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IMPROVING VENTILATOR MANAGEMENT AND PREVENTING INJURY TO PATIENTS WITH ARF

Award Number: R01HL067939
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 07/15/2001
PERIOD OF PERFORMANCE END DATE: 06/30/2012

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IMPROVING VENTILATOR MANAGEMENT AND PREVENTING INJURY TO PATIENTS WITH ARF - DESCRIPTION (provided by applicant): Competing renewal of, Improving Ventilator Management And Preventing Injury To Patients With Acute Lung Injury and Acute Respiratory Distress Syndrome, we propose building on our work developing a succesful intervention to implement lung protective ventilation in patients with acute lung injury at 10 local hospitals in King County Washington by extending its geographic, clinical, and scientific scope. Acute respiratory failure is a heterogeneous set of disorders requiring ventilatory support including acute lung injury, pneumonia, and exacerbations of chronic lung disease with mortality rates that range from 30% to over 60%. Conservative estimates suggest that acute respiratory failure accounts for 100,000 deaths and over $2.5 billion in medical spending each year in the United States. Effective interventions to reduce this mortality and morbidity are known but are not routinely implemented. These include (1) a lung protective ventilation protocol that reduces mortality in acute lung injury, (2) a respiratory therapist protocol incorporating a daily spontaneous breathing trial that reduces duration of mechanical ventilation, (3) a nursing protocol for sedation that incorporates a daily interruption of sedating medication that reduces duration of mechanical ventilation, (4) semirecumbent positioning that reduces the incidence of ventilator associated pneumonia, (5) noninvasive ventilation for COPD exacerbation that reduces mortality compared to endotracheal intubation. We will partner with Cerner Corporation, a leading provider of healthcare informatics solutions, to accomplish 3 specific aims: (1) To identify barriers and facilitators to implementing guideline based care of mechanically ventilated patients with acute respiratory failure, (2) To develop and pilot a web-based, interactive, multi- media educational and feedback intervention to implement guideline based care of mechanically ventilated patients with acute respiratory failure, and (3) To test the effectiveness of a web-based, interactive, multi- media educational and feedback intervention to implement guideline based care of mechanically ventilated patients with acute respiratory failure in a national network of 40 community hospitals.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2011 ( Subtotal = $0 )
2011	2009	SUNNYBROOK HEALTH SCIENCES CENTRE	2075 BAYVIEW AVENUE	TORONTO				CAN	Lung Diseases Research	000	8	6/7/2011	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2009 ( Subtotal = $514,014 )
2009	2009	SUNNYBROOK & WOMENS COLL HLTH SCIS CTR	2075 Bayview Avenue	TORONTO				CAN	Lung Diseases Research	000	8	7/20/2009	NON-COMPETING CONTINUATION	$514,014
														Subtotal = $514,014

Issue Date FY: 2007 ( Subtotal = $710,559 )
2007	2007	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Lung Diseases Research	000	6	9/24/2007	NON-COMPETING CONTINUATION	$710,559
														Subtotal = $710,559

Issue Date FY: 2006 ( Subtotal = $690,916 )
2006	2006	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98105	KING	USA	Lung Diseases Research	000	5	9/15/2006	COMPETING CONTINUATION	$690,916
														Subtotal = $690,916

Issue Date FY: 2004 ( Subtotal = $593,887 )
2004	2004	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98195	KING	USA	Lung Diseases Research	000	4	5/26/2004	NON-COMPETING CONTINUATION	$593,887
														Subtotal = $593,887

Issue Date FY: 2003 ( Subtotal = $576,591 )
2003	2003	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98195	KING	USA	Lung Diseases Research	000	3	5/28/2003	NON-COMPETING CONTINUATION	$576,591
														Subtotal = $576,591

Issue Date FY: 2002 ( Subtotal = $559,795 )
2002	2002	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98195	KING	USA	Lung Diseases Research	000	2	6/3/2002	NON-COMPETING CONTINUATION	$559,795
														Subtotal = $559,795

Issue Date FY: 2001 ( Subtotal = $564,793 )
2001	2001	UNIVERSITY OF WASHINGTON	3917 UNIVERSITY WAY NE	SEATTLE	WA	98195	KING	USA	Lung Diseases Research	000	1	7/9/2001	NEW	$564,793
														Subtotal = $564,793

Grand Total All Awards = $4,210,555

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IMPROVING VENTILATOR MANAGEMENT AND PREVENTING INJURY TO PATIENTS WITH ARF

Award Number: R01HL067939

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 07/15/2001

PERIOD OF PERFORMANCE END DATE: 06/30/2012

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