Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

Automated Surveillance of Postoperative Infections (ASPIN)

Award Number: R01HS027417
ORGANIZATION: AGENCY FOR HEALTH CARE RESEARCH AND QUALITY
OPDIV: AHRQ
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/30/2020
PERIOD OF PERFORMANCE END DATE: 07/31/2025

Group Awards By:

View Award Description

Automated Surveillance of Postoperative Infections (ASPIN) - PROJECT SUMMARY/ABSTRACT Our long term goal is to reduce postoperative infections. We will start by developing a system to accurately and completely identify their occurrence by applying machine learning algorithms to electronic health record (EHR) data. We will utilize a comprehensive audit and feedback system to create reports of risk-adjusted rates and specific details of postoperative infectious complications that are shared with surgeons and other healthcare providers to facilitate their awareness. We call this system the Automated Surveillance of Postoperative Infections (ASPIN). ASPIN will be piloted in the four major hospitals of the University of Colorado Health system (UCHealth) with a combined surgical volume of approximately 80,000 patients per year. We expect this will supersede the costly and laborious manual partial sampling of postoperative infectious complications which is current utilized by many hospitals. Specific Aim 1. Expand and enhance models for preoperative risk prediction and postoperative identification of surgical infections using EHR and ACS NSQIP data from patients who underwent operations at four UCHealth hospitals. Specific Aim 1a) Enhance previously-developed models for identification of postoperative infections by controlling Type-I errors via “knockoffs,” a recent statistical innovation for high dimensional model selection using false discovery rate correction. Specific Aim 1b) Deploy natural language processing methods using EHR text reports of these patients to identify additional indicators of postoperative infections and further refine the models. Specific Aim 1c) Create preoperative risk models for infection using EHR data - similar to the models implemented in the AHRQ-funded Surgical Risk Preoperative Assessment System - but that do not require additional data entry by the health care providers. Specific Aim 2. From the beginning of the study, develop ASPIN with input from an Advisory Committee composed of administrators and surgeons from all four UCHealth hospitals. Additional feedback from surgeons will be obtained through focus groups and semi-structured interviews at several steps of ASPIN development and implementation planning. Specific Aim 3. A pilot implementation of ASPIN will utilize the RE-AIM framework to guide and examine the preliminary effectiveness and feasibility of ASPIN at UCHealth. We will recruit 30 surgeon participants from all four UCHealth hospitals to use ASPIN, and we will evaluate the reach, effectiveness, adoption, and implementation of ASPIN. This research responds to AHRQ priorities by utilizing existing data to develop a learning health system with a distinct focus on improving surveillance and reporting of postoperative healthcare-associated infections.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $399,793 )
2024	2024	THE REGENTS OF THE UNIVERSITY OF COLORADO	13001 E 17TH PL STE F428	AURORA	CO	80045	ADAMS	USA	Research on Healthcare Costs, Quality and Outcomes	000	5	6/21/2024	NON-COMPETING CONTINUATION	$399,793
														Subtotal = $399,793

Issue Date FY: 2023 ( Subtotal = $397,060 )
2023	2023	REGENTS OF THE UNIVERSITY OF COLORADO, THE	13001 E 17TH PLACE F428	AURORA	CO	80045	ADAMS	USA	Research on Healthcare Costs, Quality and Outcomes	000	4	7/13/2023	NON-COMPETING CONTINUATION	$397,060
														Subtotal = $397,060

Issue Date FY: 2022 ( Subtotal = $400,000 )
2022	2022	REGENTS OF THE UNIVERSITY OF COLORADO, THE	13001 E 17TH PLACE F428	AURORA	CO	80045	ADAMS	USA	Research on Healthcare Costs, Quality and Outcomes	000	3	7/14/2022	NON-COMPETING CONTINUATION	$400,000
														Subtotal = $400,000

Issue Date FY: 2021 ( Subtotal = $395,050 )
2021	2021	REGENTS OF THE UNIVERSITY OF COLORADO, THE	13001 E 17TH PLACE F428	AURORA	CO	80045	ADAMS	USA	Research on Healthcare Costs, Quality and Outcomes	000	2	7/9/2021	NON-COMPETING CONTINUATION	$395,050
														Subtotal = $395,050

Issue Date FY: 2020 ( Subtotal = $392,599 )
2020	2020	REGENTS OF THE UNIVERSITY OF COLORADO, THE	13001 E 17TH PLACE F428	AURORA	CO	80045	ADAMS	USA	Research on Healthcare Costs, Quality and Outcomes	000	1	9/4/2020	NEW	$392,599
														Subtotal = $392,599

Grand Total All Awards = $1,984,502

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Automated Surveillance of Postoperative Infections (ASPIN)

Award Number: R01HS027417

ORGANIZATION: AGENCY FOR HEALTH CARE RESEARCH AND QUALITY

OPDIV: AHRQ

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/30/2020

PERIOD OF PERFORMANCE END DATE: 07/31/2025

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer