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Cost-Effectiveness of Food is Medicine Interventions to Improve Diet and Reduce Cardiometabolic Diseases

Award Number: R01HL115189
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/15/2013
PERIOD OF PERFORMANCE END DATE: 05/31/2028

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Cost-Effectiveness of Food is Medicine Interventions to Improve Diet and Reduce Cardiometabolic Diseases - : 5R01HL115189-11 | PI: Mozaffarian, Dariush In the previous period, we have used national and state microsimulation modeling, cost-effectiveness analysis, legal and policy analyses, and real-choice experiments to elucidate the health and cost impacts of specific nutrition-related policies for reducing cardiometabolic diseases (CMD). Our work has identified among the most promising interventions to be Food is Medicine (FIM) strategies: incorporation of food-based nutritional interventions into healthcare to improve food and nutrition security, treat disease, and reduce health differences. Such programs include medically tailored meals or produce prescriptions for patients with specific disease conditions, complemented by nutrition and culinary education. Yet, critical questions remain, each identified and crystallized by our findings and interactions in the prior project period with key stakeholders such as healthcare sector leaders; government officials; patients, doctors, and other care providers; and FIM non-profit providers and private sector entrepreneurs. This new project will leverage the deep learnings and networks established in our prior project period to address the following critical aims: 1) to estimate the health and cost impacts of varying FIM program design options, including key elements of dose ($/mo), food groups, duration, and disease targets; 2) to assess intersections of FIM with other levels of healthcare interventions including (a) coordinated food insecurity screening and SNAP enrollment, and (b) new clinical drug treatments; 3) to investigate the administrative and legal feasibility of pathways for scaling FIM; and 4) to disseminate top findings to relevant scientific, healthcare, legislative, agency, and advocacy stakeholders. To achieve these aims, we will leverage our prior work on the etiologic effects of dietary changes and our validated national microsimulation model to estimate CMD benefits, costs, and cost-effectiveness, and further develop and validate our model to incorporate (a) food insecurity as a risk for health and cost outcomes, (b) the additional, non-CMD QALYs and costs of BMI as a risk; and (c) the health and cost effects of novel drug treatments (e.g., GLP-1 agonists). Effects on health differences will be estimated using both difference-in-difference measures and semi-quantitative measures of disparity. We will perform new landscape, stakeholder, and legal analyses of (a) reimbursement coverage of FIM in Medicare and Medicaid; (b) integration of FIM into rapidly accelerating SDOH modules in EMR and clinical care pathways; and (c) pathways to align consumer education and communication, like SNAP-Ed and FDA food labeling, with a FIM approach. This will include qualitative research into legal authorities and limitations; and research among key stakeholders (e.g. patients/public, private and federal health systems, government) through surveys and mixed methods research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $706,034 )
2026	2026	TRUSTEES OF TUFTS COLLEGE	136 HARRISON AVE	BOSTON	MA	02111	SUFFOLK	USA	Cardiovascular Diseases Research	000	12	7/23/2026	NON-COMPETING CONTINUATION	$706,034
														Subtotal = $706,034

Issue Date FY: 2025 ( Subtotal = $726,754 )
2025	2025	TRUSTEES OF TUFTS COLLEGE	136 HARRISON AVE	BOSTON	MA	02111	SUFFOLK	USA	Cardiovascular Diseases Research	001	11	8/27/2025	NON-COMPETING CONTINUATION	$726,754
2025	2023	TRUSTEES OF TUFTS COLLEGE	136 HARRISON AVE	BOSTON	MA	02111	SUFFOLK	USA	Cardiovascular Diseases Research	000	9	3/24/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $726,754

Issue Date FY: 2024 ( Subtotal = $778,531 )
2024	2024	TRUSTEES OF TUFTS COLLEGE	136 HARRISON AVE	BOSTON	MA	02111	SUFFOLK	USA	Cardiovascular Diseases Research	001	10	8/30/2024	COMPETING CONTINUATION	$778,531
2024	2023	TRUSTEES OF TUFTS COLLEGE	136 HARRISON AVE	BOSTON	MA	02111	SUFFOLK	USA	Cardiovascular Diseases Research	000	9	8/23/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $778,531

