Wednesday, August 20, 2025 8/20/2025

Noninvasive modulation of perception and cognition with flicker induced response modulation.

Award Number: R01EY032744
ORGANIZATION: NATIONAL EYE INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 05/01/2021
PERIOD OF PERFORMANCE END DATE: 04/30/2026

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Noninvasive modulation of perception and cognition with flicker induced response modulation. - Project Summary This project investigates the use of repetitive visual stimulation as a tool to improve visual cognition. Surprisingly, the repeated presentation of simple visual patterns can result in long-term plasticity, reflected in increased neural responses, but also in behavioral improvements that last for hours, even days. In current approaches using RVS, however, these improvements are limited to the specific, repeated patterns; this limits the practical usefulness of RVS. The proposed project builds on recent findings in the nonhuman primate demonstrating widespread and general increases in neural responses after the repeated presentation of a uniform grey screen with sinusoidally modulated luminance. The first aim is to show, using EEG, that such long-lasting increases in neural responses also occur in the human brain. The second aim is to determine which aspects of visual cognition are improved by this boost in neural responses. The project will assess improvements in low-level vision such as detection and visual acuity, but also higher-level visual processes such as visuospatial attention, and visual working memory. The pilot data already show widespread neural changes in the human brain and substantial behavioral improvements in, for instance, visual acuity. A successful tool to improve visual cognition would have a significant impact, as it could be used therapeutically in low vision conditions (e.g., amblyopia), but also in the elderly or healthy human subjects, to deliver a boost in performance.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $392,500 )
2025	2025	RUTGERS, THE STATE UNIVERSITY	123 WASHINGTON ST	NEWARK	NJ	07102	ESSEX	USA	Vision Research	000	5	8/4/2025	NON-COMPETING CONTINUATION	$392,500
														Subtotal = $392,500

Issue Date FY: 2024 ( Subtotal = $392,500 )
2024	2024	RUTGERS, THE STATE UNIVERSITY	123 WASHINGTON ST	NEWARK	NJ	07102	ESSEX	USA	Vision Research	000	4	5/13/2024	NON-COMPETING CONTINUATION	$392,500
														Subtotal = $392,500

Issue Date FY: 2023 ( Subtotal = $392,500 )
2023	2023	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	123 WASHINGTON ST STE 510	NEWARK	NJ	07102	ESSEX	USA	Vision Research	000	3	4/27/2023	NON-COMPETING CONTINUATION	$392,500
														Subtotal = $392,500

Issue Date FY: 2022 ( Subtotal = $380,725 )
2022	2022	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	123 WASHINGTON ST STE 510	NEWARK	NJ	07102	ESSEX	USA	Vision Research	001	2	6/27/2022	NON-COMPETING CONTINUATION	$0
2022	2022	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	123 WASHINGTON ST STE 510	NEWARK	NJ	07102	ESSEX	USA	Vision Research	000	2	5/4/2022	NON-COMPETING CONTINUATION	$380,725
														Subtotal = $380,725

Issue Date FY: 2021 ( Subtotal = $392,084 )
2021	2021	RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY	123 WASHINGTON ST STE 510	NEWARK	NJ	07102	ESSEX	USA	Vision Research	000	1	4/28/2021	NEW	$392,084
														Subtotal = $392,084

Grand Total All Awards = $1,950,309

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Noninvasive modulation of perception and cognition with flicker induced response modulation.

Award Number: R01EY032744

ORGANIZATION: NATIONAL EYE INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 05/01/2021

PERIOD OF PERFORMANCE END DATE: 04/30/2026

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