enhanced visual display models that outranked preference and performance when compared with the usual care of fragmented, non-directed information gathering. For this supplement, we propose the design and development of COVID-19 diagnosis and clinical management enhanced visual display models to support clinicians’ recognition of critical phases in COVID-19 diagnosis and treatment decisions. In order to create the models, we will identify relevant diagnostic and treatment data elements that will include clinical characteristics, laboratory results, and radiology results (e.g., chest CT). Our project will survey emerging models of COVID-19 and its stages, and ensure our models are congruent with best practices that emerge as our knowledge as a medical community evolves. The models provide an EHR based method to mine clinical data to identify the presence of COVID-19 which supports the variety of ways in which COVID-19 presents, availability of data elements, accuracy of diagnostic tests, and the highly infective nature of the disease. Specific Aim 1: To identify emerging patient-specific clinical features of COVID-19 and testing analytics to present critical information for COVID-19 diagnosis and clinical management. Elements include the characteristics listed above (e.g., symptoms, co-morbidities) plus COVID-19 specific test results, including data specific to the tests’ positive and negative predictive values. Specific Aim 2: To develop an EHR embedded CDS tool using our COVID-19 enhanced visual display models using synthesized information obtained through the NLM parent grant and Specific Aim 1. Evaluate the technical feasibility and usability of the novel COVID-19 CDS tool. Why It Matters: During a pandemic, there’s no room for ambiguity as clinicians are required to comb through the EHR. The ability to better visualize and interpret EHR data supports optimal diagnosis and clinical management. Our enhanced visual display models will support clinicians as they evaluate demographic factors, underlying conditions, and comorbidities that identify patients at higher risk of morbidity and mortality and will therefore drive better clinical management.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2022 ( Subtotal = -$20,902 )
2022	2020	MEDSTAR HEALTH RESEARCH INSTITUTE INC	6525 BELCREST RD	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Medical Library Assistance	001	4	12/13/2021	SUPPLEMENT FOR EXPANSION	$0
2022	2019	MEDSTAR HEALTH RESEARCH INSTITUTE INC	6525 BELCREST RD	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Medical Library Assistance	000	4	12/13/2021	NON-COMPETING CONTINUATION	-$20,902
														Subtotal = -$20,902

Issue Date FY: 2020 ( Subtotal = $75,000 )
2020	2020	MEDSTAR HEALTH RESEARCH INSTITUTE, INC.	6525 BELCREST RD STE 700	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Medical Library Assistance	001	4	7/9/2020	SUPPLEMENT FOR EXPANSION	$75,000
2020	2019	MEDSTAR HEALTH RESEARCH INSTITUTE, INC.	6525 BELCREST RD STE 700	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Medical Library Assistance	000	4	7/8/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $75,000

Issue Date FY: 2019 ( Subtotal = $328,896 )
2019	2019	MEDSTAR HEALTH RESEARCH INSTITUTE, INC.	6525 BELCREST RD STE 700	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Medical Library Assistance	002	4	7/11/2019	NON-COMPETING CONTINUATION	$328,896
2019	2017	MEDSTAR HEALTH RESEARCH INSTITUTE, INC.	6525 BELCREST RD STE 700	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Medical Library Assistance	001	2	1/16/2019	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$20,821
2019	2016	CHRISTIANA CARE HEALTH SERVICES, INC.	501 W 14TH ST	WILMINGTON	DE	19801	NEW CASTLE	USA	Medical Library Assistance	000	1	1/16/2019	NEW	-$20,821
														Subtotal = $328,896

Issue Date FY: 2018 ( Subtotal = $343,885 )
2018	2018	MEDSTAR HEALTH RESEARCH INSTITUTE, INC.	6525 BELCREST RD STE 700	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Medical Library Assistance	002	3	7/11/2018	NON-COMPETING CONTINUATION	$343,885
2018	2017	MEDSTAR HEALTH RESEARCH INSTITUTE, INC.	6525 BELCREST RD STE 700	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Medical Library Assistance	001	2	11/1/2017	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$166,064
2018	2016	CHRISTIANA CARE HEALTH SERVICES, INC.	501 W 14TH ST	WILMINGTON	DE	19801	NEW CASTLE	USA	Medical Library Assistance	000	1	11/1/2017	NEW	-$166,064
														Subtotal = $343,885

Issue Date FY: 2017 ( Subtotal = $352,829 )
2017	2017	MED STAR HEALTH RESEARCH INSTITUTE	6525 BELCREST RD STE 700	HYATTSVILLE	MD	20782	PRINCE GEORGES	USA	Medical Library Assistance	001	2	8/31/2017	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$352,829
2017	2016	CHRISTIANA CARE HEALTH SERVICES, INC.	501 W 14TH ST	WILMINGTON	DE	19801	NEW CASTLE	USA	Medical Library Assistance	000	1	8/30/2017	NEW	$0
														Subtotal = $352,829

Issue Date FY: 2016 ( Subtotal = $348,630 )
2016	2016	WILMINGTON MEDICAL CENTER	501 WEST 14TH STREET	WILMINGTON	DE	19899	NEW CASTLE	USA	Medical Library Assistance	000	1	9/5/2016	NEW	$348,630
														Subtotal = $348,630

Grand Total All Awards = $1,428,338

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Cueing COVID-19: NLM Administrative Supplement for Research on Coronavirus Disease 2019

Award Number: R01LM012300

ORGANIZATION: NATIONAL LIBRARY OF MEDICINE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/10/2020

PERIOD OF PERFORMANCE END DATE: 07/09/2021

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