Friday, March 14, 2025 3/14/2025

Rat Genome Database

Award Number: R01HL064541
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By:

View Award Abstract

Project Summary The Rat Genome Database (RGD) has evolved substantially from a catalog of rat genetic markers, maps, and genes to a comprehensive resource with multiple genomic data types, extensive disease and phenotype annotations, and tools to effectively mine, analyze and visualize the available data. The goal of RGD is to enable investigators in their hypothesis-driven research. Leveraging its robust and flexible infrastructure, RGD has added data from human and other important human disease model organisms to enhance its translational aspect. RGD is also one of the founding members of the Alliance of Genome Resources (Alliance), a consortium of the major model organism databases focused on harmonizing and presenting cross-species information. Since 2019, there has been an exciting reinvigoration in the rat genomics community and research. Through collaboration with the Wellcome Sanger Institute, a new and vastly improved rat reference genome (mRatBN7.2) has been generated and released, and RGD joined the Genome Reference Consortium (GRC) to curate it. Several complementary NIH-funded projects focused on generating whole genome, transcriptome, and epigenome sequencing datasets are underway in numerous rat strains representing human disease models; several strains, including key models of heart, lung, blood and sleep disorders will have strain-specific, muli-omic data and de novo genome assemblies. RGD has the unique opportunity to be the center of data integration for these new, unique datasets, the overall theme of this renewal. To continue increasing the value of RGD and build on the investments made by the NIH and other international funding bodies in rat research, we will develop an extensive ecosystem for integration of multi-omics and biological data in the rat as a model of common human complex disease and create a comprehensive comparative species platform to predict precision preclinical human disease models for further study by research community.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $1,741,679 )
2025	2025	THE MEDICAL COLLEGE OF WISCONSIN, INC.	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	26	12/25/2024	NON-COMPETING CONTINUATION	$1,741,679
2025	2023	THE MEDICAL COLLEGE OF WISCONSIN, INC.	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	002	24	1/23/2025	COMPETING CONTINUATION	$1,083,033
2025	2022	THE MEDICAL COLLEGE OF WISCONSIN, INC.	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	001	23	1/23/2025	NON-COMPETING CONTINUATION	-$1,083,033
														Subtotal = $1,741,679

Issue Date FY: 2024 ( Subtotal = $1,902,667 )
2024	2024	THE MEDICAL COLLEGE OF WISCONSIN, INC.	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	25	12/14/2023	NON-COMPETING CONTINUATION	$1,747,349
2024	2024	THE MEDICAL COLLEGE OF WISCONSIN, INC.	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	001	25	6/13/2024	NON-COMPETING CONTINUATION	$155,318
														Subtotal = $1,902,667

Issue Date FY: 2023 ( Subtotal = $2,008,998 )
2023	2023	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	001	24	1/9/2023	COMPETING CONTINUATION	$2,008,998
2023	2022	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	23	12/31/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,008,998

Issue Date FY: 2022 ( Subtotal = $2,081,534 )
2022	2022	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	001	23	6/29/2022	NON-COMPETING CONTINUATION	$208,154
2022	2022	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	23	12/25/2021	NON-COMPETING CONTINUATION	$1,873,380
														Subtotal = $2,081,534

Issue Date FY: 2021 ( Subtotal = $2,135,569 )
2021	2021	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	001	22	5/14/2021	NON-COMPETING CONTINUATION	$213,557
2021	2021	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	22	1/10/2021	NON-COMPETING CONTINUATION	$1,922,012
														Subtotal = $2,135,569

Issue Date FY: 2020 ( Subtotal = $2,132,754 )
2020	2020	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	002	21	3/19/2020	NON-COMPETING CONTINUATION	$0
2020	2020	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	21	12/15/2019	NON-COMPETING CONTINUATION	$2,026,116
2020	2020	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	001	21	1/28/2020	NON-COMPETING CONTINUATION	$106,638
														Subtotal = $2,132,754

