Tuesday, April 29, 2025
4/29/2025
Measurement of Quality of Life and Perceived Disease Impact on Quality of Life in - DESCRIPTION (provided by applicant): Existing asthma-related quality of life (QoL) scales do not directly assess QoL or the perceived impact of asth- ma on QoL. The purpose of this study is to evaluate the psychometric properties (reliability, concurrent and longitudinal validity, and responsiveness to change in asthma status) of a new measure of the patient- perceived negative effects of asthma in adults, the Asthma Impact on Quality of Life Scale (A-IQOLS), and to compare its properties with those of a measure of current QoL, the Flanagan Quality of Life Scale (QOLS). We hypothesize that the approach represented by the A-IQOLS will prove superior to that of the QOLS as an out- come measure for clinical research. This research can fill a significant gap in the currently available tools, with consequent benefit to asthma clinical research and, potentially, measurement of patient-centered outcomes in other disease areas.
HHS’ Tracking Accountability in Government Grants System (TAGGS) website provides access to detailed descriptions of grants, loans, aggregated direct payments and other types of financial assistance awarded by the HHS Operating Divisions (OPDIVs) and the Office of the Secretary Staff Divisions (STAFFDIVs).