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Rethinking Electronic Fetal Monitoring to Improve Perinatal Outcomes and Reduce Frequency of Operative Vaginal and Cesarean Deliveries

Award Number: R01HD097188
ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 05/10/2019
PERIOD OF PERFORMANCE END DATE: 03/31/2025

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Rethinking Electronic Fetal Monitoring to Improve Perinatal Outcomes and Reduce Frequency of Operative Vaginal and Cesarean Deliveries - The essential role of electronic fetal monitoring (EFM) during labor is to prevent adverse outcomes due to fetal hypoxia and ischemia. Its established weaknesses include: 1) the obstetrician’s highly subjective visual interpretations of the signal patterns and 2) the widespread use of unproven surrogates for relevant fetal hypoxic and/or ischemic injury such as umbilical arterial pH, intrapartum stillbirth, newborn Apgar scores and neonatal seizures. This technology over the past 50 years has not been shown to decrease stillbirths or reduce the numbers of infants with cerebral palsy. EFM as it is presently used in the clinical setting has been associated with an extraordinary increase in the use of operative vaginal delivery and cesarean delivery. No functional algorithm has yet been developed that integrates clinical data collected in the antepartum period and during labor and any other patient specific data with the results of EFM. The main objective of the proposed research is to use recent breakthroughs in machine learning to drive the development of predictive analytics to support and improve the interpretation of EFM data, especially under real world conditions and in real time where clinicians must make timely decisions about interventions to prevent adverse outcomes. It is anticipated that the proposed research will result in significantly decreased use of operative vaginal delivery and cesarean delivery while more precisely defining the fetus at risk for developing metabolic acidosis and long term neurologic injury.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2023	THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK	W5510 FRANKS MELVILLE MEMORIAL LIBRARY	STONY BROOK	NY	11794	SUFFOLK	USA	Child Health and Human Development Extramural Research	000	5	8/21/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $526,934 )
2023	2023	THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK	W5510 FRANKS MELVILLE MEMORIAL LIBRARY	STONY BROOK	NY	11794	SUFFOLK	USA	Child Health and Human Development Extramural Research	000	5	4/10/2023	NON-COMPETING CONTINUATION	$526,934
														Subtotal = $526,934

Issue Date FY: 2022 ( Subtotal = $663,252 )
2022	2022	RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, THE	WEST 5510 FRANKS MELVILLE MEMORIAL LIBRARY	STONY BROOK	NY	11794	SUFFOLK	USA	Child Health and Human Development Extramural Research	002	4	5/24/2022	NON-COMPETING CONTINUATION	$663,252
2022	2021	RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, THE	WEST 5510 FRANKS MELVILLE MEMORIAL LIBRARY	STONY BROOK	NY	11794	SUFFOLK	USA	Child Health and Human Development Extramural Research	001	3	3/25/2022	NON-COMPETING CONTINUATION	$0
2022	2020	RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, THE	WEST 5510 FRANKS MELVILLE MEMORIAL LIBRARY	STONY BROOK	NY	11794	SUFFOLK	USA	Child Health and Human Development Extramural Research	000	2	3/11/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $663,252

Issue Date FY: 2021 ( Subtotal = $663,252 )
2021	2021	RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, THE	WEST 5510 FRANKS MELVILLE MEMORIAL LIBRARY	STONY BROOK	NY	11794	SUFFOLK	USA	Child Health and Human Development Extramural Research	000	3	3/30/2021	NON-COMPETING CONTINUATION	$663,252
														Subtotal = $663,252

Issue Date FY: 2020 ( Subtotal = $676,787 )
2020	2020	RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, THE	WEST 5510 FRANKS MELVILLE MEMORIAL LIBRARY	STONY BROOK	NY	11794	SUFFOLK	USA	Child Health and Human Development Extramural Research	000	2	4/14/2020	NON-COMPETING CONTINUATION	$676,787
														Subtotal = $676,787

Issue Date FY: 2019 ( Subtotal = $676,787 )
2019	2019	RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK, THE	WEST 5510 FRANKS MELVILLE MEMORIAL LIBRARY	STONY BROOK	NY	11794	SUFFOLK	USA	Child Health and Human Development Extramural Research	000	1	5/10/2019	NEW	$676,787
														Subtotal = $676,787

Grand Total All Awards = $3,207,012

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Rethinking Electronic Fetal Monitoring to Improve Perinatal Outcomes and Reduce Frequency of Operative Vaginal and Cesarean Deliveries

Award Number: R01HD097188

ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 05/10/2019

PERIOD OF PERFORMANCE END DATE: 03/31/2025

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