Issue Date FY: 2023 ( Subtotal = $691,105 )
2023	2023	TRUSTEES OF TUFTS COLLEGE	136 HARRISON AVE	BOSTON	MA	02111	SUFFOLK	USA	Cardiovascular Diseases Research	001	9	8/2/2023	NON-COMPETING CONTINUATION	$691,105
2023	2023	TRUSTEES OF TUFTS COLLEGE	136 HARRISON AVE	BOSTON	MA	02111	SUFFOLK	USA	Cardiovascular Diseases Research	002	9	9/13/2023	NON-COMPETING CONTINUATION	$0
2023	2022	TRUSTEES OF TUFTS COLLEGE	136 HARRISON AVE	BOSTON	MA	02111	SUFFOLK	USA	Cardiovascular Diseases Research	000	8	5/26/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $691,105

Issue Date FY: 2022 ( Subtotal = $736,745 )
2022	2022	TRUSTEES OF TUFTS COLLEGE	136 HARRISON AVE	BOSTON	MA	02111	SUFFOLK	USA	Cardiovascular Diseases Research	000	8	8/19/2022	NON-COMPETING CONTINUATION	$736,745
														Subtotal = $736,745

Issue Date FY: 2021 ( Subtotal = $768,881 )
2021	2021	TRUSTEES OF TUFTS COLLEGE	136 HARRISON AVE	BOSTON	MA	02111	SUFFOLK	USA	Cardiovascular Diseases Research	000	7	7/29/2021	NON-COMPETING CONTINUATION	$768,881
														Subtotal = $768,881

Issue Date FY: 2020 ( Subtotal = $824,877 )
2020	2020	TRUSTEES OF TUFTS COLLEGE	136 HARRISON AVE	BOSTON	MA	02111	SUFFOLK	USA	Cardiovascular Diseases Research	000	6	7/27/2020	COMPETING CONTINUATION	$824,877
														Subtotal = $824,877

Issue Date FY: 2018 ( Subtotal = -$812 )
2018	2016	TRUSTEES OF TUFTS COLLEGE	136 HARRISON AVE	BOSTON	MA	02111	SUFFOLK	USA	Cardiovascular Diseases Research	000	5	7/31/2018	SUPPLEMENT FOR EXPANSION	-$812
														Subtotal = -$812

Issue Date FY: 2016 ( Subtotal = $798,073 )
2016	2016	TUFTS UNIVERSITY	169 HOLLAND ST, 2ND FLOOR	SOMERVILLE	MA	02144	MIDDLESEX	USA	Cardiovascular Diseases Research	000	5	4/1/2016	NON-COMPETING CONTINUATION	$720,787
2016	2016	TUFTS UNIVERSITY	169 HOLLAND ST, 2ND FLOOR	SOMERVILLE	MA	02144	MIDDLESEX	USA	Cardiovascular Diseases Research	001	5	5/2/2016	SUPPLEMENT FOR EXPANSION	$77,286
														Subtotal = $798,073

Issue Date FY: 2015 ( Subtotal = $715,197 )
2015	2015	TUFTS UNIVERSITY	169 HOLLAND ST, 2ND FLOOR	SOMERVILLE	MA	02144	MIDDLESEX	USA	Cardiovascular Diseases Research	000	4	3/20/2015	NON-COMPETING CONTINUATION	$715,197
														Subtotal = $715,197

Issue Date FY: 2014 ( Subtotal = $720,503 )
2014	2014	TUFTS UNIVERSITY	169 HOLLAND ST, 2ND FLOOR	SOMERVILLE	MA	02144	MIDDLESEX	USA	Cardiovascular Diseases Research	002	3	9/5/2014	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$704,160
2014	2014	HARVARD UNIVERSITY, SCHOOL OF PUBLIC HEALTH	55 SHATTUCK STREET	BOSTON	MA	02115	SUFFOLK	USA	Cardiovascular Diseases Research	000	2	5/16/2014	NON-COMPETING CONTINUATION	$720,503
2014	2014	HARVARD UNIVERSITY, SCHOOL OF PUBLIC HEALTH	55 SHATTUCK STREET	BOSTON	MA	02115	SUFFOLK	USA	Cardiovascular Diseases Research	001	2	9/5/2014	NON-COMPETING CONTINUATION	-$704,160
														Subtotal = $720,503

Issue Date FY: 2013 ( Subtotal = $731,283 )
2013	2013	HARVARD UNIVERSITY, SCHOOL OF PUBLIC HEALTH	55 SHATTUCK STREET	BOSTON	MA	02115	SUFFOLK	USA	Cardiovascular Diseases Research	000	1	8/9/2013	NEW	$731,283
														Subtotal = $731,283

Grand Total All Awards = $8,197,171

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Cost-Effectiveness of Food is Medicine Interventions to Improve Diet and Reduce Cardiometabolic Diseases

Award Number: R01HL115189

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/15/2013

PERIOD OF PERFORMANCE END DATE: 05/31/2028

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