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Anatomical and functional organization of inter-areal feedback circuits in the visual cortex, and their impact on neuronal responses

Award Number: R01EY026812
ORGANIZATION: NATIONAL EYE INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 06/01/2016
PERIOD OF PERFORMANCE END DATE: 05/31/2026

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Anatomical and functional organization of inter-areal feedback circuits in the visual cortex, and their impact on neuronal responses - SUMMARY The goals and specific aims of the present Administrative Supplement application are unchanged with respect to the parent R01 award. Here we request additional funds for unanticipated expenses within the original scope of the project. In the original application we proposed to investigate the anatomical and functional organization of V2-to-V1 feedback (FB) circuits arising from, and terminating in specific cortical layers in macaque monkeys. At the time we submitted the parent R01 application, we could obtain non-naïve macaque monkeys at a cost of approximately $2,000 per animal. Due to a country-wide shortage of macaque monkeys, we can no longer obtain these non-naïve monkeys, and the current price for a cynomolgus macaque is $23,500 per animal (including shipping). This requires significant additional costs, which we cannot cover with the funds awarded. Therefore, with the present Supplement application we request additional funds to cover the increased costs of the animals, which are necessary to carry out the proposed studies.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $692,478 )
2024	2024	UNIVERSITY OF UTAH	201 PRESIDENTS CIR	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	001	9	5/22/2024	NON-COMPETING CONTINUATION	$427,598
2024	2024	UNIVERSITY OF UTAH	201 PRESIDENTS CIR	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	000	8	12/4/2023	SUPPLEMENT FOR EXPANSION	$264,880
														Subtotal = $692,478

Issue Date FY: 2023 ( Subtotal = $437,178 )
2023	2023	UNIVERSITY OF UTAH	201 PRESIDENTS CIR	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	000	8	5/15/2023	NON-COMPETING CONTINUATION	$437,178
														Subtotal = $437,178

Issue Date FY: 2022 ( Subtotal = $455,298 )
2022	2022	UNIVERSITY OF UTAH, THE	201 PRESIDENTS CIR	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	002	7	6/6/2022	NON-COMPETING CONTINUATION	$455,298
2022	2021	UNIVERSITY OF UTAH, THE	201 PRESIDENTS CIR	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	001	6	10/30/2021	COMPETING CONTINUATION	$2,105
2022	2020	UNIVERSITY OF UTAH, THE	201 PRESIDENTS CIR	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	000	5	10/30/2021	NON-COMPETING CONTINUATION	-$2,105
														Subtotal = $455,298

Issue Date FY: 2021 ( Subtotal = $451,753 )
2021	2021	UNIVERSITY OF UTAH, THE	201 PRESIDENTS CIR	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	001	6	5/21/2021	COMPETING CONTINUATION	$451,753
2021	2020	UNIVERSITY OF UTAH, THE	201 PRESIDENTS CIR	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	000	5	5/20/2021	NON-COMPETING CONTINUATION	$0
														Subtotal = $451,753

Issue Date FY: 2020 ( Subtotal = $389,942 )
2020	2020	UNIVERSITY OF UTAH, THE	201 PRESIDENTS CIR	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	000	5	3/10/2020	NON-COMPETING CONTINUATION	$389,942
														Subtotal = $389,942

Issue Date FY: 2019 ( Subtotal = $435,272 )
2019	2019	UNIVERSITY OF UTAH, THE	201 S PRESIDENT CIRCLE RM 408	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	000	4	3/4/2019	NON-COMPETING CONTINUATION	$435,272
														Subtotal = $435,272

Issue Date FY: 2018 ( Subtotal = $435,272 )
2018	2018	UNIVERSITY OF UTAH, THE	201 S PRESIDENT CIRCLE RM 408	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	001	3	5/24/2018	NON-COMPETING CONTINUATION	$43,528
2018	2018	UNIVERSITY OF UTAH, THE	201 S PRESIDENT CIRCLE RM 408	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	000	3	3/8/2018	NON-COMPETING CONTINUATION	$391,744
														Subtotal = $435,272

Issue Date FY: 2017 ( Subtotal = $435,272 )
2017	2017	UNIVERSITY OF UTAH, THE	201 S PRESIDENT CIRCLE RM 408	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	001	2	7/7/2017	NON-COMPETING CONTINUATION	$43,528
2017	2017	UNIVERSITY OF UTAH, THE	201 S PRESIDENT CIRCLE RM 408	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	000	2	2/20/2017	NON-COMPETING CONTINUATION	$391,744
														Subtotal = $435,272

Issue Date FY: 2016 ( Subtotal = $568,857 )
2016	2016	UNIVERSITY OF UTAH	201 SOUTH PRESIDENT`S CIRCLE	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	001	1	9/19/2016	SUPPLEMENT FOR EXPANSION	$109,999
2016	2016	UNIVERSITY OF UTAH	201 SOUTH PRESIDENT`S CIRCLE	SALT LAKE CITY	UT	84112	SALT LAKE	USA	Vision Research	000	1	2/26/2016	NEW	$458,858
														Subtotal = $568,857

Grand Total All Awards = $4,301,322

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Anatomical and functional organization of inter-areal feedback circuits in the visual cortex, and their impact on neuronal responses

Award Number: R01EY026812

ORGANIZATION: NATIONAL EYE INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 06/01/2016

PERIOD OF PERFORMANCE END DATE: 05/31/2026

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