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Leveraging data to identify opportunities to address insecure care connections and poor health outcomes among people living with HIV

Award Number: R01HD098013
ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Leveraging data to identify opportunities to address insecure care connections and poor health outcomes among people living with HIV - SUMMARY/ABSTRACT To determine correlates of poor vs. good HIV outcomes among people living with HIV (PLWH), researchers have focused on clinical data. Hence, there is limited understanding of non‐clinical correlates and migration patterns of PLWH who have insecure (or fragmented) connections with the care system. This proposal will leverage our unique access to clinical and non‐clinical data to measure HIV care outcomes and identify intervention opportunities to address insecure connection to care and poor outcomes inPLWH. Our team has individually linked data from the Enhanced HIV/AIDS Reporting System (eHARS), the national HIV surveillance database, with other public health, clinical, and criminal justice data. We use these data to conduct population‐level epidemiology of over 10,000 PLWH in Marion County (Indianapolis), Indiana between 2000 and the present. We propose to link these data with social determinants of health data within the Indiana Management Performance Hub (MPH), a collaborative state government data‐sharing hub. MPH data will complement our rich data repository by adding socioeconomic, household, and neighborhood characteristics, social service utilization (welfare, food stamps, etc.), and mental health data for PLWH. Given the complex intersection of social determinants of health and migration within and between counties (e.g., because of housing insecurity or discontinuity of insurance coverage), we will also investigate how migration relates to insecure care connections and poor outcomes. Our access to these data sources will permit us to focus on both social determinants of health and migration, and will provide us with the unprecedented ability (1) to investigate how these factors relate to HIV outcomes over time, and (2) to identify intervention opportunities (times and places) to improve connection to care and clinical outcomes in PLWH. The objective of our research is to investigate correlates, and opportunities for improvement, of poor HIV health outcomes in Marion County (Indianapolis), Indiana. The hypothesis is that identification of correlates of poor retention in care and of poor viral suppression will identify opportunities to improve health outcomes for PLWH who are insecurely connected to care. We aim to (1) Analyze patterns in social services utilization among PLWH to (a) understand correlates of poor HIV outcomes and (b) identify non‐clinical opportunities for intervention; (2) Determine if within‐county and between‐county migration patterns after diagnosis predict poor HIV care outcomes; (2a) Identify demographic, socioeconomic, life‐course, and contextual factors associated with worse HIV outcomes among those who migrate; and (3) Develop a model to extend the utility of eHARS data for longitudinal research and public health practice, with guidance from a stakeholder advisory panel. Results from this project will inform a subsequent R01 application assessing whether supplemental wrap‐around and outreach services for those identified at higher risk due to non‐clinical service utilization and migration patterns improve care and outcomes of PLWH.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $735,505 )
2025	2025	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Child Health and Human Development Extramural Research	000	5	2/28/2025	NON-COMPETING CONTINUATION	$735,505
														Subtotal = $735,505

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Child Health and Human Development Extramural Research	000	4	4/3/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $748,573 )
2023	2023	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Child Health and Human Development Extramural Research	000	4	3/6/2023	NON-COMPETING CONTINUATION	$748,573
														Subtotal = $748,573

Issue Date FY: 2022 ( Subtotal = $759,329 )
2022	2022	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Child Health and Human Development Extramural Research	000	3	3/9/2022	NON-COMPETING CONTINUATION	$683,394
2022	2022	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Child Health and Human Development Extramural Research	001	3	4/25/2022	NON-COMPETING CONTINUATION	$75,935
														Subtotal = $759,329

Issue Date FY: 2021 ( Subtotal = $768,716 )
2021	2021	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Child Health and Human Development Extramural Research	000	2	4/12/2021	NON-COMPETING CONTINUATION	$768,716
														Subtotal = $768,716

Issue Date FY: 2020 ( Subtotal = $787,410 )
2020	2020	TRUSTEES OF INDIANA UNIVERSITY	980 INDIANA AVE RM 2232	INDIANAPOLIS	IN	46202	MARION	USA	Child Health and Human Development Extramural Research	000	1	4/13/2020	NEW	$787,410
														Subtotal = $787,410

Grand Total All Awards = $3,799,533

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Leveraging data to identify opportunities to address insecure care connections and poor health outcomes among people living with HIV

Award Number: R01HD098013

ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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