Wednesday, January 15, 2025 1/15/2025

Improving seated postural control and upper extremity function in bilateral CP with a robotic Trunk-Support-Trainer (TruST)

Award Number: R01HD101903
ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Children with moderate to severe bilateral CP have poor upper extremity abilities and segmental trunk control deficits. Their independent functional sitting is impaired with decreased participation in leisure activities, education involvement. Therefore, promoting independent sitting and improving postural and upper extremity abilities are critical to the health and functional independence of children with moderate-to-severe bilateral CP (GMFCS III-IV). Despite significant strides in upper extremity treatments of children with milder (unilateral) CP, there is limited evidence supporting efficacy of treatments targeting seated postural control in bilateral CP. Recent robotic equipment allows clinicians to address engagement, repetition, and intensity to practice task-oriented movements in CP. In this vein, we postulate that robotics can offer a unique platform to provide efficient motor learning-based training in children with bilateral CP by implementing postural skill progression. Our team has developed a unique motorized Trunk- Support-Trainer (TruST) to engage children in play-oriented practice with skill progression. TruST creates a customized donut-like force field at the region of the torso where balance is lost to provide active assistance beyond the sitting stability limits through a belt. The training is based on principles of motor learning, including skill progression. The overall goal of this work is to develop an evidence-based strategy to promote functional independent sitting, maximize seated postural and upper extremity abilities, and improve sitting- related ADLs. Our central hypothesis is that sitting and reaching benefits can be achieved when a motor learning-based postural intervention is combined with postural-skill progression delivered via TruST in comparison to a static trunk support. The innovation of this proposal, (RFA-HD-20- 005, ‘Pediatric Rehabilitation’) lies in the fusion of evidence-based clinical practice and novel robotics with TruST. The result is a training paradigm where children with bilateral CP can receive motor learning-based postural training in addition to postural skill progression that is tailored to the child’s postural stability in sitting. If our hypotheses are supported, the TruST-intervention will be a unique therapeutic solution for children with CP GMFCS III-IV to acquire and improve independent functional sitting.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $572,202 )
2024	2024	THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK	615 W 131ST ST	NEW YORK	NY	10027	NEW YORK	USA	Child Health and Human Development Extramural Research	002	5	9/4/2024	NON-COMPETING CONTINUATION	$572,202
2024	2023	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	202 LOW LIBRARY 535 W 116 ST MC 4309,	NEW YORK	NY	10027	NEW YORK	USA	Child Health and Human Development Extramural Research	001	4	10/26/2023	SUPPLEMENT FOR EXPANSION	$0
2024	2023	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	202 LOW LIBRARY 535 W 116 ST MC 4309,	NEW YORK	NY	10027	NEW YORK	USA	Child Health and Human Development Extramural Research	000	4	10/26/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $572,202

Issue Date FY: 2023 ( Subtotal = $734,836 )
2023	2023	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	202 LOW LIBRARY 535 W 116 ST MC 4309,	NEW YORK	NY	10027	NEW YORK	USA	Child Health and Human Development Extramural Research	002	4	8/26/2023	SUPPLEMENT FOR EXPANSION	$85,250
2023	2023	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	202 LOW LIBRARY 535 W 116 ST MC 4309,	NEW YORK	NY	10027	NEW YORK	USA	Child Health and Human Development Extramural Research	003	4	8/27/2023	NON-COMPETING CONTINUATION	$0
2023	2023	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	202 LOW LIBRARY 535 W 116 ST MC 4309,	NEW YORK	NY	10027	NEW YORK	USA	Child Health and Human Development Extramural Research	001	4	8/21/2023	NON-COMPETING CONTINUATION	$590,321
2023	2023	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	202 LOW LIBRARY 535 W 116 ST MC 4309,	NEW YORK	NY	10027	NEW YORK	USA	Child Health and Human Development Extramural Research	000	3	1/6/2023	SUPPLEMENT FOR EXPANSION	$59,265
														Subtotal = $734,836

Issue Date FY: 2022 ( Subtotal = $602,290 )
2022	2022	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE	202 LOW LIBRARY 535 W 116 ST MC 4309,	NEW YORK	NY	10027	NEW YORK	USA	Child Health and Human Development Extramural Research	000	3	7/28/2022	NON-COMPETING CONTINUATION	$602,290
														Subtotal = $602,290

Issue Date FY: 2021 ( Subtotal = $596,462 )
2021	2021	REDACTED DUE TO PII		NEW YORK	NY	10027	NEW YORK	USA	Child Health and Human Development Extramural Research	000	2	8/10/2021	NON-COMPETING CONTINUATION	$596,462
														Subtotal = $596,462

Issue Date FY: 2020 ( Subtotal = $616,206 )
2020	2020	REDACTED DUE TO PII		NEW YORK	NY	10027	NEW YORK	USA	Child Health and Human Development Extramural Research	001	1	8/26/2020	NEW	$3,882
2020	2020	REDACTED DUE TO PII		NEW YORK	NY	10027	NEW YORK	USA	Child Health and Human Development Extramural Research	000	1	7/20/2020	NEW	$612,324
														Subtotal = $616,206

Grand Total All Awards = $3,121,996

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Improving seated postural control and upper extremity function in bilateral CP with a robotic Trunk-Support-Trainer (TruST)

Award Number: R01HD101903

ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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