Issue Date FY: 2019 ( Subtotal = $2,232,697 )
2019	2019	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	20	1/4/2019	COMPETING CONTINUATION	$2,232,697
2019	2019	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	002	20	4/25/2019	COMPETING CONTINUATION	$583,489
2019	2018	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	001	19	4/25/2019	NON-COMPETING CONTINUATION	-$583,489
														Subtotal = $2,232,697

Issue Date FY: 2018 ( Subtotal = $1,929,247 )
2018	2018	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	001	19	8/2/2018	NON-COMPETING CONTINUATION	$38,585
2018	2018	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	19	1/13/2018	NON-COMPETING CONTINUATION	$1,890,662
														Subtotal = $1,929,247

Issue Date FY: 2017 ( Subtotal = $1,929,875 )
2017	2017	MEDICAL COLLEGE OF WISCONSIN, INC., THE	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	18	12/16/2016	NON-COMPETING CONTINUATION	$1,929,875
														Subtotal = $1,929,875

Issue Date FY: 2016 ( Subtotal = $1,920,225 )
2016	2016	MEDICAL COLLEGE OF WISCONSIN, INC	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	17	12/18/2015	NON-COMPETING CONTINUATION	$1,893,668
2016	2016	MEDICAL COLLEGE OF WISCONSIN, INC	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	001	17	2/10/2016	NON-COMPETING CONTINUATION	$26,557
														Subtotal = $1,920,225

Issue Date FY: 2015 ( Subtotal = $2,152,398 )
2015	2015	MEDICAL COLLEGE OF WISCONSIN, INC	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	16	1/12/2015	COMPETING CONTINUATION	$2,009,704
2015	2015	MEDICAL COLLEGE OF WISCONSIN, INC	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	003	16	9/16/2015	COMPETING CONTINUATION	$0
2015	2015	MEDICAL COLLEGE OF WISCONSIN, INC	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	002	16	9/15/2015	SUPPLEMENT FOR EXPANSION	$142,694
2015	2014	MEDICAL COLLEGE OF WISCONSIN, INC	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	001	15	1/12/2015	NON-COMPETING CONTINUATION	$0
														Subtotal = $2,152,398

Issue Date FY: 2014 ( Subtotal = $1,813,237 )
2014	2014	MEDICAL COLLEGE OF WISCONSIN, INC	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	15	11/26/2013	NON-COMPETING CONTINUATION	$1,665,218
2014	2014	MEDICAL COLLEGE OF WISCONSIN, INC	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	001	15	5/8/2014	NON-COMPETING CONTINUATION	$148,019
														Subtotal = $1,813,237

Issue Date FY: 2013 ( Subtotal = $1,761,431 )
2013	2013	MEDICAL COLLEGE OF WISCONSIN, INC	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	001	14	7/10/2013	NON-COMPETING CONTINUATION	$96,213
2013	2013	MEDICAL COLLEGE OF WISCONSIN, INC	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	14	11/30/2012	NON-COMPETING CONTINUATION	$1,665,218
														Subtotal = $1,761,431

Issue Date FY: 2012 ( Subtotal = $1,850,241 )
2012	2012	MEDICAL COLLEGE OF WISCONSIN, INC	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	13	12/22/2011	NON-COMPETING CONTINUATION	$1,618,514
2012	2012	MEDICAL COLLEGE OF WISCONSIN, INC	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	001	13	4/28/2012	NON-COMPETING CONTINUATION	$231,727
														Subtotal = $1,850,241

Issue Date FY: 2011 ( Subtotal = $1,850,241 )
2011	2011	MEDICAL COLLEGE OF WISCONSIN, INC	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	000	12	12/22/2010	NON-COMPETING CONTINUATION	$1,695,538
2011	2011	MEDICAL COLLEGE OF WISCONSIN, INC	8701 WATERTOWN PLANK RD	MILWAUKEE	WI	53226	MILWAUKEE	USA	Cardiovascular Diseases Research	001	12	8/3/2011	NON-COMPETING CONTINUATION	$154,703
														Subtotal = $1,850,241

Issue Date FY: 2010 ( Subtotal = $1,791,904 ) (Continued on the next page)
Grand Total All Awards = $49,564,394

Page 1 of 2 (73 items)12

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Rat Genome Database

Award Number: R01HL064541

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer