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PHORA: A Clinical Decision Support Tool for Patients with Pulmonary Arterial Hypertension

Award Number: R01HL134673
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 04/01/2017
PERIOD OF PERFORMANCE END DATE: 01/31/2023

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PHORA: A Clinical Decision Support Tool for Patients with Pulmonary Arterial Hypertension - ABSTRACT This application seeks to develop a multi-platform clinical decision support system (CDSS) in pulmonary arterial hypertension (PAH) for physicians, PHORA (Pulmonary Hypertension Outcomes Risk Assessment), which can be used to: (a) guide therapeutic decisions and (b) optimize clinical trial design. We will achieve this goal by utilizing clinical trial data from several large databases of completed trials in PAH, an ongoing PAH registry (REVEAL), as well as observational sessions with physicians. The proposed aims co- create the CDSS with a multi-disciplinary group of specialties including: biomedical engineering, advanced PAH physicians, computer science (machine learning/data mining), human computer interaction, and allied health care experts. Our intention is to engage all stakeholders to achieve consensus and thereby assure the acceptance of PHORA into practice. Successful completion of this project will lay the foundation for a prospective, multi-center trial in which PHORA will be evaluated with respect to long-term patient outcomes. The ultimate aim is to disseminate this resource so as to improve the efficiency, efficacy, and cost- effectiveness of this treatment for PAH.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = -$220,211 )
2024	2020	OHIO STATE UNIVERSITY, THE	1960 KENNY RD	COLUMBUS	OH	43210	FRANKLIN	USA	Lung Diseases Research	000	5	12/1/2023	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	-$220,211
														Subtotal = -$220,211

Issue Date FY: 2022 ( Subtotal = $0 )
2022	2020	OHIO STATE UNIVERSITY, THE	1960 KENNY RD	COLUMBUS	OH	43210	FRANKLIN	USA	Lung Diseases Research	000	5	6/24/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
														Subtotal = $0

Issue Date FY: 2021 ( Subtotal = $0 )
2021	2020	ALLEGHENY-SINGER RESEARCH INSTITUTE	320 E NORTH AVE	PITTSBURGH	PA	15212	ALLEGHENY	USA	Lung Diseases Research	000	4	11/30/2020	NON-COMPETING CONTINUATION	-$656,378
2021	2020	OHIO STATE UNIVERSITY, THE	1960 KENNY RD	COLUMBUS	OH	43210	FRANKLIN	USA	Lung Diseases Research	003	5	6/21/2021	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$347,639
2021	2020	OHIO STATE UNIVERSITY, THE	1960 KENNY RD	COLUMBUS	OH	43210	FRANKLIN	USA	Lung Diseases Research	001	5	12/1/2020	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$656,378
2021	2019	ALLEGHENY-SINGER RESEARCH INSTITUTE	320 E NORTH AVE	PITTSBURGH	PA	15212	ALLEGHENY	USA	Lung Diseases Research	002	3	6/21/2021	NON-COMPETING CONTINUATION	-$347,639
														Subtotal = $0

Issue Date FY: 2020 ( Subtotal = $656,378 )
2020	2020	ALLEGHENY-SINGER RESEARCH INSTITUTE	320 E NORTH AVE	PITTSBURGH	PA	15212	ALLEGHENY	USA	Lung Diseases Research	000	4	2/1/2020	NON-COMPETING CONTINUATION	$656,378
														Subtotal = $656,378

Issue Date FY: 2019 ( Subtotal = $656,406 )
2019	2019	ALLEGHENY-SINGER RESEARCH INSTITUTE	320 E NORTH AVE	PITTSBURGH	PA	15212	ALLEGHENY	USA	Lung Diseases Research	000	3	2/1/2019	NON-COMPETING CONTINUATION	$656,406
														Subtotal = $656,406

Issue Date FY: 2018 ( Subtotal = $694,555 )
2018	2018	ALLEGHENY-SINGER RESEARCH INSTITUTE	320 E NORTH AVE	PITTSBURGH	PA	15212	ALLEGHENY	USA	Lung Diseases Research	001	2	6/9/2018	NON-COMPETING CONTINUATION	$13,891
2018	2018	ALLEGHENY-SINGER RESEARCH INSTITUTE	320 E NORTH AVE	PITTSBURGH	PA	15212	ALLEGHENY	USA	Lung Diseases Research	000	2	1/23/2018	NON-COMPETING CONTINUATION	$680,664
														Subtotal = $694,555

Issue Date FY: 2017 ( Subtotal = $749,226 )
2017	2017	ALLEGHENY-SINGER RESEARCH INSTITUTE	320 E NORTH AVE	PITTSBURGH	PA	15212	ALLEGHENY	USA	Lung Diseases Research	000	1	4/1/2017	NEW	$749,226
														Subtotal = $749,226

Grand Total All Awards = $2,536,354

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PHORA: A Clinical Decision Support Tool for Patients with Pulmonary Arterial Hypertension

Award Number: R01HL134673

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 04/01/2017

PERIOD OF PERFORMANCE END DATE: 01/31/2023

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