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Daily personal light exposure patterns and sleep in emergency department healthcare workers (administrative supplement to R01 HL146911)

Award Number: R01HL146911
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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PROJECT SUMMARY / ABSTRACT Light is the strongest biological signal influencing the human circadian system, and by extension, sleep. Exposure to light of sufficiently high levels during the daytime, combined with dim light/darkness during the evening and night, is necessary to maintain robust and appropriately timed circadian rhythms in physiology and neuroendocrine secretion, and to promote good sleep of sufficient duration. Conversely, reduced light exposure levels throughout the daytime and increased light exposure occurring at the “wrong time” (e.g., the biological night) can disturb sleep by causing circadian misalignment, disrupting melatonin secretion, increasing neurocognitive arousal, delaying sleep initiation, and worsening sleep quality. The light environment and its impact on sleep is important to consider because sleep influences nearly all aspects of physical and mental health and disease, as well as daily function and performance. Thus, personal light exposure represents an important malleable contextual factor that influences a critical health behavior (sleep). In an ongoing prospective 3-year observational cohort study (R01HL146911, MPI: Chang/Shechter; “IMPROVE Study”), we are evaluating the impact of environmental stressors and disturbed sleep on cardiovascular and psychological risk in emergency department (ED) healthcare workers (HCWs). An overarching goal of the IMPROVE Study is to evaluate the short- and long-term contribution of objectively- estimated short sleep duration and poor quality sleep to acute and progressive changes in blood pressure and psychological risk (e.g., burnout). In the current administrative supplement, we will leverage the infrastructure of the ongoing IMPROVE Study to add on an objective assessment of personal light exposure patterns via a small wearable mini-spectrophotometer (light pin) in a subset of participants who are enrolled in the parent IMPROVE study. This subset of participants will wear the light pin during one of their scheduled annual 2- week data bursts in which sleep is continuously tracked under free-living conditions. The aim of the administrative supplement is to determine the relationship between light exposure patterns and our main behavioral predictor of cardiovascular and psychological risk—sleep. Examining how personal light exposure patterns relate to sleep will provide information on the mechanistic role of this factor in influencing sleep. This work can inform the development of novel behavioral interventions focusing on personal light exposure patterns to improve sleep and downstream health-related outcomes.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $678,304 )
2024	2024	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cardiovascular Diseases Research	000	5	1/16/2024	NON-COMPETING CONTINUATION	$678,304
2024	2022	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cardiovascular Diseases Research	001	3	1/20/2024	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $678,304

Issue Date FY: 2023 ( Subtotal = $767,462 )
2023	2023	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cardiovascular Diseases Research	003	4	3/8/2023	NON-COMPETING CONTINUATION	$76,746
2023	2023	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cardiovascular Diseases Research	001	4	12/30/2022	NON-COMPETING CONTINUATION	$690,716
2023	2022	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cardiovascular Diseases Research	000	3	11/10/2022	SUPPLEMENT FOR EXPANSION	$0
2023	2022	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cardiovascular Diseases Research	002	3	2/1/2023	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $767,462

Issue Date FY: 2022 ( Subtotal = $1,238,606 )
2022	2022	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cardiovascular Diseases Research	001	3	6/8/2022	NON-COMPETING CONTINUATION	$78,203
2022	2022	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cardiovascular Diseases Research	002	3	9/7/2022	SUPPLEMENT FOR EXPANSION	$456,588
2022	2022	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cardiovascular Diseases Research	000	3	1/6/2022	NON-COMPETING CONTINUATION	$703,815
														Subtotal = $1,238,606

Issue Date FY: 2021 ( Subtotal = $794,906 )
2021	2021	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cardiovascular Diseases Research	001	2	5/24/2021	NON-COMPETING CONTINUATION	$79,488
2021	2021	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cardiovascular Diseases Research	000	2	12/17/2020	NON-COMPETING CONTINUATION	$715,418
														Subtotal = $794,906

Issue Date FY: 2020 ( Subtotal = $809,989 )
2020	2020	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK	630 W 168TH ST FL 4	NEW YORK	NY	10032	NEW YORK	USA	Cardiovascular Diseases Research	000	1	12/19/2019	NEW	$809,989
														Subtotal = $809,989

Grand Total All Awards = $4,289,267

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Daily personal light exposure patterns and sleep in emergency department healthcare workers (administrative supplement to R01 HL146911)

Award Number: R01HL146911

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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