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Efficient Bioremediation of Environmentally Persistent Contaminants with Nanomaterial-Fungus Framework (NFF)

Award Number: R01ES032708
ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 01/01/2021
PERIOD OF PERFORMANCE END DATE: 10/31/2026

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Efficient Bioremediation of Environmentally Persistent Contaminants with Nanomaterial-Fungus Framework (NFF) - Project Summary The recalcitrant and harmful chemicals such as PFASs (per- and polyfluoroalkyl substances), endangers the environmental, wild-life, and human health profoundly. Among different strategies, bioremediation was established as an effective and reliable solution for remediating persistent environmental contaminants like PFASs. Fungi, such as basidiomycetes (i.e. white rot fungi) are used in bioremediation of PFAS for their strong extracellular biocatalytic capacity with great promise. However, several factors limit commercial applications: 1) need for nutrient addition as the carbon source for the microbe; 2) need to immobilize fungus biomass as pellets to prevent fungus dispersion onto reactor wall; 3) bacterial competition; 4) low efficiency due to the low chemical availability to the fungal mycelium and slow fungus growth. The proposed research will address the imminent challenges of remediating persistent and toxic environmental contaminants using the uniquely designed Nanomaterial-Fungus Framework (NFF). The NFF is a system that novel nano-materials create a biomimic scaffold where fungus can grow, and the scaffold enriches trace level contaminants that fungus can degrade. We aim to unveil the fundamental biodegradation mechanisms of the NFF system, which provides future guidance to modify and improve the system. The engineered NFF system will offer a novel strategy that applies toward a broad range of environmental pollutant bioremediation practices.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $282,118 )
2025	2025	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	001	5	3/18/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$282,118
2025	2025	UNIVERSITY OF MISSOURI SYSTEM	121 UNIVERSITY HALL	COLUMBIA	MO	65211	BOONE	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	003	5	9/10/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2025	2024	TEXAS A&M AGRILIFE RESEARCH	2147 TAMU	COLLEGE STATION	TX	77843	BRAZOS	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	002	4	5/13/2025	NON-COMPETING CONTINUATION	$0
2025	2024	TEXAS A&M AGRILIFE RESEARCH	2147 TAMU	COLLEGE STATION	TX	77843	BRAZOS	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	4	3/17/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $282,118

Issue Date FY: 2024 ( Subtotal = $300,431 )
2024	2024	TEXAS A&M AGRILIFE RESEARCH	2147 TAMU	COLLEGE STATION	TX	77843	BRAZOS	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	4	10/27/2023	NON-COMPETING CONTINUATION	$300,431
														Subtotal = $300,431

Issue Date FY: 2023 ( Subtotal = $300,720 )
2023	2023	TEXAS A&M AGRILIFE RESEARCH	2147 TAMU	COLLEGE STATION	TX	77843	BRAZOS	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	3	10/31/2022	NON-COMPETING CONTINUATION	$300,720
														Subtotal = $300,720

Issue Date FY: 2022 ( Subtotal = $300,996 )
2022	2022	TEXAS A&M AGRILIFE RESEARCH	2147 TAMU	COLLEGE STATION	TX	77843	BRAZOS	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	2	11/5/2021	NON-COMPETING CONTINUATION	$300,996
														Subtotal = $300,996

Issue Date FY: 2021 ( Subtotal = $296,855 )
2021	2021	TEXAS A&M AGRILIFE RESEARCH	2147 TAMU	COLLEGE STATION	TX	77843	BRAZOS	USA	NIEHS Superfund Hazardous Substances_Basic Research and Education	000	1	12/21/2020	NEW	$296,855
														Subtotal = $296,855

Grand Total All Awards = $1,481,120

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Efficient Bioremediation of Environmentally Persistent Contaminants with Nanomaterial-Fungus Framework (NFF)

Award Number: R01ES032708

ORGANIZATION: NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 01/01/2021

PERIOD OF PERFORMANCE END DATE: 10/31/2026

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